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Phentermine and Insomnia: What Users Say

Brand names: Adipex-P, Lomaira, Atti-Plex P

Insomnia: mentioned by 294 users (9.8%)

Based on user experiences from 3,014 Phentermine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

dry mouth 26.7%
insomnia 9.8%
headaches 6.9%
anxiety 6.4%
constipation 4.5%
increased heart rate 3.6%
loss of appetite 3.0%
dizziness 2.7%
tremors 2.7%
nausea 2.6%

Reviews for Phentermine

Commonly mentioned side effects
  • its...
  • Taken for less than 1 month
  • August 20, 2020

Phentermine for Weight Loss (Obesity/Overweight) "I started Lomaira (phentermine) on 8/13/20. I'm 5'10 and my weight was at an all-time high of 218 when I started. My doctor had me start with a half dose (4mg) and half dose of Topiramate (generic Topamax -12.5mg) for two weeks. Then I will move to a full dose of each for the rest of the prescription. I have been drinking a gallon of water a day, eating a low-calorie diet, and doing light exercise daily. My appetite is controlled, my energy is up, and my system is cleansed. I have lost 10 lbs in one week. I do need to take it earlier in the morning because it's hard to fall asleep. But I'm looking forward to feeling like myself again. Best of luck to all of you!"

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  • She...
  • May 20, 2019

Phentermine for Weight Loss (Obesity/Overweight) "It does work. You have to work with Adipex though. You have to stay hydrated. You have to eat at least 1000 calories if not 1200 daily. You have to exercise a little. Even if it is just walking. You need to also take it very early and take it around the same time each day, like 6 am or 7 am. I would not go past 8 am if you are sensitive to medications. Otherwise, you will be up all night long, ready to run around. You also need to change the foods you eat. We are fat because of what we eat. This is not a magic pill that will melt your fat away. You need to correct yourself for it to really help you on your weight loss journey. This is all common sense. It raises your heart rate up (it's almost like speed). That is what gives you the energy that we are all lacking. For me, Adipex is a fantastic appetite suppressant. Good luck."

8 / 10
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  • Ano...
  • Taken for 1 to 6 months
  • April 2, 2025

Phentermine for Weight Loss (Obesity/Overweight) "For years, I struggled to drop the extra weight I put on after having my second child. I tried everything from online programs to workout DVDs, but I always hit a plateau. When my doctor recommended Lomaira, I was honestly pretty skeptical. But two and a half months later, I’m down nearly 10 pounds, and it actually feels like it’s sticking this time. I started at 168 pounds, hoping to get down to 150. One 8 mg pill a day has seriously helped cut my late-night munchies and sugar cravings. Surprisingly, I haven’t felt jittery or had trouble sleeping, which was my biggest concern with a stimulant. Instead, I’ve got more energy, which is a huge help when you’re juggling kids and a busy schedule. I still have a bit more to lose, but I’m really happy with how far I’ve come. If you’ve been stuck in the same frustrating cycle, it might be worth talking to your healthcare provider about Lomaira. It’s done wonders for me, and I finally feel like I’m on the right track."

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Frequently asked questions

  • Kri...
  • Taken for 6 months to 1 year
  • July 19, 2014

Phentermine for Weight Loss (Obesity/Overweight) "I started off on the highest mg, which is 37.5, and it has worked very well for me. In my first month, I had lost 26 lbs, and in 6 months, I lost a total of 90 lbs. I DID NOT EAT HEALTHY NOR DID I EXERCISE. I took a break from it a couple of months back because it's not safe to take it for an extended period of time due to the fact that it takes a toll on your liver. I just got back on it again yesterday. It will cause you to have DRY MOUTH, CONSTIPATION, URGES TO DRINK LOTS OF WATER, ENERGY, ABILITY TO STAY FOCUSED, INSOMNIA, FAST HEART RATE, MOOD SWINGS, NAUSEA, AND EASES BODY PAIN. I have a heart murmur and panic attacks, so after taking this medication, I notice it gets harder for me to breathe as the day goes by."

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  • Bug...
  • June 3, 2020

For Weight Loss (Obesity/Overweight) "I just started taking 37.5 mg of Phentermine yesterday for weight loss. After struggling with diets, exercise and medication weight gain, my doctor and I decided this was the best way to help me shed the 10-20 pounds I’ve been wanting to lose for at least 6 months. First and foremost, take this pill as early as you can because it did affect my sleep. On the first day, I only experienced light jitteriness, a little chest pain, and a headache. My appetite was lessened. Today (the second day) I am already down a pound, I’m not very hungry at all, and I only have mild jitters and a headache. Nothing that isn’t tolerable though. I plan on taking this for a total of 3 months only, so I’m hoping I’ll drop the excess weight I’ve gained and develop healthier practices while I’m on it. I will say that the increased energy is nice for someone who wasn’t sleeping well and then wasn’t motivated to move around."

