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Quetiapine for Borderline Personality Disorder User Reviews

Brand names: Seroquel, Seroquel XR

Quetiapine has an average rating of 7.6 out of 10 from a total of 129 reviews for the off-label treatment of Borderline Personality Disorder. 67% of reviewers reported a positive experience, while 9% reported a negative experience.

Quetiapine rating summary

7.6/10 average rating

129 ratings from 136 user reviews.

Compare all 28 medications used in the treatment of Borderline Personality Disorder.

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Reviews for Quetiapine

  • Sarah
  • Taken for 1 to 6 months
  • February 1, 2021

"I’ve been taking 25mg of Quetiapine at night for a month. I was wary of the weight gain; however, I have not gained any weight. I do watch what I eat and walk for around 30 mins to 1 hr every day. I think it’s best to take it at night as it does make you very sleepy. I do feel some slight hunger, so it’s best to take it at night to avoid urges to eat or overeat. In terms of mental health, it has completely changed my life. I went from crying for hours a day and torturing myself with overthinking, to finally being able to feel grounded and live my life like a ‘normal’ person. I haven’t changed, and I’m not ‘doped’ out all the time as some people may imagine when someone takes a drug like this. I actually feel positive about my life, and it has allowed me to have some hope for overcoming BPD or managing my symptoms. I would definitely recommend this drug. However, I am aware that people have different reactions, but for me, it’s been very beneficial, and I hope my review can help someone else too."

10 / 10
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162 Report
  • Anonymous
  • April 23, 2010

Seroquel (quetiapine) "Seroquel has completely changed my life for the better. I was recently diagnosed with Borderline Personality Disorder. It didn't really matter what label the psychiatrist gave me as I already knew and understood my problem to be unbearable pain - regardless of any formal title. I experienced racing and obsessive thoughts, acute paranoia, immeasurable anxiety, and the terrible lows, gripped by depression. Unstable, rapid emotions and was tired, having had to live with this unrecognized illness. I reached a point where not only did I want to die, but I seriously considered taking the life of my child also and had reached a definite crisis. I've been taking it for only three months and I'm unrecognizable to the person I once was. I value life and feel amazing about myself and endless possibilities for the future."

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  • Inger...
  • December 1, 2016

"My daughter was prescribed this dreadful drug by a supposedly consultant psychiatrist. Her weight doubled in just over a year. This drug gives you suicidal thoughts and my daughter committed suicide on 16th November 2016. Reading her suicide note was heartbreaking. The Seroquel never helped her in any way so she tried to come off them, and the withdrawal effects were horrendous. I believe that her mental condition got worse when she was on this drug. I would never recommend this medication to anyone. I live in the UK."

1 / 10
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152 Report

Frequently asked questions

  • CMac
  • Taken for 2 to 5 years
  • July 1, 2020

"I have been on Seroquel for 5 years now. I began at 100mg and just recently moved to 200mg. Prior to Seroquel, my BPD symptoms were out of control. I was misdiagnosed many times over my lifetime and have been given countless drugs for depression and anxiety, which either did not work or made things worse. Since being on Seroquel, my life has completely turned around. I feel totally in control of my thoughts, emotions, and actions. I feel rational and sane, have impulse control, have been able to hold down a job and maintained a nice lifestyle and marriage for the entire time, which I was never able to do before. I take it at bedtime, it's the ONLY thing that helps me sleep at night, I wake in the morning feeling rested and alert. I do struggle with being overweight by about 40lbs, but the benefits far outweigh the weight side effect for me."

