Rexulti for Depression User Reviews (Page 2)

• Anonymous
• Taken for 1 to 6 months
• January 29, 2019

"I was put on .25 mg of rexulti to help the effect of my Lexapro. After increasing the rexulti to .50 I had my first major seizure. I was taken to the hospital and they said it was probably a non epileptic seizure. I called my doctor who said it could not be caused by the rexulti and increase the dosage to 1mg. After that my seizures increased to three or four times a week. I weaned myself off rexulti and now I am seizure free. Please be careful with this drug."

• npede
• Taken for 6 months to 1 year
• September 26, 2022

"I have bipolar and treatment-resistant depression. I had been on 8 different antidepressants and my psych added Abilify, which worked for the most part… but I developed akathisia so stopped. I was just on my Buspirone and Lamictal for about 5 months and I would dread getting up in the mornings, I’d just sit around and do nothing but stare at my phone, I was hardly taking care of my hygiene and hadn’t left the house in nearly three months. I finally told my psych what was going on and she added Rexulti and within two weeks my life changed. I wake up before my alarm, get up with no issues… I have nearly flipped our entire house (just finished our downstairs). My house is finally clean and liveable… I get out regularly and my marriage and relationship with my kids is a million times better. This is, in my own opinion, a miracle drug. It literally gave me my life back. I forgot who I really was until Rexulti."

• Not...
• January 10, 2020

"I was on this for Depressive Episode / Delusions. The side effects doctors won’t tell you about that happened to me: high blood sugar, high blood pressure, fast weight gain, lethargy, heart palpitations, constant panic attacks, insomnia, migraines, stomach and digestive issues, and much much more that ruined my entire summer. BTW: it only “works” for two weeks to a month then it stops completely as shown by literally half of the reviews on this. Disgusting. Put in more research before shoving in experimental antipsychotics into peoples mouths whenever they even feel a tad bit sad."

• Anonymous
• Taken for 1 to 6 months
• May 27, 2020

"I started on Rexulti at the low dose of 0.5 mg. It was really helping with my break through depression. I have been taking Wellbutrin for about 2 years and I needed a little boost. Well 2 months later and I gained 10 POUNDS. Super disappointed. The medication works, but be ready to be depressed about how much weight you've gained from it. Won't recommend."

• lrivera
• August 9, 2019

"This is my 3rd time trying Rexulti. Honestly, the first 2 times I took this medication my other psychiatrist only gave me 2mg. It did not work for me. But, I switched psychiatrist and they gave me 4mg for my depression. What a major difference. I am on weight watchers freestyle and I actually lost 3lbs on this medication while doing this program. Yes, it can cause weight gain. But, as soon as I started taking this medication I immediately went on weight watchers freestyle. The only thing is my sugar was high when I got blood work. You really need to watch your sugar when on this medication and eat a healthy diet. People say this medication causes weight gain so you have to be really careful and watch what you eat."

• squid...
• January 17, 2017

"Started and have stayed on the very lowest mg. of Rexulti.( for roughly four months) Almost immediately I felt so much better, and as the days went on, I felt "alive" again. Did have an issue with hot flashes, but it didn't last long. My Pdoc is trying to see if I can get a reduction on the cost of this med. Hope he can, because if not, I have no other med that works for me, and it's back to doomsville again. I have D.I.D., PTSD; anxiety, and panic disorder. This drug really keeps me focused, and on an even emotional keel. Very pleased."

• Geo...
• November 7, 2016

"I was prescribed Rexulti when my daily depression meds began to no longer work for me. It started working almost instantly I have been on Rexulti along with my daily meds, and I have been feeling better then ever."

