Lupron Depot for Endometriosis User Reviews (Page 2)

• Anonymous
• March 26, 2009

"I am on my 2nd shot of Lupron and I am not liking the new me. Everyone says after the first 6 weeks it gets better. I don't know if I can take anymore or if anyone else can take my mood swings. I am very hormonal, frustrated all the time and mad about everything. My job and family are suffering. The hot flashes are constant I am miserable. I don't think I will continue with the other shots."

• India...
• March 4, 2008

"The shot is not too bad in the butt cheek. My problems were the side effects. I think that the hot flashes are the worst of it. I am on my 5th shot, and now I am going through a lot of mood swings as well."

• Melissa
• September 27, 2018

" I had severe cervical dysplasia requiring a portion of my cervix be removed, chronic pain, PCOS, and was diagnosed with severe endometriosis following laproscopic removal of many adhesions from my uterus and scarring of my ovaries. My OB recommended I do six to nine months of Depot lupron after my laproscopy to keep the Endo at bay and help reduce scarring. I started out with the one month shot and felt okay, a little achey and some hot flashes. I went back to got the three month shot. I was miserable but my OB really pushed me to keep going with it. I am on my second three month shot and I am not me anymore. I am moody, extremely depressed, my bones hurt, I've gained 20lbs, I'm fatigued, anxious, have insomnia, headaches, and have had horrible gastrointestinal symptoms. It is ruining my marriage. My work performance has suffered. I am foggy and forgetful. Everything is an effort. I will not be getting the last shot and hope this hasn't caused irreversible damage!!!"

• EJoy
• Taken for 2 to 5 years
• July 27, 2012

"6 years ago I experienced severe pain caused by ovarian cyst and endometriosis. I eventually had my cyst out but after few months severe pain triggered. I was dying of pain most of the time, until such time I cannot tolerate. August 2008 I was given Lupron Depot. First month was a nightmare for me, I thought I was dying because of extreme bleeding. After that one month my body slowly progress. For three months I had a 3.75mg and after that I was having 11.25mg. I am so relieved that it made me live a normal life. I am pain free and for side effects fortunately not too the extreme. My last shot was done March and supposed to have it last June but due to unavailability of my specialist I am waiting for my next step. So far I am doing fine."

• barbe...
• October 30, 2013

"Feb this year I had an Ovarian cyst on my right overie rupture , it was the size of my 3yr olds head. When they operated they found I was covered with Endo... ah finally a reason for my pain for the last 2years... I have just finished my 6 month course. Endo pain fine but OMG the side affects, dealt with hourly hot flushes home and at work.. gained 10kgs (awesome) but the mood swings REOW!! my poor partner. Lucky he is amazing... No pain yet but have to wait and see whats next. Maybe Mirena."

• Me2
• August 31, 2018

"Took the 3 month lupron depot shot just one time. It's now 3 months since I had the shot, my reasons for taking this poison is due to extreme PMDD condition, which I also have endo, but the PMDD outweighs! So all my symptoms since the very 1st week of the injection have been severe hot flashes, night sweats, more fatigue-whole body aches. Just in the last month my hair has been falling out! Very dry, thin now- I'm extremely moodier than before, This was the worst thing I've done & I'm super mad at all these doctors who really have no clue what they're doing to people. We are all their guinea pigs. I went 4 days ago to the doctor & he put me on premaire ( hormone replacement). I'm waiting in misery to see if this added med helps. So far- the new med has had me in tears everyday for no reason, a massive migraine and overall loosing my mind! Never ever take lupron! Just do an internet search on lupron victims."

• Anonymous
• April 3, 2012

"I got my first dose a month ago. The main side effects I am experiencing are hot flashes, much decreased appetite (not complaining there) and fatigue. I will take all those any day rather than deal with endometriosis pain. So I am definitely pleased with the Lupron treatment. Its nice to not be in so much pain. I would call off work and stay in bed and cry. So big difference!"

• Alma...
• Taken for 1 to 6 months
• October 30, 2016

"This drug ruined 11 years of my life & continues to do so. I was given no addback therapy, nor told of any side effects, only the leaflet to read at home AFTER I'd already been given 3 month Lupron shot & told it will help my excruciating Endometriosis pain. After reading leaflet in it's entirety I immediately called my OB/GYN & asked about addback, Calcium & lots more questions. I was scared of all side-effects listed on the leaflet & wished I had known about them before (I'd have refused) or that I could UNDO the shot! He told me worst that may happen are few hot flashes. My pain worsened, I got OSTEOPOROSIS, lost several teeth & couldn't walk unasisted for 6mths. THIS IS TRULY A HORRIBLE DRUG!!!"