10 / 10
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  • cb1617
  • January 27, 2021

"I have been diagnosed with Borderline personality disorder (BPD). I’m 20. I was depressed and suicidal when my psychiatrist put me on seroquel. Itook 4-5 months for it to fully kick in. 300mg was too much for me my mornings were horrible and I fainted a couple of times. my heart was beating so fast when I woke up and I would get so dizzy it was so hard to start my days properly. I wouldn’t go back to 300mg - also made me feel like a potato, because I never felt sad anymore. I am now taking 150mg which is working soooo well for me. I am finally happy and I have reached a point of emotional stability and consciousness which I have never had previously. It makes me feel like I have seen the real life on the other side. I was so blinded due to bpd and now seroquel - only (no dialect treatment) made me feel so confident and the person I’ve always been looking for. I’ve been on it for 9 months and I can’t imagine my life without it. I might be addicted to it but IDC - I would never go back to my bpd it scares into the thought of living in that nightmare."

10 / 10
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Are you taking this medicine?

  • Anonymous
  • April 21, 2012

Seroquel (quetiapine) "I have been suffering with borderline personality disorder almost my entire life. Within a few days of taking Seroquel, I noticed an incredible difference in my mood balance and my paranoia. The biggest difference I noticed was I no longer felt the need to be in crisis. Social settings were easily handled, and my work life improved overnight. I used to use alcohol to expand on my crisis moments, and friends and family believed me a hopeless alcoholic. Now I have no urge to drink. I wake up focused, ready, and able to face the day. Most of my days are almost completely positive. I would recommend."

9 / 10
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115 Report
  • Venus
  • Taken for 1 to 2 years
  • July 31, 2020

"I'm a 23 y/o woman diagnosed with borderline personality disorder at age 18. I take 25mg quetiapine once daily and this medication has gotten my psychotic symptoms under control as well as getting my co-morbid generalized anxiety disorder under control. I also take .25mg xanax as needed for spikes of anxiety and it works like a charm! I used to not be able to sleep through the night without waking up hallucinating and it was a nightmare. Now I actually sleep and during the day it's made my psychotic symptoms completely go away. The only con I've noticed is the morning grogginess but that's eased as I've gotten used to the medication. I absolutely recommend this for anyone with BPD specifically struggling with psychotic symptoms."

10 / 10
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  • Dylan
  • February 14, 2020

"Firstly, when I began this medication, I thought it was a godsend. I was prescribed it while in a behavioral health center and went from waking multiple times a night to sleeping a solid 8 hours and waking mostly refreshed, once the grogginess stepped aside. My mood evened out and my will to live was finally there. I was happy. I have been on this medication since November and it is now February and things have gone from wonderful, to complete rock bottom. My anxiety is through the roof and I've even developed false memory syndrome which has caused rampant paranoia in my waking life. I no longer sleep through the night because I'm jarred by horrifying nightmares built around my OCD intrusive thoughts and deep fears. I'm exhausted, depressed, and have absolutely no appetite anymore. It also has since caused me a lot of physical symptoms like severe nausea, body twitches, and diarrhea nearly every day. The honeymoon phase is over and I am miserable."

1 / 10
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46 Report
  • K1987J
  • February 22, 2016

"Started on 50mg Quetiapine today. Knocked me out for 4 hours, but once I came round again, there was almost instant relief from obsessive thoughts, paranoid ideation, anxiety, and the world seemed much slower. Much easier to handle. Kinda feel like there must be some kind of catch to this deal? Scared of weight gain, but I'll monitor it and let you all know how that goes. So far, I'm loving it."

10 / 10
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72 Report
  • tyfer...
  • August 28, 2014

"Been on quetiapine for a couple of years now, and this medicine changed my life. I am a better person now, and this medicine helped a lot with that. No crises, no anxiety, no craving for alcohol or other medicines. Sometimes I think I could be more emotional, but it's a price I had to pay for having peace in my head. Totally recommend. I take only 50mg per day, and it's enough to keep me stable."

10 / 10
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79 Report
  • Looper
  • Taken for 2 to 5 years
  • March 3, 2020

"Quetiapine gave me back my life. I haven't attempted suicide in 4 years. Great mood stabilizer. Helps with insomnia and puts you in a deep sleep. It has made me mentally stronger. Downside of it is the side effects, I've developed involuntarily movements and twitching in my shoulder and weight gain."