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  • Nor...
  • June 3, 2020

For Weight Loss (Obesity/Overweight) "5'11 and I weigh 170, yes I'm tall but this is the heaviest I've been and I'm not happy with it. Side effects: no sleep, lower back aches, dry mouth, made me angry which I'm never angry. Also here and there a little depressed. But I would have to snap out of it very quickly. But overall it's a good pill to take if you have self-control and you won't get addicted to it. It gives you lots of energy which I like to work out in the gym or go for a jog at a park. You will lose weight quickly but you have to maintain it. I have a sweet tooth so I would eat chocolate after I lost all my weight then I would see I gained weight like 2 lbs and I would work out the next day. You have to be consistent and dedicated."

10 / 10
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  • Blo...
  • January 28, 2020

Phentermine for Weight Loss (Obesity/Overweight) "I have been on Adipex for two weeks. My doctor suggested it to help me lose some weight. I was 200 pounds at the start. I am now 194 lbs after 2 weeks. I take a half pill a day. I work at a desk all day and would have issues with snacking all afternoon. Now I don't. I force myself to eat some fruit every afternoon or a protein shake. I can't eat a full meal because I feel fuller faster. I have more energy. I have had dry mouth, but drinking water is a big help with that, and I drink a lot more water. I do have some heart racing at times, but the more water I drink, the better that is, which is good because it did throw me into a few panic attacks. No headaches. I did get insomnia the first two nights, but I switched to taking the pill at 10 am instead of noon and that stopped. I started exercising so hope to see more weight drop off. My goal weight is 145, but I am only taking this until my bottle is gone."

8 / 10
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  • Lad...
  • July 13, 2021

For Weight Loss (Obesity/Overweight) "Taking this medication for 4 months now, I was 203 pounds in March and down to 169 pounds now (July), feeling good. I'm 33 years old, I've always struggled with my weight and binge eating disorder, but it got worse during the pandemic. I was binge eating every day, and I couldn't control it - I was 203 pounds, the heaviest I've ever gotten. I was uncomfortable in my own skin, so I decided to look for help because I couldn't do it on my own, even though I tried. The doctor prescribed phentermine. It took away most of my appetite and cravings - I felt hungry, but I would eat just the necessary. I still have binge eating episodes when I have PMS, but not as bad as before. Not many side effects for me, just a VERY dry mouth, it made me drink more water, which is good. I experienced insomnia sometimes, and a little headache and constipation in the first week. I recommend it to people who want to get healthier but can't do it alone, just don't forget that you have to be strong to keep the results. It's not a miracle pill."

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  • big...
  • Taken for less than 1 month
  • November 12, 2013

Phentermine for Weight Loss (Obesity/Overweight) "I just started Adipex 3 days ago. I'm having some insomnia and terrible dry mouth. But I also have mad energy and a little appetite. Adipex is amazing! Compared to having no energy, terrible depression, and feeling like there was no hope, I feel great! Hopefully, this continues - don't give up, there is help out there!"

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  • Gin...
  • Taken for 1 to 6 months
  • January 30, 2015

For Weight Loss (Obesity/Overweight) "I started phentermine right before Thanksgiving. I am 5'2'' and starting weight was 184 lbs. It made me not hungry at all. I constantly drank water and ate very lightly. No insomnia first month. I lost 17 pounds. Second month I had to take 3 days off because of the insomnia. If I feel I can't sleep, I will skip a day or two. Still only drinking water and eating lightly. No exercise at all, and today I weigh 156 lbs. Total loss of 28 lbs in two months. This month I plan to add exercise to drop more weight. Love Phentermine!"

10 / 10
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  • Que...
  • Taken for less than 1 month
  • December 21, 2019

Phentermine for Weight Loss (Obesity/Overweight) "Started Adipex late October, now it is in the middle of December. I have lost 20 pounds. The pill literally cut my appetite, and I drank water. No sweets, breads. I really didn’t exercise, but housework, working, and being a full-time Mom and Wife. I guess you can say that’s where it came from. The only side effects I had were dry mouth and insomnia, nothing too bad. Oh, and yes, I could have lost more weight, but I skipped some days taking the pill."

