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Quetiapine for Borderline Personality Disorder User Reviews (Page 3)

Brand names: Seroquel, Seroquel XR

Quetiapine has an average rating of 7.6 out of 10 from a total of 129 reviews for the off-label treatment of Borderline Personality Disorder. 67% of reviewers reported a positive experience, while 9% reported a negative experience.

Reviews for Quetiapine

  • BPD...
  • Taken for 2 to 5 years
  • January 1, 2015

"I was on and off Seroquel for 3 years. It helped with my depression and most of my anxiety, certainly put a stop to my insomnia. I hated the way I would feel when I woke in the morning though. I hated not being able to just get up and go, it usually took until mid afternoon to feel 100% clear. I found though that after a few years its effects on me at 100mg were wearing thin. It no longer helped with my paranoia at all and I would be up half the night. I also gained nearly 20kg, stopped taking it and have dropped over 10kg so far. Also having my daughter seems to have shifted something mentally and found that I no longer need to continue taking it to control everything."

8 / 10
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  • apple
  • Taken for 1 to 6 months
  • March 22, 2019

"I've been taking seroquel 100mg at night and wellbutrin 200mg in the morning for about a month for Borderline personality disorder. I was previously taking seroquel 50mg and wellbutrin 200mg but was still having problems. My mood is overall better. I have more energy and am more talkative and not as fearful. I don't read into things as much. When I do get upset, the reaction is much less severe. I still have some racing thoughts when triggered but the severity is less. I seem to forget things almost instantaneously at times though which makes conversation and focusing a bit difficult. My husband says things have going well with us for a while now. That's really something since that hasn't happened in our marriage ever before. What's helped also is learning CBT skills."

8 / 10
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  • Anonymous
  • April 16, 2011

Seroquel (quetiapine) "Seroquel changed my life. After roughly 20 years of treatment with medications for borderline personality disorder I had a new doctor put me on Seroquel. At first I resented the sedation, but after time I adjusted to it and the dosage was moderated and timed differently. Ultimately, however, it was the first medicicne to thoroughly handle my anxiety, and stop my obsessive thoughts in their tracks. The only downside has been the carbohydrate cravings and weight gain, but even those have become manageable with other supplements and medications. The gains far out weigh losses."

9 / 10
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Frequently asked questions

  • Ragin...
  • Taken for 1 to 6 months
  • February 6, 2021

"I found the low doses of 25mg, 50mg, 75mg slow to adjust to but overwhelmingly positive after a while I found that 75mg was no longer as effective so moved to 100mg. I have a very fairly fast metabolism so I often have an intense reaction to medicine and drugs. I tried 125mg for 4 days and I started having shakes, 3 hour adrenaline rush, constant moving, suicidal thoughts, intense uncontrollable rage/anger. Reduced my dose back to 100mg and all side effects have disappeared. In general I feel much better within myself. My mood ranges have become far less turbulent and I am slightly less irritable in general. Will continue to to monitor and maybe reduce again to 75mg."

7 / 10
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  • Shan
  • Taken for 1 to 6 months
  • February 13, 2020

"I've been on 25mg for about 3 months and it's helped LOADS with my sleep, I've had terrible insomnia for most of my life and nothing else has helped, but my god this was like a sedative when I first started! It doesn't make me as drowsy now but definitely have a more regular sleep pattern now. It hasn't really stabilised my mood but I think it has helped with dissociation, and I haven't gained a lot of weight but I am finding it hard to lose weight. One of the better drugs I've tried!"

8 / 10
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Are you taking this medicine?

  • yx_y
  • Taken for 1 to 6 months
  • November 10, 2019

"I wish I had quetiapine 18 years ago since, I had suffered from serious insomnia, OCD, anxiety and deep depression for so many years. Half year ago I was diagnosed as BDP. I have started quetiapine and it helps a lot. Almost no more OCD symptoms. My dose is 100mg in the evening for 2 weeks and it has changed my feeling a lot. Only thing is with 100mg , I sleep for 11 hours per day. It is really too much......"

8 / 10
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  • Hazza
  • July 19, 2012

Seroquel (quetiapine) "I have been on these tablets for 3 days now, for border line personality. I've been so tired after I take the 100mg at night but my anger is still a problem, and I'm feeling a tiny bit less like I'm lonely and no one understands me and my emotions. But honestly not much of a change. I just still don't know if my life's going to get any better."

6 / 10
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  • maisy...
  • April 13, 2014

"Been on quetiapine a month for borderline personality disorder and possible bipolar and a mild psychosis, take 25mg three times daily. I love it my moods and anxiety are much more stable and so are the voices. I do take it along with Depakote 2000mg, lamotrigine 100mg, zopiclone 7.5mg, diazepam 5mg and lorazepam 1mg as needed and haloperidol 5mg as needed but definitely the quetiapine that's sorted my head."