10 / 10
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40 Report
  • shams
  • October 10, 2019

"I noticed a difference at 75mg, and am almost feeling 'normal' at 150mg. It helps with dissociation, agitation, self-harm, as well as levels out my moods. I've only been at 150mg for ten days, but I was cautiously optimistic at 75mg and am almost hopeful with at 150mg . I haven't felt particularly hopeful about anything in years :) I did go through a period of cravings, but they've since levelled out. I also try to exercise 4x a week; I don't own a car so I walk etc. I don't feel as if my personality is deadened ..I feel more me, not less."

9 / 10
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  • Scooo...
  • Taken for 2 to 5 years
  • September 27, 2014

"I was on this medicine for almost three years and went off of it cold turkey because I thought I was better. Worst mistake of my life in 2013! A month or so ago I was put back on the medicine, just not quite as a high of a dose (800mg). I am now on 300mg and it has once again changed my life. I am happy again, feel like me, don't crave alcohol or other pills, and the mood swings have pretty much dissipated. This medicine is amazing and a life saver."

10 / 10
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61 Report
  • marci...
  • April 3, 2010

Seroquel (quetiapine) "My life has almost completely turned around... in the best ways possible. Other medicines never did anything good or just nothing at all, and they just kept upping the doses on me. Then they started me on this crazy expensive medicine, and I tell you, it's just amazing! It is totally worth it... my social life is back... I have my friends back... and close family members. Well, it feels like I'm loved again and there's nothing really to think and think and think over and over and over again anymore, and sleeping is good again. I can sleep and not worry or think. Just totally worth it."

9 / 10
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79 Report
  • LeeM
  • January 16, 2017

"I have recently been diagnosed with Borderline Personality Disorder. I have had symptoms of this for years not knowing what was wrong with me. I would go a few years with no issues cause I was drinking very heavily ( 1- 2 cases of beer a night) I have tried SSRI's as they would not work with the depression and anxiety. I recently was switched from zyprexa to quetiapine 100 mg (will be increased to 200mg in 2 days.) It has been 3 days and I have already noticed a complete difference. My thoughts seem a lot more stable, I'm not as paranoid, I found my anxiety has lessoned (I was having 4 -6 panic attacks at work a day) and I just feel more stable now. I am very grateful as to I was so desperate for help."

9 / 10
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48 Report
  • Gccc
  • May 22, 2020

"I've been on quetiapine for 3 years I have borderline personality disorder, and I don't think they work for me I take 400mg at night, other than making me tired all the time with no energy and weight gain, I wouldn't recommend and they come with many common side effects, and prior to taking them I actually think I was better off, they are very addictive to, I've forgotten take them on a odd occasion and the withdrawal procces feels like I'm dying"

2 / 10
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29 Report
  • spazpen
  • August 19, 2014

"I have only recently been diagnosed with Borderline Personality Disorder but I have suffered it's effects my whole life. More recently I had an episode where it was necessary to be admitted to hospital extreme agitation/hyperactivity and suicidal and self harm thoughts. I was started on 12.5mg three times a day in hospital but on discharge was advised that I could take up to 25mg three times a day as I felt necessary. So far I've only needed 12.5mg two times a day, occasionally with an extra dose at night or a stronger dose in the morning for bad days. I've found the groggy feelings wore off after a couple weeks and I'm so balanced now. Seroquel has changed my life."

10 / 10
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  • Panda...
  • Taken for 1 to 6 months
  • November 2, 2013

"Prior to taking this drug I was in a self-destructive, dissociated state of paranoia and anger. At times I would have these intense mood swings that I was unable to control, like sadness (burst into tears with no provocation) or anger (no provocation). Upon taking this drug this ceased within 1-2 days, and it was as if I had never been like that. I was restored, so to speak. This drug saved my life, I feel it fair to say. Side effects: I sleep very heavily, I need about 30 alarms going off five minutes apart before I wake up, and I get extremely drowsy if I have even a little alcohol, I also have very low moods for a few days after consuming alcohol."

