Skip to main content

Zofran and Diarrhea: What Users Say

Diarrhea: mentioned by 5 users (1.8%)

Based on user experiences from 271 Zofran reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 21.4%
vomiting 15.1%
constipation 12.5%
headaches 7.7%
dizziness 5.5%
drowsiness 3.3%
tiredness 2.2%
diarrhea 1.8%
sleepy 1.8%
tremors 1.5%

Reviews for Zofran

Commonly mentioned side effects
  • Sug...
  • Taken for 6 months to 1 year
  • October 6, 2019

For Nausea/Vomiting "I have several chronic conditions, and one is called Cyclic Vomiting Syndrome. It's even worse than it sounds. I'm over 40 and have suffered since childhood. Gravol stopped working over a decade ago. Last December was particularly bad with many trips to the ER, and I finally got lucky and was given this. It's a miracle drug for me about 95% of the time. I do get some side effects like diarrhea and sweating, but they're very bearable. I don't go anywhere without a bottle of these."

10 / 10
Was this helpful?YesNo
21 Report
  • Anonymous
  • April 10, 2009

For Nausea/Vomiting "I was given Zofran for all-day morning sickness during pregnancy. It works very well, but causes constipation, stomach cramps, and diarrhea. If I wait at least 12 or more hours between doses, the side effects are milder and the nausea is almost completely gone. Before I had this drug, I was miserable and missing work."

9 / 10
Was this helpful?YesNo
20 Report
  • mar...
  • Taken for less than 1 month
  • January 12, 2019

For Nausea/Vomiting "I have had severe nausea and vomiting 2 times in 2 weeks from eating seafood, so I'm guessing no more seafood. The nausea stopped after taking 2 pills. Threw up the first time, then the second one stopped it within 20 min. I'm so happy. The first time I had nausea, vomiting, and diarrhea for 5 hours, had to go to the emergency room. Once diarrhea stopped, they gave me this medication, and all stopped."

10 / 10
Was this helpful?YesNo
8 Report

Frequently asked questions

  • Vin...
  • Taken for 1 to 6 months
  • September 7, 2018

For Nausea/Vomiting "I take another drug that causes severe nausea. Zofran was prescribed; the nausea stopped, but the other side effects from Zofran were so overwhelming that I had to stop taking it. The side effects were diarrhea, headaches, blood in stool, dizziness, and yes, nausea. I couldn't drive, so I'll live with the nausea until I see my endocrinologist again and (maybe) he suggests something else. Bottom line: the side effects of Zofran outweigh the benefits."

4 / 10
Was this helpful?YesNo
6 Report
  • Gee...
  • Taken for 1 to 6 months
  • December 13, 2020

For Nausea/Vomiting "I was warned of the possibility of severe vomiting/diarrhea due to chemotherapy for treatment of Glioblastoma. I have 10 days left on treatment, and so far, no side effects at all!"

10 / 10
Was this helpful?YesNo
14 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.