Rexulti for Depression User Reviews (Page 5)

• Lol...
• Taken for 1 to 6 months
• October 19, 2021

"Rexulti was added as a booster to my Trintellix. Once it was added, I gained 42 lbs in 4 months without changing my lifestyle. It was the worst time in my life. Obviously, meds are a decision that a doctor should help you make, but I would avoid this drug. Once I got off of both of those drugs, I got a new psychiatrist and started taking Wellbutrin. The 42 lbs came right off and my depression was so much better."

• Blu...
• Taken for 1 to 6 months
• January 30, 2018

"I've had a good experience with Rexulti. I am struggling with depression at the moment (although diagnosed as bipolar). At first, it gave me headaches and an upset stomach. That lasted for a few days. After that, I started feeling so much better. The depression has lifted in about a week and a half to two weeks. No anxiety from this drug. No awful side effects. So far, I haven't gained any weight on it (fingers crossed)."

• Lis...
• Taken for less than 1 month
• August 27, 2021

"Love this medication!!! After trying everything for my depression/anxiety/BPD, I was starting to feel hopeless. Celexa was kind of working, but not as well as I had hoped. Tried every other mood stabilizer and antipsychotic out there. Finally, the doctor had me try Rexulti. I feel amazing. No longer feel hopeless, more motivated, and less moody. This medication doesn’t make you tired or upset your stomach like others do either! It’s great!"

• Man...
• October 2, 2017

"Bad. Feel restless and have anxiety attacks, also gaining weight. Have no energy and have to drink 3-4 cups of coffee every day just to stay awake and not crash my car driving to work. For me, not a good med. Tried Abilify, Seroquel, and Depakote in the past for anger and irritability, and those are as bad, if not worse, than the Rexulti. Been on 20 mg Lexapro for anxiety, depression, and autism spectrum disorder (ASD) for about 10 years, but it's not working very well anymore. Doctor suggested Latuda, going to try that next."

• Don...
• Taken for 5 to 10 years
• January 16, 2022

"Have been on Rexulti for 5 years. In the beginning, it was good. It made me feel more energetic, it wore off. Now I am bored with everything. I can’t work out like I did - for 45 years I worked out. It is either giving me muscle weakness or just too bored to do it, and you can’t get drunk if you wanted to. I thought it helped my ADD with thinking more clearly, it still helps with that. I hope it helps other people."

• Nou...
• Taken for 1 to 6 months
• July 30, 2021

"Hiya I went on this medication, I found in my particular experience was I put on lots off weight in a small amount of time. Which only added to my distress. I'm not saying this will happen to everyone, I'm just writing this review from my perspective."

• Ano...
• April 20, 2022

"Rexulti 3 mg worked very well for 1 year, but stopped working. I also gained 40 pounds with no change in diet or activity level. I’m still stuck with the weight even since I stopped it. So, eh. Take every review and side effect with a grain of salt. If you notice excessive weight gain in the beginning (my first 20 pounds was within 2 months or so), say something to your doctor. Don’t let them blow you off."

• Van...
• Taken for less than 1 month
• April 11, 2022

"Within a few days, I started having thoughts of self-harm (wrists) - completely unheard of for me + being interested in committing crimes/anti-social behaviour (once again, completely unheard of for me) & it upped my intrusive thoughts about faeces. I had to stop after 5 days. That was 2 days too long. I wanted to wait it out. I have a tendency/history of trying to be fair and waiting things out. This med or class of med isn't for me. I'm trying to get off Latuda by switching to something similar, as Latuda gives me panic/anxiety. For reference, I'm long-term on Pristiq 150mg/day for depression and intrusive thoughts + about 1/3 a year on 750mg Divalproex to be more positive about things & not so 'downer'. I'm a mid 30's middle class perfect-life on paper woman who can't work very much due to extreme fatigue & now recently medication mischief while my psychiatrist tries to find an antipsychotic med for my Bipolar type 2."