• Stefd
• Taken for 1 to 6 months
• October 29, 2015

"My doctor has me on the six-month regimen. I am on my second month and have had to go to the ER five times since getting this injection. I don't recommend this to anyone I feel ill all the time. Very lethargic, very short of breath, heaviness in the chest, pains in my back and just overall horrible. I had my right ovary and fallopian tube removed due to severe endometriosis and the doctor recommended these injections and said I would have no problem and no buddy that she has treated his head any severe side effects so I guess I get them all. I've missed a lot of work almost losing my job because I just can't function on a day-to-day basis because of the medication. For any of you considering taking this medication please don't it is nothing but toxic"

• DanniKJ
• Taken for 1 to 6 months
• April 27, 2012

"2/9/12 I had a full hysterectomy (uterus and cervix removed) due to fibroids. My Dr found endometriosis everywhere. My Dr. put me on Lupron about a month after the surgery and I had my 2nd shot 4/20/12. I got hot flashes right after the first shot but they are really not that bad. Night sweats are more uncomfortable and my joints and muscles are achy and stiff. However, my mood is pretty terrible. I have no patience for anything and feel pretty grumpy most of the time. My pain is lessening but still present. That said, if I can be rid of most of the pain after the 6 months regimen, it will have been worth it! "

• Anonymous
• Taken for less than 1 month
• June 9, 2012

"I received my first Lupron shot a couple weeks ago. In the past two weeks I have noticed that my pain isn't as bad or as often and it was before the shot. The down side is the mood swings and hot flashes. I thought I had a few weeks before I started experiencing the side effects, but I guess not. I know that the next six months are going to be rough, but the way I see it...I've been suffering for five years already, what is six months of hell to help make it all go away? In my opinion, the Lupron shot is worth it."

• Kathy
• Taken for 1 to 2 years
• March 8, 2018

"I have been on the Lupron for about a year. Last year I had 6 monthly injections. The pain that I was experiencing before taking Lupron was horrible. Within 3 weeks of being on Lupron I was pain free with very minimal side effects. One of them was weight gain. For me the weight gain was way better than the pain that I was experiencing before! I went off the shot for about 6 months and the pain returned. The second time around I received a 3-month injection. The pain got worse the first couple of weeks then it was gone again. Now I feel like I can live a normal pain free life again. Still very minimal side effect. This drug has been a life saver for me! I read so many horrible reviews of this drug but honestly its been a huge relief for me!!! I now can function again!"

• julrez
• October 6, 2015

"I've been suffering with very painful mensuration and chronic pelvic spasms for over 20 years. The first time I did Lupron is was a god sent, finally I didn't have to plan my life and work around my period. Now I'm on a second round. I'm using the 3-month injection and I love life. Yes, I have hot flashes and I can be a bit emotional at times, but I'm not in pain and that is what I was going for. I'm 42 now, and I'm hoping I can stay on this medication, until I'm 50. I would really hate to go back to having to deal with this again."

• Liebora
• January 19, 2016

"The side-effects have lasted years and Lupron itself caused depression. And I gained over 40 pounds rapidly within three months after use. It gave me seizures, and I had blackouts on TOP of the usual side-effects. I was hospitalized for three days because of the seizures. NOT worth it! I'm still plagued by the ungodly side-effects every single day! Worst decision I ever made. NEVER again!"

• eab
• Taken for less than 1 month
• August 11, 2018

"Only a few weeks in and I already hate this. I’m 19 and was diagnosed with stage 4 endometriosis. My doctor said the Lupron shot is my only option in regards for treatment, before a hysterectomy. I’ve been on birth control for 5 years prior for intense pain but it didn’t help at all. 2 weeks in, my bones hurt, I’m constantly hot and nauseous. Depression I feel is on its way. I can’t stop crying and I feel very sad about life. Which is unlike me, I’m a very positive person. My pain is also more intense than before. I feel very helpless because I don’t want to have a hysterectomy at 19 but I hate this medication already. I don’t know what else to do"

• Anonymous
• March 6, 2010

"At first I really thought the Lupron treatments where worth it, but now that I have made a trip to the Emergency Room. Well lets just say if you are going to go the route of Lupron you better be single. This drug takes its toll on the family, not just you. Everyone goes throw the mood swings, headaches, blood pressure scares, joint pain, feeling like you are going to pass out. So no taking your kids to school or sporting events. No joining car pools. Don't get to far away from the restroom, urinating more often is not unusual. The things that are the easiest to handle are the hot flashes, night sweats and chills."

• Anonymous
• December 21, 2011

"I was actually surprised to learn I had stage 4 endometriosis along with 2 endometrioma's and a dermoid cyst. I had always had a poochy gut and severe menstrual cramps since I was 16. I am 27 now and have been pain free for the last 5 months on Lupron Depot. I had a laproscopic cystectomy and a laparotomy this year. I did suffer side effects of hot flashes and mood swings but was prescribed 1mg estrogen daily and I'm pretty much normal! In about 6 weeks I will begin trying to conceive my first child! The Lupron and my Doctor have been a blessing!"

