Lupron Depot Alternatives Compared
| Lupron Depot (leuprolide) | Norethindrone | Orilissa (elagolix) |
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| Lupron Depot (leuprolide) | Norethindrone | Orilissa (elagolix) |
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Prescription only
Lupron Depot is a hormone deprivation treatment that may be used for the palliative care of advanced prostate cancer. The main side effects are hot flashes and general pain and it may cause... View more |
Prescription only
Prescribed for Abnormal Uterine Bleeding, Endometriosis, Amenorrhea, Gender Affirming Hormone Therapy , Birth Control. Norethindrone may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Endometriosis. Orilissa may also be used for purposes not listed in this medication guide. |
Related suggestions |
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| More about Lupron Depot (leuprolide) | More about Norethindrone | More about Orilissa (elagolix) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Lupron Depot has an average rating of 5.9 out of 10 from a total of 231 ratings on Drugs.com. 45% of reviewers reported a positive effect, while 31% reported a negative effect. |
Norethindrone has an average rating of 4.9 out of 10 from a total of 1570 ratings on Drugs.com. 33% of reviewers reported a positive effect, while 45% reported a negative effect. |
Orilissa has an average rating of 5.4 out of 10 from a total of 128 ratings on Drugs.com. 41% of reviewers reported a positive effect, while 40% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Lupron Depot side effects |
View all Norethindrone side effects |
View all Orilissa side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Lupron Depot prices |
View all Norethindrone prices |
View all Orilissa prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Other leuprolide brands include: Camcevi, Eligard, Fensolvi, Lupron, Lupron Depot-PED | Affodel, Camila, Deblitane, Emzahh, Errin, Gallifrey, Heather, Incassia, Jencycla, Lyleq, Lyza, Nor-QD, Norlyda, Norlyroc, Orquidea, Sharobel, Tulana View more |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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4.25 hours |
10 hours |
6 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 281 drugs are known to interact with Lupron Depot:
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A total of 262 drugs are known to interact with Norethindrone:
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A total of 369 drugs are known to interact with Orilissa:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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January 26, 1989 |
April 21, 1982 |
July 23, 2018 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.