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Phentermine and Dry Mouth: What Users Say

Brand names: Adipex-P, Lomaira, Atti-Plex P

Dry mouth: mentioned by 805 users (26.7%)

Based on user experiences from 3,014 Phentermine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

dry mouth 26.7%
insomnia 9.8%
headaches 6.9%
anxiety 6.4%
constipation 4.5%
increased heart rate 3.6%
loss of appetite 3.0%
dizziness 2.7%
tremors 2.7%
nausea 2.6%

Reviews for Phentermine

Commonly mentioned side effects
  • She...
  • February 11, 2020

Phentermine for Weight Loss (Obesity/Overweight) "Started Adipex 11 days ago, weighed myself today and have lost 11 pounds. Started at 181 and am now 170. Going through menopause and have spent the last two years in the gym unable to lose a pound. Once menopause hit, I gained so much that my BMI for the first time put me in an overweight category. I asked my Dr. if there was something I could take that helped the work that I already do actually work. Goal weight is only 155, I'm 5 feet 10 inches tall. The first week she had me take half a pill a day, beginning of second week a full pill. The first day I had a bad headache. I have dry mouth from taking it, but not so bad it's unbearable. I drink a ton of water. It took away my desire to drink coffee and it never gave me the bad coffee withdrawal headaches. I'm eating anywhere from 600-1200 calories. Change your eating habits while on Adipex. Take those few months to get your body adjusted to healthy food choices so that it doesn't crave the bad stuff once you're done taking the pills."

10 / 10
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  • Tik...
  • March 5, 2019

Phentermine for Weight Loss (Obesity/Overweight) "This pill is a magic pill! Only if you take it the right way. I've experimented with it over the past year, the two times I've been prescribed it. It's supposed to be taken 3 months on, then 2 months off. I would take advantage of the 2 months off to appreciate the weight you've lost, and practice discipline and healthy living. What you won't read is, you will gain it back! This pill will give you crazy ENERGY! Use it! The most effective way, I would recommend taking your dose is on an empty stomach. Preferably as soon as you get up. So, if you get up around 6, take your dose. Around 8:30 or 9 eat breakfast. WATER, WATER, WATER! Is your best friend while on this pill, which will have your skin glowing! If you don't drink water or low sugar fluids with this pill, you will have dry mouth, mood swings, and irritability. I will guarantee it. Yes, this is my personal experience."

10 / 10
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  • Xos...
  • Taken for less than 1 month
  • June 8, 2020

For Weight Loss (Obesity/Overweight) "I'm 31 years old, 5'6, 238 lbs. I started Phentermine on 05/27/2020 and so far I lost 12 lbs, down to 226 lbs on 06/08/2020. This is in 13 days. I've seen stories that people lose more than that in two weeks. All I did was take the pills at 7 am and workout for 45 minutes to an hour. I don't feel hungry at all, but you gotta eat. Phentermine makes you feel like a wonder woman and it's not a 'magic pill', you have to exercise and eat healthy. The only side effect I have is a small migraine and DRY MOUTH. I forgot to mention I also had a tiny thyroid problem, which I don't have anymore, and was taking birth control pills, Slynd, for my hormones to balance, which never made me gain weight at all and never affected my health. Phentermine seems to help me with my health problems a lot. I truly recommend this pill to someone who is willing and dedicated to lose weight. This is a life changer for a better you."

