Skip to main content

Quetiapine for Borderline Personality Disorder User Reviews (Page 5)

Brand names: Seroquel, Seroquel XR

Quetiapine has an average rating of 7.6 out of 10 from a total of 129 reviews for the off-label treatment of Borderline Personality Disorder. 67% of reviewers reported a positive experience, while 9% reported a negative experience.

Reviews for Quetiapine

  • Seroq...
  • Taken for 1 to 6 months
  • September 7, 2023

"I have been on countless meds for most of my life, and nothing has ever really worked. About a year after I got diagnosed with BPD, I suffered the loss of a parent, and everything was spiraling. My psychiatrist put me on quetiapine (Seroquel), and it has changed my life more than I thought any med could over the past few months. I truly feel like I’m in control of my emotions for the first time in years and years. I am so much less paranoid, and it helps with my social anxiety a lot. I am taking quetiapine (Seroquel) and trazodone at night, and that is the least amount of meds I have ever taken, and I’ve never done better. I highly recommend quetiapine (Seroquel) if you have BPD and are offered a prescription. I have tried so many meds, ketamine treatment, everything. Nothing has helped me like quetiapine (Seroquel). I have had to up my dose, and I hope my body doesn’t build up a tolerance too much because it really helps me stay calm and collected."

9 / 10
Was this helpful?YesNo
1 Report
  • Catgirl
  • Taken for less than 1 month
  • May 29, 2022

"I have Borderline Personality Disorder BPD and before I was diagnosed with that, I was just taking meds for anxiety and depression and it was making me feel worse. When I finally found out I have BPD, I was prescribed quetiapine. I have only been on it for about 2 weeks now, but literally after just a couple days I noticed a difference. The biggest difference I noticed is that it pulled me out of my disassociation and calmed down my emotions. I feel like for the first time I’m actually able to process things and not just react. It also helps me sleep through the night ! Before I would go to bed super late, constantly having cold sweats, and wake up like 10 times during the night. I know it may be too early to see the full benefits, but already it has done wonders for me in so many ways I never would have realize"

10 / 10
Was this helpful?YesNo
2 Report
  • Ali
  • Taken for 2 to 5 years
  • May 30, 2022

"One of the few things I have found really keeps me calm and reduces the manic episodes, both highs and lows. Another plus is that it pretty much knocks you out at night so there’s no worries sleeping either. Can be difficult to wake up properly some days though. I take 150mg every evening."

9 / 10
Was this helpful?YesNo
2 Report

Frequently asked questions

  • Lux
  • November 20, 2020

"I have mixed feelings about this drug. I was originally on 75mg of Quetiapine for about 3 years for insomnia and it helped massively getting to sleep but it made me feel as though I had a hangover the next day. I have currently been an inpatient for the last 4 months and it was increased up to 400mg, this is when the major side effects came into play. First side effect that was very apparent was weight gain: I went from about 65kg to 80kg in the space of 2 months. As well as it being obvious I put on weight it also made my hands and face swell. Another side effect was not being able to stay awake, if you are to take this drug I suggest taking it on a night and not throughout the day as it makes you very sedative. The major side effect to me was my pulse, about an hour after taking the medication my heart rate rocketed to about 160bpm, luckily I was in hospital at the time so a DR saw me straight away and I was taken off the drug."

3 / 10
Was this helpful?YesNo
3 Report
  • kathr...
  • Taken for less than 1 month
  • July 24, 2023

"I started taking 25-50mg of quetiapine at night a few weeks ago, and it has helped me a lot. I sleep better, I am more calm, and (for me, most importantly) I am less impulsive. My psychiatrist and I are slowly working on upping the dose as I can feel the effect slightly fading throughout the day, especially by the end of the day, but it makes me really tired, so we haven't changed it yet. The only side effects I have experienced are a dry mouth and a little morning grogginess, much better than all other medication I have used for my BPD. Also, I am currently going through a break-up, and I think the medication is helping me super well. I am sad and crying, but my emotions are not over the top, and most importantly, I haven't thought about suicide in a while. I feel like it has stabilized me a lot. Other people will certainly need a higher dose as I am small and relatively thin."

9 / 10
Was this helpful?YesNo
1 Report

Are you taking this medicine?

  • Pezzo
  • Taken for 1 to 6 months
  • January 25, 2018

"I am on 50mg morning and 200mg night as well as zopiclone and diazepam 5mg when required. I have not started zopiclone dose as nobody sticks to it lol. I think the quetiapine is helping as I feel less anxiety and paranoia generally than I did before. My focus is better at work. I think I would benefit from a higher dose but the doctors don't think there will be any benefit only harsher side effects."