9 / 10
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  • yorki...
  • December 20, 2011

"Well I'm back again and have now been on quetiapine for three years. During that time I've had no major problems. In fact I've been stable enough for my doctors to agree to me having a gastric bypass to deal with my weight issue and have now lost 7 stone and have more confidence than ever before. Quetiapine helps me get to sleep but doesn't knock me out for as long as before. I average 8 hours per night, but still tend to have an afternoon nap. The gnawing anxiety only returns for short periods when under a lot of stress. The downside to quetiapine? I wonder if it makes me unable to empathize. My dad died recently and I've coped far too well. life is a nice warm cosy blur. But the alternative was torture for years."

8 / 10
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  • Gaz
  • Taken for 2 to 5 years
  • May 27, 2020

"I’ve been taking Quetiapine now for about 4 years my dosage started on 100mg and over the years it was raised to 500mg. I found the tablet to help my mental condition as my personality has changed following my brain haemorrhage. However my overwhelming concern was the weight that I had gained 4 stone! So in December 2019 I gradually started to reduce my dosage and now I only take 200mg at bedtime as it helps me to sleep as I wouldn’t be able to sleep without taking the Quetiapine."

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  • pooks
  • January 6, 2012

"I have been on Quetiapine XL 50mg (with a 25mg as required for more difficult days) for about a year now following a history of poor sleep, self-harm, overdose, binge eating, depression and hospitalization. The difference it has made to my life has been amazing, far more beneficial than all the anti-depressants I have been on over the years. At first I also struggled with the sedatory effect but with persistence it reduces and can be managed. The main reason I have decided to post is because yorkiegal mentioned being unable to empathize. I too have noticed that I do not seem to be as 'affected' by sad events/news as I feel I should be, sometimes feeling a bit disassociated."

8 / 10
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  • Anonymous
  • November 18, 2010

Seroquel (quetiapine) "This medication is adequate compared to others in its class, despite it still causing significant side effects such as weight gain (which is very undesirable). At first, this medicine seemed very strong and made me 'zombie-like' (e.g. slow, unemotional, sleepy) but after a couple of days these were significantly improved. I was on a dose of up to 75mg, and as far as the effects of each individual dose; 25mg help with sleep and 'anger management', 50mg increased my hunger (a lot) and 75mg helped a little more with anxiety and emotional stability."

7 / 10
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  • Matt
  • Taken for 1 to 2 years
  • April 19, 2020

"I’ve been on 300mg of quetiapine for over a year. Was diagnosed with bipolar disorder but I’ve now been recently re diagnosed with BPD (borderline personality disorder) the quetiapine is very draining. Constantly sleepy. And made me put on a lot of weight. Even if I’m controlling my eating. But does stable my mood out to an extent.I’ve also been put on Lamotrigine recently due to trying to attempt to take my own life. Wasn’t too sure about taking it as it has a black box warning due to it’s serious side effects. Only side effects I am experiencing is dizziness/ headaches. And loss of appetite. Seems to be working okay"

8 / 10
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  • Mr L ...
  • April 24, 2017

"In my experience Quitapine is most effective for regulating sleep. 25mg a day before bed is all you need, anymore seems far too much and can make you very sedated and a very constant sluggish and lazy feeling throughout the whole day. I've had real problems with not sleeping and this stuff knocks me out for the best nights sleep. I'm not sure how or if it truly helps with intense mood changes, depression or rebalancing serotonin and dopamine levels in the brain, what it's designed to do, because I still have issues with stability and mood changes etc but it definitely helps with regulating sleep and that in itself plays a huge beneficial part on my mental health. Quitapine is the best so far, I've tried 8 different medications for Bpd."

8 / 10
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  • I C
  • Taken for 1 to 6 months
  • April 4, 2021

"Well I started on 25mg and it was okay but I would still feel extreme rages, soo I went up to 50mg. It did help me a lot, I realised that things that I would usually overthink weren’t actually that big of a deal. I was continually having relationship problems soo I started going up until 100mg. And now I’ve realised that it’s not actually helping that much. I’m not as emotional and wild as I was, and I can see a positive, but I feel like I miss the old me! I miss feeling everything and expressing myself with real emotions. Now I feel more motivated, but I don’t feel like me any more. I’m more quiet and I still get the rage, I still get upset and overwhelmed, just not as much. It does work, but I’m gaining soo much weight and I want to be the old me. Maybe with some therapy when Covid is over and try something else, but I’m going to slowly drop downs to 25mg and then come off of it because I don’t want to be on this for years."

7 / 10
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  • nickn...
  • Taken for 6 months to 1 year
  • August 10, 2020

"quetiapine works excellent for sleep @ a dose of 25mg . I gradually increased my dose to 50mg after a couple months and now take slow release at night and it works great. No super negative side effects besides wanting more water/ thirsty."

10 / 10
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  • BPD_F...
  • Taken for 1 to 6 months
  • November 26, 2014

"Diagnosis: PTSD, Borderline Personality Disorder, Avoidant Personality Disorder I've been taking Seroquel for 2 months now. Hospitalized for an episode. My thoughts were super distorted, probably from lack of sleep in combination with my disorders. Obsessive thoughts that wouldn't stop. Intrusive thoughts over past traumas (PTSD). Couldn't get to sleep at night without sickening dreams. I finally got my life back with this stuff. I got a job, but I was working night shift, so I only lasted 2 days. Night shift and these meds are hard to manage. But my health is more important. The only thing that is a downside is that I can't drink on it. The nights I do drink I don't take the Seroquel. If I do take it I try and wait til I sober up."