• KC813
• April 3, 2016

"I want to share my experience with this drug because I truly believe it's of utter importance. My first BC was Depo PROVERA. I bled right through this, and yes it's common for the first year, also lighter periods. But mine never went away, then brown bleeding. I was switched to the implant, for other reasons, and the same problem still occurred. Then I was put on BC pills to control the bleeding process. All in all, I was backing up my uterine wall with more blood every time I had a period. Depo Lupron was injected on Jan 18 I bled out all my old blood in a week. I have not had a period or brown bleeding since. My last shot was given March 18. So far, 0 breakthrough bleeding. I love Depo Lupron"

• Anonymous
• Taken for less than 1 month
• October 20, 2012

"I am only on one week into the Lupron and my pain has begun to, not ease, but not be as sharp as it was at all times. I can finally breathe and think before the next stabbing pains begin. But about two days ago I got mood swings. I seem insane, I'm fine then, I'm screaming. I'm only 17 and this is NOT what I need along with the disease. I hope it gets better for I wont have any friends at the end of the six months."

• Sweet...
• January 6, 2017

"I was diagnosed with stage 1 endometriosis after I had a laparoscopy. My doctor suggested lupron depot for six months (2 shots). I have been on lupron depot for almost 3 months where it is time to get my second shot. I am almost sure I will not get the second shot. I am in worst pain than I was before the shot and I have had NON STOP bleeding. You are not supposed to be bleeding while on lupron especially for three months. I have an appointment with my doctor soon about my next step. The medicine is supposed to rid you from pain-but for me it caused it to worsen. In regards to other side effects such as hot flashes, depression, mood swings, etc I don't have any of that! Bottom line, I wish I never would have got this medicine."

• Miser...
• July 24, 2009

"I took my first injection 4 days ago, but had a migraine that night. Since then I have been crying a lot. I can't believe the side effects have hit me so fast. I have abdominal pain as well but the crying is the worst so far."

• crazyme
• June 10, 2015

"I am very happy I went on Lupron Depot. I am on my 6th month of it and although the symptoms of hot flashes, night sweats, moodiness, and some weight gain are not fun, it still is VERY worth it. I have been pain free (when I was in debilitating pain before) and no period which is nice. Hopefully I'll be able to get pregnant soon too!"

• Steph...
• December 21, 2019

"I have stage 4 endometriosis and adenomyosis. Had emergency surgery 3 years ago due to a large endometrioma causing a total blockage of my sigmoid colon. Everyone's reports on here about unbearable pain and severe bleeding - yup, same for me. I've been bleeding nonstop for over a year now. Received my first 1 month dose of lupron on 11/22/19. The only side effect was a slight uptick in libido the first two weeks during the initial estrogen spike. The last week of the month, I got my period but the bleeding and pain were much reduced from before. Noticed an improvement in pain during intercourse. I am on the add-back and have had no night sweats, hot flashes, or vaginal dryness. No impact on my mood that I could notice. Received my second dose, the 3 month long dose, yesterday (12/20/19). Can't comment yet on the experience, but I'm sure hoping to stop bleeding entirely and eliminate the pain."

• Lala
• November 5, 2018

"I will say I virtually have no periods and have had maybe 3 endo pain days that don’t come close to what the pain used to be. NOW the side effects are horrid! BUT I’ll take the side effects over the pain in periods. My bones ache not unbearable but uncomfortable. The night sweats bad but bearable. I’m tired lots but I can function with some caffeinated tea & b12 for energy. Mood swings and little depression/anxiety. It’s not intense depression for me like nothing that makes me want to harm myself it’s just more of a dark cloud following you around. So if you have mental “instability” before taking the drugs make sure you talk to your doctor. I did not lose hair and my hair did NOT thin/fall out. I did not gain weight. The side effects still make the medicine worth taking because I have no pain or real periods. I get the shot every 3 months (I’m on 9 months) and take a pill that comes in the shot package. The pill is taken daily, shot is every 3 months for me. Goodluck!"

• Ei...
• December 7, 2016

"I have endometriosis and adenomyosis and pain was scary and I became bedridden some of the days.I had my first Lupron 11.25 mg on June 2016.I am suffering following side effects but I will continue this medication as pain from endo and adeno is worse then side effects. - Swelling at feet - Weight gain - 6kg in 6 months - Increased sweating - Hot flash suffered only first month of this treatment - Fluid retention - Carpal tunnel - Forgetful - Growth of upper lip hair - Slipped disc and compress of the right leg nerves I am going to take second injection soon and after that I will go for Hysterectomy. Btw I am just 36:(."