8 / 10
Was this helpful?YesNo
4 Report
  • Derby...
  • September 17, 2021

"I am prescribed 50mg quetiapine In the morning. 50mg In the afternoon and 200mg at night alongside diazepam when needed. I'll be be completely honest with you it did make me gain weight over the 3 years I've been on this medication. I was always around 13 stone and I'm 5"9 I went up to 16 stone. I'm now down to 14 stone as it's had the adverse effect on me and now I don't eat. Where as before I ate a lot."

10 / 10
Was this helpful?YesNo
2 Report
  • Dally...
  • Taken for 1 to 2 years
  • February 21, 2019

"I have been taking 100mg quetiapine 3 times daily with 150mg lamictal and hydroxine. The quetiapine doesn't make me tired but I also do not wake up all through the night. I do see myself rather anxious throughout the day."

6 / 10
Was this helpful?YesNo
3 Report
  • Nessie
  • Taken for 2 to 5 years
  • September 18, 2021

"I’ve been on and off seroquel ever since I was diagnosed with borderline personality disorder in 2017. I was diagnosed at 17 and I’m 21 now. I started on 25mg and got increased steadily to 100mg from 2017-2019. I quit taking my meds several times over the years bc nothing was working and I attempted suicide 5 times in 2 years. In 2020 I got back on seroquel, only seroquel, on 50mg. It has helped reduce my mood swings, impulsivity, paranoia, and psychosis. I am able to sleep so well when I take it. When I miss dosages bc I run out, the withdrawals feels like I am dying, I cannot sleep or eat, the psychosis is absolutely horrendous, I have horrible headaches, and restless leg. I was just increased to 100mg from 50mg bc I had a psychotic episode and the only issue so far is my heart is racing for about an hour after I take it which makes my paranoia worse. It has only been 2 days on 100mg so hopefully it evens out. But I feel good on this medication it is the only thing that works."

8 / 10
Was this helpful?YesNo
2 Report
  • thewi...
  • December 15, 2017

"Hi! It's been almost 3 weeks since I've started taking Seroquel XR 50mg, once a day. I'm taking it mostly for impulsivity and mood swings (but the official Borderline diagnosis isn't out yet). It knocked me out good the first night, but didn't achieve to make me sleep alright since then. It doesn't knock me out that much, and my mood swings are back since this week. I have doubts about its interaction with birth control, since it seems to affect the hormonal system quite a lot. Do I need to precise that I weight about 115 lbs for 5.4 ft? I'm tiny. I thought the Seroquel would knock me harder than that, and maybe I had put a lot of hope in it. I will see how it goes during the Holidays, but probably going to ask if I can start taking 100mg."

7 / 10
Was this helpful?YesNo
3 Report
  • Langers
  • Taken for 1 to 6 months
  • December 28, 2022

"Since my diagnosis of Borderline Personality Disorder (BPD) which took multiple different Psychiatrist’s over 10 years to diagnose me with BPD. I was told that quetiapine would help dampen down the symptoms. I was also told that there is no cure for BPD. To date I have been taking the medication for just over 2 months and I can safely say that I feel no relief from the medication. Each day is a struggle and sometimes extreme anxiety, stress and mood changes. I still have suicidal thoughts on occasion. Since days can be extremely unbearable to the point where I stay in my room and try to sleep because it's the only relief I get. Drs are very quick to throw tablets at you, and in their mind, you'll be ok. This is far from the truth. I have been mentally ill for over 10 years with multiple suicide attempts and hospital admissions. Nothing changes. Nothing has helped. I don't know why it isn't working, but all I know is that it is not. You can talk about your feelings, but that is a short fix"

2 / 10
Was this helpful?YesNo
1 Report
  • Hailey...
  • Taken for 2 to 5 years
  • October 17, 2017

"I am a 24 yrs old female. I was on this medicine for 4 years 400mg The weight gain side effect was bad... I from 52kg I went to 83kg I was drowsy Everyday my pupils were dilated I looked like a crazy person... The worst side effect was that I couldn't walk suddenly... and it happened twice during my 4 years... I couldn't walk for 2 weeks for both And it caused a lot of inconvenience And It's also very pricey... BUT it did help me with my mood. My emotional anger and tears outburst were better And when your less emotional you are less likely to cut yourself I really miss taking this medicine My new doctor stopped it and he won't allow me to take it and my mum is also against it because of its side effects."

