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Semaglutide for Weight Loss (Obesity/Overweight) User Reviews (Page 3)

Brand names: Ozempic, Wegovy, Rybelsus

Semaglutide has an average rating of 7.3 out of 10 from a total of 609 reviews for the treatment of Weight Loss (Obesity/Overweight). 63% of reviewers reported a positive experience, while 19% reported a negative experience.

Reviews for Semaglutide

  • eric
  • Taken for 1 to 6 months
  • December 20, 2023

Wegovy (semaglutide) "I tried everything, almost getting gastric sleeve surgery. Thanks to my cardiologist, even my heart is fine, he doesn't want to give me clearance for the operation. He recommended Wegovy. I think this is the best decision I ever made. I started on November 2nd, 2023, and until now, December 20th, I have lost an incredible 30 pounds. I now eat only two times a day. I used to eat lots of sweet stuff, but not anymore. No more late eating. I eat very small portions and I feel full all day. I love you, Wegovy, it's real. I am on a 1mg dosage. I was 331 pounds and now I am 301 pounds, with a goal to lose 40 more pounds by July. Good luck everyone, there's a chance because of Wegovy."

10 / 10
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  • Sherry
  • Taken for less than 1 month
  • July 9, 2024

Wegovy (semaglutide) "I’m on the starter dose 0.25 mg. I have had zero side effects. Mild nausea in a car - not sure if related? No real appetite, but I am able to eat. No food aversions, but no cravings. I didn’t want a glass of wine after work. My clothes already feel different after 2 weeks. I’m so thankful to be on this journey as my primary did not support me asking for help losing weight. I do not overeat or have issues with food. I had a fractured knee, then a hip replacement, and then two fractured ankles. I was unable to move normally for 2.5 years and gained about 50 lbs. The weight gain brought on joint pain, trouble breathing, sleep apnea, afib, raised blood pressure, and cholesterol. Hopefully in 6 months, I will be down 40-50 lbs."

10 / 10
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  • Slwis...
  • Taken for 1 to 6 months
  • February 11, 2022

Wegovy (semaglutide) "I'm on my 13th week at 1mg now. I love it. Yes, I was nauseated at first, but the quick weight loss results made me want to continue. At this dosage, I am not really hungry for food, and if I do feel hungry, it doesn't take much food for me to feel satisfied. I have really cut my portions and also use high fiber, high protein foods. Constipation is real; people, laxatives help. I make good food choices now and am down 25 lbs. I want to keep going, but the coupon has run out, and now my out-of-pocket cost with insurance is around $900. I am so disappointed to have to stop and worried about gaining back or not losing anymore. Novo really needs to make this affordable. The price is ridiculous, and millions of people are dying from comorbidities to obesity every day. I have high-end insurance, and still cannot afford the copays."

9 / 10
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Frequently asked questions

  • Dunc
  • Taken for 1 to 2 years
  • January 9, 2024

Wegovy (semaglutide) "I started off taking Ozempic then switched over to Wegovy. I only experienced mild side effects such as nausea and headaches in the beginning of starting these meds. This medication worked for me and helped me lose over 60 lbs. In the past, I have tried numerous diets, supplements, bariatric surgery, and programs to help me lose weight and all failed. This is the only medication that truly worked for me and I'm so glad that I was able to tolerate it. Life-changing experience for me."

10 / 10
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  • Lala...
  • Taken for 1 to 6 months
  • June 10, 2023

Wegovy (semaglutide) "I started 3 weeks ago, and every Monday I inject myself with a 0.25 mg dose. I started this medication because at age 47, even though I tried so hard to exercise and diet, my weight was a roller coaster ride and I would bounce back to my heaviest weight. My weight when I started was 170 lbs, which was 3 weeks ago. After a week, I am down to 159 lbs, then the second week 157 lbs. I weighed myself yesterday and I am down to 155 lbs, that's 15 lbs less. The first week I had a little heartburn, and the second week I was a little dizzy because you can go a day without being hungry at all. By the end of the second week, I had no side effects at all. I am surprised that again I can go a day without being hungry at all, but of course, I force myself to eat something; even with food, I will eat but will be so full easily. I take protein shakes daily as my meal replacement. I'm taking fiber (gummies) so I can go to the bathroom with no problem, and it helps a lot. Overall, I am pretty happy with the result."

8 / 10
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Are you taking this medicine?