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  • Cyn...
  • Taken for 1 to 6 months
  • February 22, 2020

For Weight Loss (Obesity/Overweight) "I was 215 lbs, now 179.5 lbs. My goal weight is 140 lbs. I lost 36 lbs in the 3 months that I took phentermine. I did not feel hungry and had energy. I did have dry mouth and had trouble getting enough sleep. I feel that it is well worth the side effects. I drank plenty of water and would take OTC meds to help with constipation. I also would recommend taking the medication as early as possible so that by the late evening, you can sleep. I have been off phentermine for 3 weeks now and am having trouble losing. I have not gained any weight. My doctor put me on Wellbutrin to continue to help me lose weight. I have less energy, and it really doesn't help much with hunger. I am doing intermittent fasting, and hopefully, I can lose enough until I can get back on the phentermine in 5 months."

10 / 10
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  • AWL...
  • Taken for 1 to 6 months
  • October 6, 2014

For Weight Loss (Obesity/Overweight) "So far this is absolutely the best aid in losing weight for me. I had lost 75 lbs in 2011 with Weight Watchers but gained about 38 lbs back between 2012 and 2014. I went to the doctor and he put me on phentermine & chromium picolinate. I have been on this since 8/23/14. In 6 wks I have lost 25 lbs. It has significantly decreased my appetite to where I don't even think about eating and have to remind myself to do so. The only side effects I have had are dry mouth, which causes me to drink water constantly (so not a bad thing), mild insomnia the first 2 wks & constipation, for which I just take a supplement. BUT you have to eat right. Reduced carbs for sure. Weight Watchers taught me healthy eating so you do have to change your food."

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  • 49e...
  • Taken for less than 1 month
  • February 9, 2020

For Weight Loss (Obesity/Overweight) "I'm a 37-year-old male, 6'3'' and 375 pounds. I'm on my 2nd, almost 3rd day of taking phentermine 37.5 mg dose. I will say I am no longer hungry, but do eat once a day. The worst thing about it is that I can't sleep. I have a very busy work life and was hoping burning energy off would help, but no. I can't wait to go into the doctor in April and see how much weight I've lost. My goal is to lose 75 pounds by the end of the year."

9 / 10
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  • SMC...
  • Taken for 1 to 6 months
  • August 4, 2019

For Weight Loss (Obesity/Overweight) "I began taking phentermine on June 18th, 2019, with a starting weight of 295 lbs at 5’3”. During the first few days, I was very jittery and had trouble sleeping, however, after a week, I was able to adjust, and now the only side effect is dry mouth/thirst. I drink about 100 oz or more a day in water. I cut out all liquids holding calories and cut back on processed food while introducing more whole grains and fresh fruits and veggies. I have PCOS, so losing weight can be very difficult. I also started YAZ to help level my hormones while losing the weight. I began increasing my activity levels slowly by avoiding the elevator at work and utilizing the 5 flights of stairs several times a day (took 4 weeks to work up to this), and now I have begun using my tree climber at home in addition. It’s been 6 weeks, and I am down to 266 lbs, for a total of 29 lbs loss. Each week, I increase my activity and lessen my processed food. My goal is 150 lbs."

9 / 10
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  • WOR...
  • April 30, 2013

Phentermine for Weight Loss (Obesity/Overweight) "Started my first dose Thursday 4/25 weighing 222 lbs. Today 4/30 I am at 209.5. That's a 12.5 lb loss in 6 days! Can't wait to see where I'm at on day 30! Only side effect I had was trouble sleeping. Started taking Unisom and problem solved. I never got dry mouth because I drink close to a gallon of water a day. So far so good so I'm going to keep on keeping on!"

10 / 10
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  • los...
  • Taken for 1 to 6 months
  • October 14, 2014

For Weight Loss (Obesity/Overweight) "When I started Phentermine, I weighed 181 lbs. Today was my 1-month weigh-in, and I am at 167 lbs. I have lost 14 lbs in 1 month. I am 5'6" and 22 years old. I am coupling Phentermine with a healthy low-carb diet, around 1,200 calories a day with only 20 minutes of cardio a day. Loving the results and have had no serious side effects other than trouble sleeping for the first 2 days."

9 / 10
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  • Anonymous
  • September 15, 2008

Phentermine for Weight Loss (Obesity/Overweight) "I started using Adipex in March 08, weighing in at 332 lbs. As of September 08, I am now 284 lbs. I lost 48 lbs in 6 months. At first, I had a little trouble going to sleep, but that went away after a couple of weeks. I think that the pill is totally worth it. Now I have really picked up my exercise routine, and I am very cautious about what I eat. I have very little starch at all. My exercise consists of 3-4 miles on the treadmill at 6-7 mph and then 30-45 minutes in a sauna every day. I would suggest taking the pill for 2-3 weeks, then laying off for a week. This is what has worked for me."