8 / 10
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  • KingS
  • Taken for 1 to 6 months
  • August 17, 2023

"I used to be so insecure and my mind would be so fragile and unable to perform properly, as if I couldn't act with any confidence or self-esteem. But with 150mg of Seroquel, I felt extremely confident and free. It was like a switch being flipped. It's a miracle, really. And it helps me sleep so deeply, and I love the 'drunk' feeling at the end of the night when you're on the verge of falling asleep. It makes me feel so calm and my confidence levels just skyrocket, allowing me to do things that 'normal' people do. I really can't believe it, and I'm so grateful. I wonder what 200mg would feel like. It also helps with my schizophrenia (I hear voices and have hallucinatory mental pressure). The only side effect is that I have really unusual visions in my mind as I'm about to fall asleep, and I also hear different voices at that time. But when I wake up, I feel like a new person and much more symptom-free."

9 / 10
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  • madun
  • Taken for 2 to 5 years
  • March 4, 2017

"It helps with the constant horrid intrusive thoughts, I still feel like I'm behind glass, although I'm easily destabilized, the sedation helps calm me, I've put on 6 stone in 4 years, restless legs and sometimes arms, however for me, I would take this medication because it's giving me enough stability to stay "living""

7 / 10
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  • kas
  • December 27, 2016

"Taking it for Borderline Personality Disorder/Emotionally unstable personality disorder(EUPD). An effective mood stabilizer and helps with paranoia and occasional psychosis. The drowsy side effect has helped with my insomnia as my sleep was awful. I'm on 300mg at night. The other side effects are a pain though. I've put on 4-5 stone (56/70 lbs I believe) at least, whilst I've been on these possibly from the munchies it gives me but I'm sure it's altered my metabolism.. After taking the dose, my nose blocks up completely. I have to use a nose spray every night. My heart pounds and I get restless legs and arms. It feels like something tickling them on the inside. I always feel drowsy in the mornings but that is to be expected."

6 / 10
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  • Pezzo
  • Taken for 6 months to 1 year
  • February 2, 2019

"I have reviewed this drug before and this time are just posting an update. I'm on 100mg morning, 200mg night. My moods are regulated with minimal inappropriate reactions and outbursts, my sleep is regulated, my anxiety and paranoia are minimal, all in all quetiapine is doing a wonderful job for me. Only thing is I've put on 3 stone in the recent months it gives me the mega munchies for sweet goodies."

8 / 10
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  • Gwend...
  • Taken for 1 to 2 years
  • June 1, 2013

"I have been on Seroquel XR for almost 2 years now, and am at a dose of 400mg. If I drop down to 300mg I become unstable in my mood again. This medication has helped me become stable, I rarely become "high", due to this I have not self-harmed in a year and 6 months. The weight gain has made me uncomfortable, especially considering that the medication can make me very hungry. However, my weight has now stabilized and I ave a BMI of 28, so its not too bad. I still become very angry sometimes, but attribute this to my own behaviour and coping mechanisms. Overall, this has given me my life back. My family and friends have noticed the change in me and I feel that I can appear "normal"."

8 / 10
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  • Prylux
  • November 9, 2016

"I recently was admitted to a Psych Ward for a suicide ideation/attempt. I've previously been diagnosed with ADHD and Borderline Personality Disorder. I was taking 70mg Vyvanse 1x a day, 300mg Wellbutrin XR 1x a day in the morning and 20mg of Paxil 1x before bed . The psychiatrist in the hospital discontinued the Paxil and prescribed 100mg Luvox 2x a day and 50mg Seroquel before bed. I've been taking the medication for 9 days. I wake up tired and feel tired the whole day. I also feel jittery but that could be because I drink caffeinated beverages to help stay awake. My Hope is these effects wear off."

7 / 10
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  • Hello...
  • May 13, 2013

"I have been on quetiapine for just over a year now for Borderline Personality Disorder and Post Traumatic Stress Disorder. For the first 3 months all I did was sleep as I was 700mg, lost 2 stone then I got used to it and put weight back on, after lowering the dose 2 months later I was fine. I am now on 100mg, still have the odd problem and only been in hospital once more, I still see things and compared to how I was last year I am a completely different person. I'm a lot calmer, the voices in my head have calmed down, the feelings of intense rage have reduced and I can now talk to people. Only downsides, weight gain and my sex drive has fallen completely."

8 / 10
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  • M3gzz
  • Taken for 2 to 5 years
  • October 16, 2018

"I have been though many drugs, and none helped as I was thought to be bipolar. Now at 30 I have been re diagnosed with BPD, which fits better! I have been on quetiapine since 2014 and it's been a life saver, but makes total sense because I'm not bipolar. Anyways I feel like I can function without emotions ruling my every move. The only downside is the weight gain and occasional morning drowsiness (more so then normal, like falling back to deep sleep while sitting up)."

8 / 10
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10 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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