  • poisonB
  • Taken for less than 1 month
  • April 3, 2023

Wegovy (semaglutide) "Been on Wegovy for half a week. For my first injection, I used the upper right side of my stomach. Within an hour, I had a bit of shooting pain in my left mid-back section. I was a bit concerned but didn't say anything to anyone about it as I figured it was just my body getting used to a new chemical. I'm now on day 3, and no pain anywhere, no nausea, and feeling pretty great. I am a little concerned about not understanding exactly what my caloric intake 'should' be but will discuss it with a dietitian. My dosage was the starter 0.25 mg, and my starting weight is 228 lbs. Let the journey begin! Already got past one of the biggest hurdles, namely doing the injections myself. The needle is super small, and didn't leave any marks or blood! Super fast, and recommend it to the 'needle-adverse' folks. I am very glad that it is only once a week though."

8 / 10
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  • LADw
  • Taken for 1 to 6 months
  • July 4, 2022

Wegovy (semaglutide) "I took Wegovy for a few months and did, in fact, lose some weight. The side effects are terrible, as so many others have noted here. One thing that they don’t tell you is that the drug slows down the stomach's ability to empty. This is why people feel full and experience reflux, nausea, etc. In my case, the drug not only slowed down my stomach's ability to empty, it permanently paralyzed my stomach muscles, a condition called gastroparesis. The only remedy was to have a neurotransmitter implanted in my stomach, which forces the muscles to move. Do NOT take or first this medication. You could end up like me with a lifetime medical issue. No weight loss is worth that."

1 / 10
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More FAQ

  • Me22
  • Taken for 1 to 6 months
  • March 31, 2022

Wegovy (semaglutide) "Just finished the last shot of 2.4 mg pack. I’ve lost 27 pounds and literally do not think about food. No cravings, and I eat normally (albeit smaller amounts). Some side effects at the beginning but nothing terrible and they all eventually stopped. If you can afford it - this is a life changer."

10 / 10
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  • Lorra...
  • Taken for less than 1 month
  • October 3, 2023

Wegovy (semaglutide) "I was prescribed Wegovy for weight loss purposes. I'm 5'11 and 225 pounds with a BMI of 31%, so I can be considered obese. I've been on it for one week and have lost 7 pounds. I'm starting with the lowest dosage (.25). First of all, the injection was completely painless (for me). I also inject Humira bi-weekly, so maybe I'm just used to it, but I was shocked to feel absolutely nothing. I questioned if I was doing it right because it was so painless. Do not let some testimonials scare you! I did a lot of research while waiting for the drug to come back into stock. 90% of what I read were complaints about vomiting, diarrhea, and some people getting so sick they had to stop taking it. Some of these reviews were written after only a week or two of using the drug. So far, my personal experience has been completely different from what I've read. That could change as I increase the dosage. As of right now, the only side effect I'm experiencing is a complete lack of appetite."

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  • Stalled
  • Taken for 1 to 2 years
  • February 15, 2024

Wegovy (semaglutide) "It has been a year since I have been on Wegovy. I went up to 2.4 by August 1, 2023, and had lost 50 pounds in those six months. The last 6 months, I have not lost any weight. I have not gained but definitely stalled for 6 months. I just went down to 1.7 last week to see if the high dose 2.4 is the reason for the stall. Appetite suppression also stopped at 8 months. No clue what to do, but I will stay on 1.7 for a month to see if it changes the stall. Good luck everyone! I have a whole new life after losing 50 pounds! Life is good!"

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  • Bonnie
  • Taken for less than 1 month
  • June 10, 2023

Wegovy (semaglutide) "Honestly, I have never been so sick in my life. 1st and only dose of wegovy made me so incredibly sick. I have been in the hospital twice for excessive dry heaving. There is no stopping the symptoms. I had short term relief with IV sedatives and anti nausea medications. Still a week later now at home throwing green bile. I will never recommend to anyone."

1 / 10
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  • jmm
  • September 27, 2022

Wegovy (semaglutide) "For me, it is a miracle drug! I have had no side effects and have been on it since December 2021. I was trying other medications that helped a little, but I was stuck teetering between 190-195 and could not pass that. As soon as I started Wegovy, the weight started to come off. I am now right around 160, and I am close to my goal. I am also 60 years old, which makes weight loss even more difficult. I highly recommend this treatment!"