10 / 10
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Frequently asked questions

  • Sam...
  • Taken for 1 to 6 months
  • May 18, 2024

For Weight Loss (Obesity/Overweight) "I am a 57-year-old nurse and my weight had increased to 224 pounds after years of menopause and management of chronic illnesses. I started taking phentermine on 12/1/23 as a low dose. I was amazed at the energy it provided me. I also incorporate exercise as it gives me the energy to exercise, a healthy diet with calorie control to 1000-1200 calories per day and daily weights. I also use MyFitnessPal and Fitbit to help log and manage my progress. Now I am almost 6 months into my journey. I have lost 45 pounds, my cholesterol and triglycerides are now normal, my blood pressure is now in low normal and beginning to wean off BP meds. I have psoriatic and rheumatoid arthritis and my pain has gone from 5-6 to 0-1 (on most days). I have experienced dry mouth, headaches, and constipation, but drinking more water, eating more fruits and vegetables, and exercise have helped all of these. Stay the course, the results are well worth it. I love the healthier and thinner me!! This medication is a lifesaver!!"

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  • Kri...
  • Taken for 6 months to 1 year
  • July 19, 2014

Phentermine for Weight Loss (Obesity/Overweight) "I started off on the highest mg, which is 37.5, and it has worked very well for me. In my first month, I had lost 26 lbs, and in 6 months, I lost a total of 90 lbs. I DID NOT EAT HEALTHY NOR DID I EXERCISE. I took a break from it a couple of months back because it's not safe to take it for an extended period of time due to the fact that it takes a toll on your liver. I just got back on it again yesterday. It will cause you to have DRY MOUTH, CONSTIPATION, URGES TO DRINK LOTS OF WATER, ENERGY, ABILITY TO STAY FOCUSED, INSOMNIA, FAST HEART RATE, MOOD SWINGS, NAUSEA, AND EASES BODY PAIN. I have a heart murmur and panic attacks, so after taking this medication, I notice it gets harder for me to breathe as the day goes by."

9 / 10
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  • 920...
  • October 25, 2009

For Weight Loss (Obesity/Overweight) "This one little pill changed my life. I weighed 208 lbs, wearing a size 18, and had tried everything to lose weight but just couldn't. My doctor, who I was working for, suggested taking phentermine and I'm so glad he did. I was losing an average of 1-2 pounds a day. I lost 65 pounds in 2 months and now wear a size 8. I have not taken the pill in the last year and did not gain any weight back. The only side effect I had was dry mouth. I can handle dry mouth for the results I got from this amazing little pill that changed my life."

10 / 10
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  • Sis...
  • Taken for less than 1 month
  • January 31, 2021

For Weight Loss (Obesity/Overweight) "I started taking 37.5 mg of phentermine - one pill in the morning. Before taking this, I had been exercising and eating right, but I could not lose a pound. Since starting phentermine a week ago, I am down 5 lbs. I am so excited! I have so much energy and no appetite. I was close to 200. I also have fibromyalgia, and it helps with that. I think they should actually prescribe it for fibromyalgia. I took Cymbalta in the past for fibromyalgia, but phentermine is so much better! I am going to hug my doctor if I reach my goal of 150. Side effects for me are dry mouth, but you end up drinking more because of it, so it isn't a bad thing. I honestly feel like this may be a miracle pill for me!"

9 / 10
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  • Sar...
  • June 21, 2016

Phentermine for Weight Loss (Obesity/Overweight) "I started Adipex on 5-23-16 exactly 4 weeks ago from today. From the first day I took it, I noticed a huge difference. I lost almost all appetite and had to force myself to eat even though I wasn't hungry. The best thing about it is when I did eat, I took the time to think about what I was putting in my body and made better and healthier choices. There are times when I wanted something I knew wasn't good for me, but my willpower is stronger and I turned from it. I drink only water. It helps me stay full. I also have been working out 2-3 times a week. The only side effect I've had was dry mouth the first week. I went to the doctor today and I've lost 23 lbs in 4 weeks. I recommend this to anyone struggling with weight loss."

10 / 10
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  • Fra...
  • Taken for 1 to 2 years
  • November 25, 2014

Phentermine for Weight Loss (Obesity/Overweight) "Adipex-P worked for me. I lost the weight and I'm keeping it off. I haven't become resistant to the medicine at all. The generic brand is different - I had a headache and dry mouth. The name brand - no problems. I'm continuing to take it under the supervision of my doctor. I have no side effects, I feel good and I'm at a good weight. I exercise and stay on a low carb/high protein diet. This medicine rescued me from the weight loss merry-go-round."