• deelee
• Taken for 1 to 6 months
• December 15, 2022

"Effective as anything but at great cost. It quickly quieted my intrusive thoughts and gave me a boost of energy. But only 4 months later I've gained 35lbs on only 1mg of Rexulti. My BMI is over 25. My Dr says the sugar cravings and impulsive shopping are a good sign because it's dopamine-seeking activity. My mental health is better than it has been in years, and I'm going to be stopping this medication because of its detrimental effects to my weight, blood sugar, cholesterol, and self esteem. I don't even recognize my own body anymore. Not how it looks and not how it feels to move around in it. I almost wish I'd never experienced this because it feels like a tragedy to find something that works so well and not be able to keep taking it. It's, quite ironically, super depressing."

• LFR
• September 25, 2018

"I have had depression for years. I have ADHD also. I take wellbutrin, adderall and trazadone for it all. I have been on rexulti for a 3 weeks now. I have not gained any weight. I have lost 10lbs so far with WW on it. I am a full time college student. Rexulti has helped me more with of my ADHD symptoms. It has helped with my concentration also. I am glad they finally have come out with something that I am able to actually loose weight on."

• Jill...
• Taken for less than 1 month
• May 28, 2022

"I’ve read these reviews, like you, desperately hoping that I could find a medication that worked for me. I’m ultra sensitive to psych meds, am a slow metabolizer, and can’t take any SSRI’s or SNRI’s. I’ve had anxiety and depression for 23 years that started postpartum, and I am a 56 yo female. Rexulti, when added to my AD Nortriptyline, worked in 3 days to calm the agitated, panicky anxiety I was still struggling with. I take it in the morning, 0.5mg, and I don’t have any side effects. First time ever! I urge sensitive people to try this! God bless all of you that are struggling and trying!"

• Green...
• Taken for 1 to 6 months
• October 1, 2020

"I was taking Zoloft for depression and Rexulti was added to it. At first I felt great but after about 2 weeks I became very reckless. I didn’t care about anything. I didn’t care about Ccnsequences of my actions. I did lots of stupid stuff. I stopped taking it."

• Jhmedic
• Taken for 6 months to 1 year
• August 17, 2018

"I am one of those people who went through every antidepressant ever (paxil, prystiq, effexor, wellbutrin, etc.) Finally landed on prozac. Felt much better, but far from ok. After several months, rexulti was added. I am one of the lucky ones I suppose, because within hours I knew I had just won my own personal lottery - a med combo that worked for me. I now know what I have never known my whole life - what it's like to feel normal. I feel like this drug combo saved my life. My wife and kids do too best of luck to those struggling, because it took me 36 years to get the combination right. Tried it all. I recommend trying this combo to all. If it doesn't work, keep trying. It's worth the frustration when you feel it for the first time - normalcy. It is expensive unless you are willing to fill out the paperwork and get it for free. ;)"

• Cuteme
• Taken for 1 to 6 months
• August 30, 2018

"I think I have finally found what works for me! It took a lot of trial and error. I am currently on Pristiq (the generic kind) 100mg, Rexulti 1mg, and Vyvanse 75mg everyday. I take the Vyvanse and half an mg of Rexulti in the morning and Pristiq and another half an mg of Rexulti at night. The 1mg Rexulti all at once gave me anxiety by the end of the day. Now I have back my passion, my drive, and excitement for life! I have anxiety, depression, and ADD, but these medications balance out everything correctly."

• Bano
• Taken for 1 to 2 years
• May 2, 2019

"Rexulti works if you are in a rough spot, but I have gained 80 lbs using this. My brain works, but the weight gain is not healthy for me. My doctor and I have agreed to discontinue this medication and are looking into alternatives. I lost 15 pounds the first week I lowered my dosage in half. I will continue to reduce dosage until it is out of my system. Anyone that uses this I would recommend keeping tabs and seeing what effect it has on your body during the first few months."