10 / 10
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  • Fingers...
  • Taken for 1 to 6 months
  • July 5, 2022

Wegovy (semaglutide) "57-year-old on this for 3 1/2 weeks. I'd like to tell you how much I lost (was 4 pounds at 3 weeks), but I am so constipated for 4 days I cannot be sure what my real weight is (it could be 6 pounds now). Get a telemedicine provider to send you a vial of semaglutide (not the pre-loaded syringes) and use an insulin syringe to administer 1/2 the dose on one day with an ODT Zofran, then take the second half of the dose 24 hours later with another ODT Zofran. I administer in my outer thigh, like you would give insulin. The provider will tell you exactly how many 'units' to administer per week, just cut it in half, say Saturday and Sunday. Take a stool softener on Sunday, which I forgot to do this week! I have had zero gastrointestinal issues, no nausea, no vomiting. The Zofran may be causing some of the constipation, and I don't consider this a real issue, just a minor side effect with an easy fix. I am a Nurse Practitioner, so I have been watching everything for real side effects. I'll update."

10 / 10
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  • MRS
  • Taken for 1 to 6 months
  • January 10, 2022

Wegovy (semaglutide) "I have been taking Wegovy since August 2021. I am down 45 pounds. I did low carb with this which has really helped me to lose the weight I have wanted to lose. The side effects are very real, extreme constipation and nausea for two days after injection. The doctor prescribed Zofran for the nausea and I have taken a stool softener for the constipation. All things said, it really helped curb my appetite. But you have to diet with it."

9 / 10
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  • ShellB
  • Taken for 6 months to 1 year
  • May 1, 2022

Wegovy (semaglutide) "I began Wegovy in late August '21. I had bariatric surgery in 2000. Menopause, major life changes, and COVID resulted in a 60 lb weight gain over 5 years. It's May 1, and I've lost a total of 81 lbs. My BMI has gone from 38 to 25, and I never got to the 2.4 injection. I had slight nausea and 2 incidents of gastrointestinal uncertainty ('sharts') the first 2 weeks, but nothing after that. I walked 1.5 - 2.0 miles 6 or 7 days weekly, ate a high-protein, low-carb diet, switched to 50/50 Stevia/Sugar as a sweetener, and ceased eating after 8 pm nightly. I feel great, and because of my weight loss, I can delay my other hip replacement. Wegovy gave me a second chance at better health, and I'll continue to use it for maintenance."

10 / 10
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  • Kelly...
  • Taken for 1 to 6 months
  • May 4, 2023

Wegovy (semaglutide) "I have been on Wegovy for almost 7 weeks, and have lost over 22 lbs. From the moment I took the first injection the food noise was gone. At times it feels progress is slow, but in truth the progress has been steady. I have not started dieting or exercising, I am focusing on eating healthier and listening to my body for signs that I am full. I have heard of bad side effects, though I personally have not experienced any. Prior to this medication I have lost, gained and relost 50-100 lbs over and over again."

10 / 10
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  • Mike
  • Taken for 1 to 6 months
  • March 21, 2022

Wegovy (semaglutide) "Drug has been life-changing. When I began, I was 6'3'' and 357 lbs. Today is exactly 4 months in, and I'm down 60 lbs exactly. Blood pressure meds cut in half, discontinued Lasix and potassium pills. Currently taking 2.4 mg/weekly. My side effects have been relatively non-existent. Early on, some gastro upset and heartburn, but all went away with time."

10 / 10
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  • Highly...
  • Taken for 1 to 6 months
  • April 18, 2023

Wegovy (semaglutide) "I was worried about side effects with this medication, but I have not had any. So far, I have lost 16 lbs in two and a half months, with diet and exercise. I started with the 0.25 mg dose, and I am now on the 1 mg dose. I would recommend it to others who want to try it."

10 / 10
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  • ShyFox
  • Taken for 1 to 6 months
  • November 1, 2021

Wegovy (semaglutide) "Been on Wegovy for 7 weeks. Lost 14 pounds. 2nd week into 0.50 mg. It’s a little rough on my stomach. Taking prescription for nausea which happens the day of the injection. Feel tired and occasionally get severe abdominal pains. I can’t eat much and have to really watch the types of food. No greasy foods or spicy or heavy. The intestinal pains were very severe after eating wrong foods. I’m happy with the weight loss but the side effects are rough."

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  • Erica
  • Taken for 1 to 6 months
  • March 29, 2023

Wegovy (semaglutide) "I've been on Wegovy for a little over a month now. My first injection of the 0.5mg dose was on Friday (3/24/23). The weight loss has been fairly slow but steady. The main thing that I've noticed is that it makes me feel full after I eat. I know it sounds strange, but for some reason, I've never felt hungry or full—I ate when people told me and didn't stop eating until my plate was clean since I was a kid. Now, after I eat a bit, I feel full and stop eating. I've learned to be choosier with what I eat, opting for healthy things, protein and fiber, and less fat and carbs. No crazy fad diets or anything, just being more mindful. My injections are on Fridays, and I've noticed that Sundays are the worst days, but after 2 weeks on a dose, the side effects are pretty minimal. Just started the 0.5mg dose and so this past Sunday was bad, but my doctor gave me a PRN script for Zofran to help with nausea. I hope this review helps someone."