10 / 10
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  • tat...
  • Taken for 1 to 6 months
  • September 15, 2014

For Weight Loss (Obesity/Overweight) "UPDATE: Started taking phentermine on 7/18/14 and as of today 9/15/14, I'm down 32 lbs in almost 2 months. Still have dry mouth, but not as bad. Drinking 65 to 70 ounces of water a day along with a 1,800 calorie diet. No sugar, no soda, no fast food. Everything fresh and baked, not fried. More updates next month."

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  • tur...
  • Taken for less than 1 month
  • February 24, 2015

For Weight Loss (Obesity/Overweight) "I started my pills Phentermine 37.5 mg on Feb 18, 2015. At 337.2 lbs on that day. As of today, Feb 24, 2015, I am 319.4 lbs, 17.8 lbs lost. The only side effect is dry mouth, so I'm drinking plenty of water. I also take Xenical 120 mg, one capsule half an hour after my last meal of the day, at 8:30 pm. My weight goal is to get down to 250 lbs, and once I hit that goal, I will set my goal to 225 lbs, going one step at a time. I'm proud of all of you, keep up the good work."

10 / 10
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  • Nor...
  • June 3, 2020

For Weight Loss (Obesity/Overweight) "5'11 and I weigh 170, yes I'm tall but this is the heaviest I've been and I'm not happy with it. Side effects: no sleep, lower back aches, dry mouth, made me angry which I'm never angry. Also here and there a little depressed. But I would have to snap out of it very quickly. But overall it's a good pill to take if you have self-control and you won't get addicted to it. It gives you lots of energy which I like to work out in the gym or go for a jog at a park. You will lose weight quickly but you have to maintain it. I have a sweet tooth so I would eat chocolate after I lost all my weight then I would see I gained weight like 2 lbs and I would work out the next day. You have to be consistent and dedicated."

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  • Dra...
  • Taken for less than 1 month
  • August 25, 2014

Phentermine for Weight Loss (Obesity/Overweight) "I started Adipex on 8-18-14, and today is 8-25-14. I am down 8 pounds in a week. I hope this kind of weight loss continues, but I'll have to wait and see. I did experience a little bit of nausea for the first few days, but it wasn't too bad, and dry mouth a little. So far I am pretty pleased."

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  • Sho...
  • Taken for 1 to 6 months
  • March 27, 2014

Phentermine for Weight Loss (Obesity/Overweight) "I started on Adipex on Feb 16th. I weighed in at 308 lbs, the heaviest I've ever been. As of March 27th, I am now 260 lbs and going. I run 5 miles every day and have totally changed my lifestyle. Drinking lots of water, I probably go through a case and a half a week. I did experience dry mouth and a serious boost of energy the first day I took it. After that, it's just been dry mouth but hey, I'm accustomed to drinking a ton of water. If you change your lifestyle and hit the gym, it works."

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  • cwa...
  • February 3, 2021

For Weight Loss (Obesity/Overweight) "I went to a weight loss clinic on January 4, 2021. The doctor put me on an old-fashioned low-fat diet and phentermine. Wow! I went from 218 lbs on January 4 to 210 lbs this morning. The dry mouth is lessening. No more jitters or anxiety. I really don't think about food. The doctor told me not to spend too much time in the gym because I am not training for athletics, and most people get into routines they will not sustain. He told me to walk a bit every day and to continue my yoga daily, even if for just 15 minutes. I take trazodone for sleeplessness. It's not a sleeping pill but an antidepressant. It doesn't have the harmful side effects of regular sleeping pills. When combined with melatonin, it really helps. I don't take phentermine every day. I think it accumulates in my system and keeps me awake unless I mix it up a bit. Some days I take half a dose, and today I took none. I believe I will sleep better tonight and still get the benefits of a reduced appetite."