• Rea...
• September 20, 2022

"I am over 50 years old and have tried just about every antidepressant, antipsychotic, and mood stabilizer out there over the past 30 years. Rexulti salty is a lifesaver I have been on it for six months and I’ve never felt better. I can think I can function. There is a downside, weight gain. It came on pretty quickly and I gained over 10 pounds however the way it makes me feel is worth the weight. I’m on it without a typical antidepressant it seems to boost my Strattera which is not a prescribed as a standard antidepressant but is a SNRI. I’m also on Lamotrigine"

• Nic...
• May 10, 2021

"I want to preface this by saying that everybody's body chemistry is different and that one person's reaction to a medication will not necessarily be your reaction to the same med. With that being said, my experience with Rexulti was a horrible one. I have been on over 10 different antidepressants and anxiolytics, and this medication has caused the worst side effects I've ever experienced, namely, shortness of breath. During the second week, it got to the point where I couldn't get a full breath of air in, which led to severe anxiety and panic attacks. I went to an urgent care, where they said that my heart rate was so high that I needed to go to the ER. At the ER, I was given IV fluid and tested via an EKG, a chest X-ray, and a blood test. After everything came back fine, an ER doctor told me that it was likely an idiosyncratic reaction to the Rexulti in combination with heightened anxiety, and that the best course of action was to wait it out until the drug leaves my system. Good times."

• Isc...
• Taken for 1 to 6 months
• April 5, 2022

"Initially, it was a great drug. It acted, mostly, as an anxiolytic. At an initial dose of 0.5 mg, it made me calm, made my depression fade away. It even increased my energy, improved sleep, and libido. The problem, however, was the timing of the medication. I could not take it in the evening because it was making my sleep worse. In the morning, it made me sedated - but not too much; it was tolerable. After 2 months, my doctor bumped the dose to 1 mg - and that's where hell went loose. I slowly started developing side effects from it. The feeling of energy went away. Sedation increased to the point where I was unable to work. At the same time, it made my sleep much worse. Again, these side effects developed slowly - until, at some point, I realized that I felt really, really bad on Rexulti. Now I am trying to get off it before I get fired from my job."

• Min...
• Taken for less than 1 month
• January 20, 2023

"Ever since getting Covid, I have been having really bad existential and death OCD along with physical symptoms like a constant tension in my body. After trying a number of different meds, my psych prescribed this to help supplement my lexapro. It seems to be helping make my thoughts a little quieter and boosting my mood a bit. I'm still only on .25, and I may be switching to another SSRI soon, but right now, Rexulti seems to be helping somewhat. More than other drugs have."

• Anonymous
• Taken for less than 1 month
• October 18, 2017

"Added 1 mg to my Effexor 150 mg for depression and anxiety. This is helping, but I have major joint and body aches, with weight gain and stomach bloating. Also, OCD is worse. Don't know if I can stay on this due to these side effects."

• Alw...
• Taken for less than 1 month
• November 27, 2021

"Rexulti is the 6th AD that I had taken over 13 years. It's also the first one to work. Hands down, 10/10. The first 5 ADs provided minimal help and maximum side effects (fatigue, weight gain, insomnia, long-term IBS, etc.). In general, they moved serious depression and anxiety to moderate, but at an unsustainable cost. Rexulti is entirely different. Within 1 day, I noticed a big difference, in 3 days, I was me. For the first time in 13 years. My depression is in remission, my anxiety is around 20% of what it was. Huge win, and more to come. I think I need time for pathways and habits to rewire. Side effects: weight gain, but not a lot. Perhaps some sleep issues. Bonus: this is the time of year that I struggle the most. I had really bad Seasonal Affective Disorder, even as a kid. It's gone now, although the weight and sleep side effects may be SAD, not the drug."

• chr...
• Taken for less than 1 month
• February 29, 2024

"Game changer! I was misdiagnosed with bipolar disorder. This is my 2nd time going back on Rexulti and I feel so much better! I take 0.5 mg and I am more stable than I've ever been. I do feel sleepy at times, but I will just exercise to combat the sleepiness."

• Wen...
• May 1, 2021

"I went from a size 10 to a size 14 in three years of taking the medication. All symptoms of my major depression are gone, but obesity is setting in, and I may have to try something else for a while. I work out 3 times a week and watch what I eat."