8 / 10
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  • WagOn
  • Taken for less than 1 month
  • April 5, 2023

Wegovy (semaglutide) "I took my first shot of 0.25 five days ago. I was extremely nervous about taking it due to all of the negative side effects that I read others have had. I decided to inject in my upper thigh late on a Friday afternoon so that if I did feel sick, I had the weekend to take it easy and deal with it. The injection was painless and very easy to administer myself. I honestly noticed no side effects after taking it, other than not thinking about food as much and wanting to eat a little less. I did push the boundaries on the third evening after taking it, and I did have bad nausea; I actually vomited and felt generally ill for about 16 hours (not bad enough to not work though). I pushed the boundaries by overeating air-fried chicken wings (no sauce) that were a bit more greasy/oily than normal. Those really set me off, and I realized that I: 1. can no longer eat any type of greasy food and 2. cannot eat too much. As long as I stick to my normal healthy, low-carb diet, I feel just fine (so far)."

9 / 10
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  • Never...
  • Taken for 1 to 6 months
  • June 10, 2023

Wegovy (semaglutide) "Let me first say that digestively, I have never been more miserable in my life than I was on this "medication." Wegovy gave me abdominal cramps so bad I had to go to the ER. I was very dehydrated and in so much pain. Luckily my CT was normal, but my WBC was elevated. Maybe this is some other side effect that will start being reported more often now that half the population seems to be taking it. I started at 0.25 mg and did that weekly for 4 weeks. During that time, I was ok but constantly felt somewhat bloated and would burp way more than what would be considered normal. I am glad some people had success with this but for me, my life was better before this medication. I'll take being "overweight" and feeling great to this any day. I just hope there is no permanent damage. Thanks for the misery, Wegovy. Never again. Big pharma can take their bogus, fabricated BMI and stick it. They want people to be miserable and addicted to whatever drug they cook up for their investors."

1 / 10
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  • TBH
  • Taken for less than 1 month
  • February 25, 2023

Wegovy (semaglutide) "Started 2/23/23. 0.25. 64 years old, H 5/6, W 217. Only side effect is dizziness when standing up and subsides with a minute or two. That seems to be hypoglycemia. As of today 2/26/23 it has definitely curbed my appetite. I will check back in a month to let you know my progress."

8 / 10
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  • Big...
  • Taken for 1 to 6 months
  • April 24, 2023

Wegovy (semaglutide) "I have been on Wegovy for over a month now, it has been a life changer for me. Very few side effects. I have way more energy, I can fit into clothes that were so tight I couldn't wear them, and I have fewer aches and pains. My mindset is so different. I am 5 11', started at 263 lbs. (Obese) I have lost almost 15 lbs. This stuff pretty much keeps those hunger cravings away. I have changed my eating habits as well, I only eat fruits, veggies, and salads, I do plan on going back to some of my other favs' but for now, I'm sticking to no pasta, pizza, bread, or desserts. I only eat between the hours of 6 am to 3 pm. I have been walking around a 1/2 mile per day on my lunch breaks. I do not eat much, seems like I get full very quickly. Another benefit, I have bitten my nails my entire life, since starting Wegovy, I have not touched them, it's quite unbelievable."

10 / 10
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  • Tough...
  • Taken for less than 1 month
  • March 14, 2023

Wegovy (semaglutide) "I am on my 3rd 0.25 dose of Wegovy. I feel terrible most of the time. I have lost 5 lbs and am definitely not hungry due to nausea. My prescriber will not prescribe Zofran with Wegovy, because she feels nausea that severe should be considered a negative side-effect and the medication stopped. That's reasonable. I read the reviews before I began the med and take Omeprazole daily, as well as MirraLax. I am 57, menopausal and used to feel really good most of the time. Sadly, this med is not worth the side effects for me. I really, really wanted to tough it out but as a nurse, I feel it's creating problems that I did not have before taking this medication. The nausea is constant, the belching/burping is so frequent that its embarrassing, stools are like a rock, and the worst feeling of chest tightness. I had so hoped I would be one of those without adverse side effects but I am not."

3 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.