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Clomiphene and Headaches: What Users Say

Brand names: Clomid

Headaches: mentioned by 9 users (3.4%)

Based on user experiences from 263 Clomiphene reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

hot flashes 4.2%
mood swings 3.8%
cramps 3.4%
headaches 3.4%
miscarriage 2.3%
sore breasts 2.3%
back pain 1.9%
bloating 1.9%
fatigue 1.9%
flushing 1.9%

Reviews for Clomiphene

Commonly mentioned side effects
  • Lil...
  • Taken for less than 1 month
  • October 13, 2020

For Ovulation Induction "I just completed my first 5-day cycle of Clomid. My story is a little different than most I’ve read, I have pretty regular periods and I do ovulate, but I keep having miscarriages, and now since my last one in January, I am now having trouble getting pregnant. My doctor prescribed I take it starting on day 5 of my menstrual cycle. No bad side effects, I did have a headache and a little fatigue. Now I go back to my doctor on Friday for an ultrasound, not really sure what to expect. I’m so intrigued. I’m really hoping we get pregnant. Praying for everyone’s success with Clomid and healthy, happy babies. Thanks for listening."

6 / 10
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55 Report
  • Shi...
  • Taken for 1 to 6 months
  • March 9, 2020

For Female Infertility "I’ve been trying on and off to get pregnant for about 18 years, gone through extensive tests, diagnosed with PCOS, and the only thing they told me to do was lose weight. I tried keto and lost weight, then life happened and fell off the keto train, then moved to Texas, and the doctor gave me 3 cycles of 50 mg Clomid. I’m on my first cycle, right after the last pill, I had a headache for 3 days straight, and I took it at night to avoid the symptoms, but got bloating still. I tracked ovulation with OPKs and ovulated on cycle day 20, used pressed, and I’ve been taking prenatal. Fingers crossed."

7 / 10
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36 Report
  • dan...
  • September 13, 2016

For Female Infertility "My fiancé and I have been trying to conceive for four years. We are both 26 years old. Last year I was rushed into emergency surgery because I had cancerous cysts on my right ovary and cysts that had burst. After the procedure was done, my doctor told me that my left ovary didn't work. It wasn't producing anything. So, he told me that the cancerous cysts were probably the cause of why we hadn't gotten pregnant yet, and if in a year we still weren't pregnant to come back in. Well, one year went by and nothing. So, he prescribed me Clomid and told me to take it day 1 of my period for 5 days. I am currently on day 4/5 and have had no serious side effects besides a minor headache that goes away with Tylenol. I am so excited to see if this works!"

10 / 10
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42 Report

Frequently asked questions

  • Lam...
  • Taken for less than 1 month
  • February 6, 2022

For Female Infertility "Had a missed miscarriage at 10 weeks, and it’s been 8 months trying to get pregnant again. Started Clomid 50 mg, didn’t get pregnant. I stopped for a month and started another dose of 100 mg on January 12th to 16th. My side effects were mood swings, hot flashes, and mild headache, which stopped after the last Clomid. Well, I am on cycle day 28, been having period-like cramps, sore and bigger nipples, always horny, a bit of fatigue, which makes me a little lazy. I pray I get a positive test this time. Baby dust to us all."

8 / 10
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  • Noz...
  • Taken for less than 1 month
  • November 14, 2020

For Ovulation Induction "I'm using Clomid for the second time now for IVF. The first time we used it to produce lots of healthy eggs for IVF. That was a success, but the IVF didn't take. Now, two years later I have one open tube and the doctor gave me Clomid to ensure I ovulate on my open side. I'm on day two now. Minor headache, but nothing worrisome. I'm hopeful I'll have some good news in a couple of weeks. Hubby and I have been TTC for a year and a half now."

10 / 10
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5 Report

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  • Jew...
  • February 8, 2021

For Ovulation Induction "I first took Clomid 50 mg in December, and I unfortunately didn’t respond. I took Clomid 100 mg this cycle and now just waiting for the results of it. Side effects: cramps, headache, hormonal mood swings."

6 / 10
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5 Report
  • Nik...
  • Taken for less than 1 month
  • October 24, 2024

For Ovulation Induction "My husband and I are both 35 and have been trying to conceive naturally for 7 months. He has a low sperm count, I have irregular cycles or heavy ones. So my doctor put me on Clomid 50 mg for 5 days, took my first round on day 4 of my cycle, and finished the first round. We are now trying each and every day. Symptoms I've had are hot flushes, mood swings, fatigue, slight headaches, and now and then stomach cramps. I have lower back pain, started to get pimples, and started to get hunger pains in the morning. Later, after eating, I still feel hungry (don't know if that's normal). Today is the 8th day after my cycle, and my next period, according to my calendar, starts 22 days from now. I'm really hoping and praying that we conceive on the first round and miss my cycle. We really want our first baby, and I want to surprise him with a positive result. Any advice and tips on symptoms from the medicine and after taking it on the first go?"

7 / 10
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  • PCO...
  • October 18, 2019

For Female Infertility "It's day two of my cycle, and I took my first 50mg dose of Clomid (to help my fertility) this evening at 7 pm. I plan on taking all 5 tablets at the same time. It's reassuring reading your reviews and success stories, so I thought I would document my journey. I do have a slight headache and lightheadedness, but I have read this is normal. I will try to keep you posted on positive OPKs and whether it will be AF or BFP."

6 / 10
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7 Report
  • Twi...
  • July 17, 2020

For Female Infertility "I have endometriosis and polycystic ovaries. I have started Clomid 100 mg day one day. I’m nervous and have a headache. I also started metformin a few days ago. Don’t know what to expect."

5 / 10
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23 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.