Zofran Alternatives Compared
| Zofran (ondansetron) | Ondansetron | Promethazine |
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| Zofran (ondansetron) | Ondansetron | Promethazine |
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Prescription only
Zofran is used to prevent nausea and vomiting caused by cancer chemotherapy, radiotherapy, or surgery. It is approved for use in adults and children over the age of 4 and is available as tablets... View more |
Prescription only
Ondansetron may be used for the prevention or treatment of nausea and vomiting but it may cause constipation or a headache. Prescribed for Nausea/Vomiting, Gastroenteritis, Nausea/Vomiting -... View more |
Prescription only
Promethazine may be used to relieve allergy symptoms and nausea. Sedation is the main side effect and it may interact with several other drugs including antidepressants, antipsychotics, and other... View more |
Related suggestions Nausea/Vomiting
Popular comparisons
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| More about Zofran (ondansetron) | More about Ondansetron | More about Promethazine | ||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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Zofran has an average rating of 8.0 out of 10 from a total of 271 ratings on Drugs.com. 76% of reviewers reported a positive effect, while 15% reported a negative effect. |
Ondansetron has an average rating of 7.8 out of 10 from a total of 496 ratings on Drugs.com. 73% of reviewers reported a positive effect, while 18% reported a negative effect. |
Promethazine has an average rating of 7.2 out of 10 from a total of 389 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 21% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||
View all Zofran side effects |
View all Ondansetron side effects |
View all Promethazine side effects |
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| Drug Class | ||||||||||||||||||
| Generic Availability | ||||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Ondansetron prices |
View all Promethazine prices |
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| Dosage Forms | ||||||||||||||||||
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| Brand Names | ||||||||||||||||||
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N/A |
N/A |
Adgan, Anergan 50, Antinaus 50, Phenadoz, Promethegan | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||
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4 hours |
4 hours |
16 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 358 drugs are known to interact with Zofran:
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A total of 358 drugs are known to interact with Ondansetron:
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A total of 688 drugs are known to interact with Promethazine:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||
| First Approval Date | ||||||||||||||||||
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December 31, 1992 |
January 04, 1991 |
March 29, 1951 |
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| WADA Class View classifications | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||
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| Professional Resources | ||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.