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  • Chu...
  • Taken for less than 1 month
  • February 21, 2020

For Weight Loss (Obesity/Overweight) "My body demographics: age 28, 5’1”, Starting weight as of 2/18 was 180lbs. I breastfed my child til 10mo then instantly gained 30lbs after I stopped (warning to all breastfeeding moms!). I would exercise, went on every extreme diet you could think of for weeks and sometimes months at a time, and usually could only manage to shake about 2lbs. After just three doses of this medicine, I’m already down 6lbs. Yes, there are side effects, but it’s worth it to me. I definitely have the dry mouth and headaches, but it makes me drink more water. I was incredibly addicted to Mt. Dew. Since I’ve started, all I want is water. I hardly have an appetite. I eat less than half of what I had been. It’s a miracle in pill form!"

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  • Blo...
  • January 28, 2020

Phentermine for Weight Loss (Obesity/Overweight) "I have been on Adipex for two weeks. My doctor suggested it to help me lose some weight. I was 200 pounds at the start. I am now 194 lbs after 2 weeks. I take a half pill a day. I work at a desk all day and would have issues with snacking all afternoon. Now I don't. I force myself to eat some fruit every afternoon or a protein shake. I can't eat a full meal because I feel fuller faster. I have more energy. I have had dry mouth, but drinking water is a big help with that, and I drink a lot more water. I do have some heart racing at times, but the more water I drink, the better that is, which is good because it did throw me into a few panic attacks. No headaches. I did get insomnia the first two nights, but I switched to taking the pill at 10 am instead of noon and that stopped. I started exercising so hope to see more weight drop off. My goal weight is 145, but I am only taking this until my bottle is gone."

8 / 10
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  • Lad...
  • July 13, 2021

For Weight Loss (Obesity/Overweight) "Taking this medication for 4 months now, I was 203 pounds in March and down to 169 pounds now (July), feeling good. I'm 33 years old, I've always struggled with my weight and binge eating disorder, but it got worse during the pandemic. I was binge eating every day, and I couldn't control it - I was 203 pounds, the heaviest I've ever gotten. I was uncomfortable in my own skin, so I decided to look for help because I couldn't do it on my own, even though I tried. The doctor prescribed phentermine. It took away most of my appetite and cravings - I felt hungry, but I would eat just the necessary. I still have binge eating episodes when I have PMS, but not as bad as before. Not many side effects for me, just a VERY dry mouth, it made me drink more water, which is good. I experienced insomnia sometimes, and a little headache and constipation in the first week. I recommend it to people who want to get healthier but can't do it alone, just don't forget that you have to be strong to keep the results. It's not a miracle pill."

10 / 10
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  • Chi...
  • Taken for less than 1 month
  • July 17, 2014

Phentermine for Weight Loss (Obesity/Overweight) "I started taking Adipex on July 15, and I must say I have definitely seen a difference in my eating habits and it's only been 3 days! Amazing! I was 127 lbs in 2012 and somewhere along the line I lost the will to work out and stay fit. Needless to say, I gained about 35 lbs since then. So, I am giving Adipex a try, and it's doing wonders for my appetite! I experienced dry mouth the first day, and that's the only side effect I have had. I eat yogurt for lunch, and dinner is 2 turkey sandwiches on wheat bread, and I drink 2-3 bottles of water a day. Eating right and exercise are key to helping drop weight quicker! Once you stop taking the pill, you must maintain good eating habits along with exercise, or the weight will come back plus more!"

9 / 10
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  • big...
  • Taken for less than 1 month
  • November 12, 2013

Phentermine for Weight Loss (Obesity/Overweight) "I just started Adipex 3 days ago. I'm having some insomnia and terrible dry mouth. But I also have mad energy and a little appetite. Adipex is amazing! Compared to having no energy, terrible depression, and feeling like there was no hope, I feel great! Hopefully, this continues - don't give up, there is help out there!"