• Nav...
• Taken for less than 1 month
• November 4, 2021

"I have been taking 40 mg of Prozac, but somehow it was not doing as good as it used to be for me. Plus, some fatigue, more stress, low motivation, and low mood. I always start medication with the lowest dose, so after checking with my doctor, who advised adding Rexulti 0.25 mg, initially, I had a headache that continued for 3 days, but slowly the medication got adjusted and I am now feeling much better, more energy, more motivation, and even libido is improving. So, folks, don’t lose hope and best of luck in your journey against this depression."

• Dai...
• Taken for 1 to 6 months
• August 18, 2021

"It’s been a month on Rexulti. I’ve been on so many things until I was diagnosed with BPD. I’m using these as a mood stabilizer, and I have never felt better. I’m concerned with the reviews of weight gain because I’m already a curvy lady, but if my brain is healthy, my body will follow suit. Highly recommend."

• vmr...
• Taken for less than 1 month
• February 24, 2018

"I have dealt with MDD, GAD, and PTSD meds for over 30 years and have had periods of relief with different cocktails, some lasting 5-6 years, but as many of you know, I built a tolerance to them all. A year and a half ago, my anxiety started waking me up and quickly became complete insomnia, and we tried many combinations for now four disorders and was able to sleep but woke feeling depressed. I take nefazodone, amitriptyline, and clonidine, and my psychiatrist gave me a Rexulti sample pack, but from the first 0.5 tablet, I had a hard time falling asleep and staying asleep until I had none. I rated Rexulti a 6 because in my experience with this product, adjunct to the tricyclics, my depression disappeared completely by the second, but for me, I choose sleep but am very envious of those people who have no bad side effects and good insurance because the cost of this on Medicare will put you in the donut hole."

• Que...
• Taken for 1 to 6 months
• May 16, 2024

"It has been a gradual incline in a positive direction for my life. I have been taking Rexulti for 3 months to treat my anxiety/depression and am currently taking 2.5 mg a day. I have felt boosted in social attributes such as charisma, being more personable, and a major decrease in apathy."

• rad...
• Taken for less than 1 month
• July 17, 2021

"I had high hopes because of the positive reviews, it helped for a little while. I wasn’t suicidal and I felt in control but soon my hands began to shake so much I couldn’t do my work and I’m so painfully tired all the time and constantly groggy like I just woke up. I feel more depressed on the meds than I did off. I slowly felt more and more numb until nothing felt good anymore. I don’t do anything other than work and sleep."

• bun...
• Taken for less than 1 month
• August 1, 2021

"This has been amazing and I am just starting my third free pack. I feel happy and content and hopeful for the first time in years. The change is amazing. I almost wondered if I was manic, as this new mood is so new. I'm able to handle stress. I'm able to enjoy tasks and work. I would absolutely recommend this to anyone. I haven't had the increased appetite that others have mentioned, but even if so, I would be overjoyed just due to the increase in mood and overall feeling of bliss."

• cha...
• Taken for 1 to 6 months
• February 16, 2024

"I've been taking it for a month. I'm diabetic and it has raised my sugar levels. My depression has had some relief but not totally. I've gained about 15 lbs since I started it, actually I was on Abilify first and recently switched over to Rexulti. I am sleepy before bedtime and wake up every 3 hours. I am willing to take anything in order to feel relief from depression."

• Gug...
• February 4, 2021

"I was on celexa 60mg for 20 years and it finally didn’t work anymore so my psychiatrist put me on abiilify first and then Rexulti which gave me uncontrollable body movements. Finally, I told my doctor to take me off all these medications and put me on a new drug which was lexapro 20mg and I feel fine. I strongly suggest not taking this drug unless you are severely depressed."

• jul...
• Taken for 1 to 6 months
• September 23, 2022

"I started rexulti after I started having severe panic attacks. Everything was going great and it made me feel unstoppable. I was going out with friends and trying to watch my weight considering a side effect was weight gain. Then the problems started happening. I started having severe depressive episodes, panic attacks that caused my chest to hurt, and crying meltdowns. I think that this medicine is great for many people. I just happen to be one of the ones that it doesn’t help."