9 / 10
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  • Anonymous
  • March 3, 2008

For Weight Loss (Obesity/Overweight) "I had the same sleep problems and found that if you only take half the pill around 8:30 am and the other half around 11, then I was good around 11 pm to crash. I also found that if I took it earlier (a whole pill) I was able to fall asleep earlier."

10 / 10
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  • KGR...
  • Taken for 1 to 6 months
  • September 24, 2024

For Weight Loss (Obesity/Overweight) "I started taking phentermine on June 16, 2024, and weighed 168.5 pounds. I take 30 mg. I am now down to 144 pounds and have been for a while. I combine the phentermine with intermittent fasting. I do still have problems sleeping once in a while, but I feel so much better about myself! I'm hoping that I can keep the weight off once I stop taking it since I have changed my eating habits."

9 / 10
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  • Anonymous
  • January 25, 2010

Phentermine for Weight Loss (Obesity/Overweight) "I started taking Adipex on November 17, 2009. It is now January 25, 2010. I have to admit when I first started taking Adipex, I felt like I was on straight speed. I couldn't sleep, eat, or concentrate. I still have bad mood swings and get upset very easily. I have no problem sleeping, that wore off the 3rd week. I tend to get hungry later in the afternoon. I was taking a half of a pill the first month. I take one pill a day now and do great, except for my mood swings. My starting weight was 165 lbs. I now weigh 138 lbs. That's a weight loss of 27 lbs. I still have 8 lbs to go. I exercise 5 days a week on the treadmill for 30 minutes each time. If you are really wanting to lose weight and can overlook the side effects, this is the pill! Good Luck!"

10 / 10
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  • Ind...
  • April 5, 2015

For Weight Loss (Obesity/Overweight) "Started phentermine by my new Dr on 4/1/15, 286 lbs. Will weigh again in a week but so far I have no food cravings lost most of my appetite. Only eat 3 small meals. I feel a little nauseous when I think about eating. I have tons of energy, but when it is time for bed, I can't sleep. If I knew this pill was so effective, I would have started when I was 230 lbs. I don't know why my old Dr never recommended it. I'm really excited, and I promise to keep you posted."

9 / 10
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  • Tkb...
  • Taken for less than 1 month
  • August 14, 2014

For Weight Loss (Obesity/Overweight) "I am 40 years old. I started taking Phentermine 37.5mg 6 weeks ago, and have been doing a 2000 calorie or less diet (because it is hard to eat that much, just not hungry). Just went to the doctor today, I have lost 23 lbs. I did experience a little insomnia the first couple of days but I take the pill at 5:30 am before work and that seems to help. I sweat a lot for most part of the morning and have a lot of energy but dry mouth is definitely a side effect, but it helps with getting you to drink the amount of water you need to be drinking if you are not a water drinker like me. I do have a significant amount of weight to lose so hopefully the weight loss continues at this rate."

10 / 10
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  • sar...
  • Taken for less than 1 month
  • June 5, 2015

Phentermine for Weight Loss (Obesity/Overweight) "I went to a weight loss clinic on Tuesday, June 2nd. I have been battling my weight for years (ever since I had 4 kiddos). I'm 5'5, and my starting weight was 184.4 lbs. I started the prescription the same day that I had it filled, and as of today, Friday, June 5th, I am down to 177 lbs! This is absolutely unreal! 7 lbs in 3 days! I have had slight insomnia, constipation, and crazy dry mouth, all of which are easily solved. A little melatonin for sleep, cascara sagrada for constipation, and tons of water for dry mouth. I can't wait to see where I am at the end of June!"

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  • Jen...
  • Taken for less than 1 month
  • August 29, 2019

Phentermine for Weight Loss (Obesity/Overweight) "I have been taking this medicine for 20 days, and I’ve had minimal side effects. It’s made me more irritable, and the first 2 days of taking it, it made me feel a little weird. I had trouble sleeping at night for the first week and a half, but I think that’s been resolved. This gave me the kick start that I needed. I don’t know how much weight I’ve lost since starting it and will know when I go to my 1-month appointment. I’ve definitely been losing weight. It’s pointless to take this medicine if you're not actively taking steps to eat right and exercise-something that this medicine helped me kick start. I’ve been exercising every day and have been eating great. This took away all of my cravings, and I haven’t drunk any pop since taking it-that was my biggest weakness. I will post an update as soon as I know. I started at 222 lbs, and I’m 5’7"."

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