Comparing Depo Provera vs Lupron Depot
| Depo Provera (medroxyprogesterone) | Lupron Depot (leuprolide) |
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| Depo Provera (medroxyprogesterone) | Lupron Depot (leuprolide) |
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Prescription only
Prescribed for Birth Control. Depo Provera may also be used for purposes not listed in this medication guide. |
Prescription only
Lupron Depot is a hormone deprivation treatment that may be used for the palliative care of advanced prostate cancer. The main side effects are hot flashes and general pain and it may cause... View more |
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| More about Depo Provera (medroxyprogesterone) | More about Lupron Depot (leuprolide) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Depo Provera has an average rating of 4.2 out of 10 from a total of 1967 ratings on Drugs.com. 27% of reviewers reported a positive effect, while 55% reported a negative effect. |
Lupron Depot has an average rating of 5.8 out of 10 from a total of 231 ratings on Drugs.com. 44% of reviewers reported a positive effect, while 32% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Depo Provera side effects |
View all Lupron Depot side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Depo Provera prices |
View all Lupron Depot prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other medroxyprogesterone brands include: depo-subQ provera 104, Provera | Other leuprolide brands include: Camcevi, Eligard, Fensolvi, Lupron, Lupron Depot-PED, Lutrate Depot | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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401 hours |
4.25 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 248 drugs are known to interact with Depo Provera:
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A total of 282 drugs are known to interact with Lupron Depot:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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September 23, 1960 |
January 26, 1989 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.