9 / 10
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55 Report
  • drew
  • May 5, 2014

"I found Seroquel(quetiapine) to be the best medicine for me it really helped my thoughts slow down and allowed me to regain control of my thoughts/emotions, it also helped with my insomnia which was an added benefit. I also take an antidepressant and it seems to work well with it as I used to get bad headaches from the antidepressant alone but since adding Seroquel to it I no longer get these headaches. I guess if I had to say one negative thing about it, it does seem to increase my appetite /possible weight gain but I feel the benefits outweigh the negative as the increased appetite/mild weight gain can be controlled by eating healthy and exercise. Overall a great medication for me."

9 / 10
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48 Report
  • icanh...
  • Taken for less than 1 month
  • May 6, 2016

"I used to be always in a hurry always so anxious and had horrible mood swings. I didnt realize it was getting worse until suicide came into play and my bf broke it off and called the cops. i was freed but the following days I did not eat or sleep and was constantly agonized by thoughts and feelings and cried oceans. I turned myself in at the hospital (3 days ago) and have been put on sequorel (retard). I must say the thoughts are still there but its not as agonizing. My body is relaxed and I feel like I can breathe again and enjoy the small things in life. Im still hoping my bf will come back...that obsession remains. I sleep well...I've started dreaming again. Nice dreams mostly. I like this drug but am a bit worried about the side effects"

10 / 10
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  • Joe...
  • August 19, 2016

"Try being on these meds a while and see how you feel. They will ruin your life and there impossible to get off. I've lost myself and when I stop I'm manic to the point of hurting myself badly just to feel something. I can't put into words what they've done to me but a quick fix is never the way."

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  • Anonymous
  • February 6, 2010

Seroquel (quetiapine) "The first week was a little difficult for me. I was a total zombie the first few days. Once I got to my target dose of 300mg, things quickly evened out. I'm full of energy, I'm not as anxious or paranoid as I used to be, and I'm finally able to go to sleep and STAY asleep. Before I took Seroquel, I felt terrible. Like my life was just a dream, and that nothing and nobody, mattered at all to me. After taking Seroquel for just a week or two, I immediately felt real again. No more mood swings, no more crazy ideas of self harm, no more social problems! Seroquel has turned my life around. It might not work this well for a lot of people, but I sure hope it does."

9 / 10
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  • Hedon...
  • Taken for 1 to 6 months
  • December 21, 2016

"Quitiapine turned my anxiety into anger and severe suicidal ideas. Anxiety turned into anger and made me act badly toward my family Although I stopped quetiapine 4 months ago, and these symptoms have mostly disappeared, I still have to deal with child protection services and similar legal issues. If your doctor prescribes this, be VERY careful and notice any sign of negative change."

1 / 10
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  • bpdja...
  • Taken for less than 1 month
  • October 29, 2014

"I'm currently on a dosage of 50mg morning, 50mg afternoon, 100mg night. I requested my psych add this to my current medication, which is Welbutrin XL(300mg). The results have been strikingly positive. I personally have not experienced any significant side effects from either besides some minor weight gain. This combination is the first to make me feel hopeful, bring me out of a resistant depression and help with anxiety. Mood swings seem to be minimized compared to before this. They still happen but in a less extreme nature. I'm able to feel comfortable on my own, instead of going to a bar for company. I have yet to have the classic meltdown...I've experienced mental clarity that's been absent for years."

10 / 10
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  • yorki...
  • September 29, 2008

Seroquel (quetiapine) "I'm three weeks into taking 200mg of Seroquel along with my usual Effexor. I was prescribed it off label to help with the mood swings I get from being borderline. For the first time in years I am not full of anxiety. I sleep longer, am able to exercise in public without feeling self conscious, am eating more healthy foods, although still too much of them. The drowsiness was awful initially but has mostly disappeared now."

9 / 10
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57 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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