10 / 10
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  • Kor...
  • May 5, 2014

Phentermine for Weight Loss (Obesity/Overweight) "I've been taking Adipex capsules for 1 week now and I am down 11 pounds. I don't exercise. The pill just makes me not want to eat. I have to make myself eat. I also have severe dry mouth, so I drink water way more now. The only other side effect I have is heart flutters. But I can handle that, because it happened to me before I was on Adipex."

10 / 10
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  • Bob...
  • Taken for 1 to 6 months
  • December 30, 2020

For Weight Loss (Obesity/Overweight) "I’m 62 and a veteran. I have always been active. I started slowing down a bit and gained some weight. I’m diabetic and have tried to lose weight. I’m 5 ft 8 in and weighed 240 lbs. I went on a 1200 calorie diet for 3 months and lost 10 lbs. I leveled out. I went to see my PCP for some help. He put me on phentermine 30 mg per day. Wow, in 2 months I have lost 24 lbs and eat like a bird. I have a salad and I am full for the day. I still walk and stay busy. I am retired because I am disabled. My desire for food is almost zero. I feel much better, my blood sugar is way down. You have to drink lots of water on this medication. Dry mouth is always there. I have to keep going, and I plan to. For my family. God bless."

10 / 10
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  • jes...
  • Taken for 1 to 6 months
  • December 12, 2013

Phentermine for Weight Loss (Obesity/Overweight) "I started taking Adipex in Sept and went in on Dec 7th for my three-month check-in, and I lost 38 pounds. I am 5'8'' and began weighing in at 259, and now I'm down to 221, and this is without including exercise. Walking is part of my daily routine, I walk a lot throughout the day as I'm running between classes and then to go to work. I did experience some side effects the first week, like being lightheaded, dizziness, and a dry mouth. But I use that to increase my water intake. My doctor actually recommended I only take it about 5 days a week so that my body doesn't become so used to it, and that's what I have been doing. So far, so good, and I can't wait to continue losing weight."

10 / 10
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  • Att...
  • Taken for 1 to 6 months
  • December 22, 2014

Phentermine for Weight Loss (Obesity/Overweight) "I was prescribed Adipex on Nov 10, 2014. I weighed 155 pounds. To some that might not seem like a lot, but it was to me. I had tried working out and eating right, and nothing was helping. Today, Dec 22, I weighed 135. I have steadily lost weight since starting it. I skip some days and still feel energetic and not as hungry. The first week on Adipex, I had the worst dry mouth. I couldn't drink enough water. I'm still pretty thirsty, but it's manageable. Drinking water helps the medicine work better. I have also changed my eating habits to use when the pills are up. The first night I didn't sleep, but now I can go to bed no problem. This medication isn't a quick fix, it simply is helping you make lifestyle changes to keep weight off."

10 / 10
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  • taz...
  • Taken for 2 to 5 years
  • May 31, 2024

For Weight Loss (Obesity/Overweight) "I took this medication years ago for weight loss. It became my best friend; I had energy and was able to pass on foods that normally found their way into my mouth. I did experience dry mouth, and this was even with taking copious amounts of water. I went from 303 lbs. down to 245. It did take about a year to lose this weight even with exercising 3 to 4 times a week doing cardio and various exercises. After a year, my doctor removed me from the medicine. I did keep the weight off for a bit but did gain all the weight back. (Divorce, life changes, and COVID did not help since food had always been my comfort.) Fast forward 5 1/2 years, and I went back on the medication again. Weight loss has been slow (maybe due to age and menopause). I have been on it again for 5 months and lost 35 lbs., which is about 7 lbs. a month. I know not huge losses, but it does help suppress the appetite, and I still have dry mouth. I do have more energy but not like the first time taking this medication."

8 / 10
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