2 / 10
Was this helpful?YesNo
3 Report
  • Anonymous
  • Taken for 1 to 6 months
  • June 16, 2022

"Been taking quetiapine 25mg every night for 3-4 months. No weight gain, no tremors, no eye movement problems. Really tired and sedated the first few weeks. Maybe a little water retention over my abs for a while but the scale never went up. Just be sure to stay active to keep your metabolism going and watch your calorie intake. As for actually helping me, I'm only taking an antipsychotic because I'm being forced to, so if you're in a similar situation, ask to try seroquel(quetiapine) if you're afraid of side effects because they're low for me and I'm prone to unusual negative side effects. I have gotten better at controlling my anger and self harm after I started taking it, but that's probably just because I've been putting more effort in so I can leave this facility. It's more helpful if I take it as-needed, which I have it prescribed for as well as at night time"

7 / 10
Was this helpful?YesNo
1 Report
  • tamara
  • Taken for 1 to 2 years
  • March 8, 2024

"I finally got 25mg per day, and it helps me to sleep. I could go up to 5 days and nights not sleeping in distress. In turn, I feel less angry; anxiety has reduced. I would highly recommend it for BPD. No unwanted side effects either. About once a week, a worry can override it, so maybe I need a higher dose occasionally. I think drugs are avoided for BPD, and yet I find it really helpful."

10 / 10
Was this helpful?YesNo
0 Report
  • heather
  • Taken for 1 to 6 months
  • May 30, 2024

"I can't explain how much this medication is helping me. I was suffering so bad with my mental health where I'd end up in a mental health unit to be constantly assessed. I've been on so many medications including sleeping tablets and pills like diazepam and lorazepam. I was firstly put on 25mg standard of quetiapine and I felt drowsy at first and then got used to them very quickly, but then the dose was raised and I couldn't cope with the bang of the sedation, so I was put on the prolonged-release. I'm on an antidepressant too, but my god, I can actually walk to the local shop on my own. I'm short-tempered now though, and I get so angry very easily, which is the con, and I've put on some weight, but yeah, 2 pills a night and I'm starting to feel myself again a bit."

9 / 10
Was this helpful?YesNo
0 Report
  • Rio
  • Taken for 6 months to 1 year
  • June 9, 2024

"I've been taking quetiapine 25mg and it works perfectly. I have BDP and I take lamotrigine and topiramate. Before quetiapine, I couldn't sleep well. I used to listen to sounds that don't exist. The medicine helped a lot. In the 7 months I have been taking it, I didn't gain weight (could also be influenced by my eating disorders). But whenever I stop taking quetiapine, I can't sleep. Overall, it worked perfectly for me."

10 / 10
Was this helpful?YesNo
0 Report
  • Wooly...
  • March 1, 2015

"Managed to stabilise my mood swings on only 100mg daily, helped greatly with sleep however, did leave me feeling drowsy during the day"

9 / 10
Was this helpful?YesNo
30 Report
  • Saroq...
  • February 27, 2009

Seroquel (quetiapine) "Made me a zombie. I could sleep for 24 hours after one pill. I have things to do I can't sleep that long."

1 / 10
Was this helpful?YesNo
41 Report
  • Phiep...
  • Taken for 2 to 5 years
  • April 26, 2020

"This quetiapine medication has helped me a lot, it helps me sleep but also stops me from experiencing awful nightmares. Which I suffered with massively before taking it, I also have (c-ptsd)."

9 / 10
Was this helpful?YesNo
10 Report
  • livin...
  • November 23, 2009

Seroquel (quetiapine) "I have noticed a decrease in BPD symptoms just days after taking this medication (25mg) - the reason why I gave it an 8 is because I can only take it at bedtime since it makes me very sleepy!"

8 / 10
Was this helpful?YesNo
23 Report
  • Mkla
  • Taken for 1 to 2 years
  • March 5, 2018

"It takes the edge off my emotions & makes everything bareable. Any higher than 25mg I personally wouldn't go for. In my opinion any higher would dull your personality"

8 / 10
Was this helpful?YesNo
12 Report
  • Mvina...
  • Taken for 6 months to 1 year
  • March 22, 2017

"Work well to reduce my fluctuations in mood especially with getting frustrated and angry..."

8 / 10
Was this helpful?YesNo
13 Report
  • jaxxy
  • Taken for 1 to 2 years
  • September 12, 2020

"I gain a bunch of weight on quetiapine, another side effect was really bad restless legs after my dose. When I do finally fall asleep I'm out cold!"

5 / 10
Was this helpful?YesNo
8 Report
  • wolly
  • Taken for 2 to 5 years
  • March 27, 2024

"I love quetiapine. I am on 50mg at night for anxiety due to BPD. I don't know what I would do without it."

Was this helpful?YesNo
1 Report
  • Bulma
  • Taken for 1 to 6 months
  • June 10, 2017

"I've been treatment resistant to everything but this. It saved my life. Only problem is the slight weight gain and dry skin."

7 / 10
Was this helpful?YesNo
8 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Borderline Personality Disorder

Care guides

Symptoms and treatments

Medicine.com guides (external)