• Rivera
• Taken for 1 to 6 months
• May 2, 2020

"I have been on rexulti 4mg with wellbutrinxl 300mg, zoloft 200mg and adderall 90mg a day. Rexulti is for my depression. Yes I have gained so weight but I feel better on 4mg of rexulti. I need to figure out how to loose weight with this drug. But I also have other thryoid issues that messes with my weight constantly. I would rather be happy and gain a little weight than be miserable. I have come to the conclusion the medications are what you make it. I feel lots of relief from my depression. For years I felt like, even with 2 antidepressants I need something to stabilize me more. This rexulti is the only medication that doesn't change my personality or change who I am as a person."

• LizziP
• June 29, 2017

"I have chronic depression (dysthymia) & anxiety, & the depression worsened recently despite being on Zoloft & Wellbutrin. My psychiatrist suggested we try Rexulti & wean me off the Wellbutrin. I started on 1mg, & I had a slight headache for the first two days. After that, I felt like I was doing a little better and my husband commented that I was more active than usual. My dose went up to 2mg a couple days ago. Now I feel like I can really tell a difference! I haven't felt depressed, I have more focus and creativity at work, & I've actually had enough motivation to do chores at home. I'm a little restless, which I'll keep an eye on, but I haven't noticed any other side effects besides that and the temporary headache. I'm optimistic!"

• WR2496
• Taken for less than 1 month
• August 17, 2017

"I've been trying different combinations of medicines for a good 6 years. I was put on Trintellex about a year ago, and that helped some, but my depression was still disabling. Recently, I went to my psychiatrist and asked for a change in medication. She decided to add rexulti as an add-on to my Trintellex. The result has been phenomenal. I feel better than I have in years. I have more energy, I'm less anxious, and I've been able to leave my house without feeling overhelmed at all. This medicine has is working VERY well for me."

• Pepper
• Taken for 6 months to 1 year
• February 20, 2020

"I was given Rexulti for add on for depression. At the time I was constantly in a dark place. Lots of thinking of death. Not suicidal. It helped overnight. However, I had some bad side effects. Tardive dyskinesia of the mouth. Although not in the way this condition is talked about. I was unable to chew. It was as if I lost that automatical chewing. I lost weight as I was unable to really eat anything except fluids. I was then put on yet another medication (can't recall the name.) This helped a little but did not help the way I had hoped. I decided to go off the Rexulti cold turkey. And I felt as though I was my body was failing me. Felt worse than the flu. I gave it 2 weeks before I had to start taking it again. Now I am slowly tapering to lower doses. Please listen when I say DO NOT go off cold turkey. I was on 3 mgs. I am now on 2mg and hope to change dose to 1mg next."

• Kells
• Taken for 2 to 5 years
• May 1, 2020

"Ok, so I've on on Rexulti for a few years now for depression. This is the best advise I can give someone thinking about taking this Medication. Currently I am on 2mg, I take it for major depression. My Dr started me off on 1mg. It seems like I had side efforts from the drug in the beginning. Dry mouth, weight gain, irritable and fatigue. So I started taking it at night. After about 2 weeks I then switched to morning again. Side efforts went away except for me eating :(. Overall its a good drug if it helps. I would recommend it. DOWNSIDE: do not just stop taking the drug! You most taper down on the medication. You will have effects if you just stop taking it. For example MOODY as heck. Then it takes a few days to build the medicine back up in your body for it to go away."

• No...
• Taken for less than 1 month
• June 5, 2016

"I have been on citalipram\celexa 40mg for years & it just wasn't working anymore....my Psych added the Rexulti .5 mg 3weeks ago and I have never felt better! I take them both @ bedtime. only real side affect is nausea sometimes in the middle of the night. I am so grateful to be able to live again. My doc has given me a month's more samples while they work to try and get my insurance to accept this new med....I hope they do cause my pharmacy quoted me $1000 (not a typo) for my prescription!"

• Melan...
• February 19, 2020

"I have been on Rexulti for approximately a month now, starting at the 0.5mg dose and now am titrating up to 1mg, I’m an 8 day cycle of alternating between the .5mg to 1mg respectively. This medication was prescribed to me as an add on to Persistent Depressive Disorder ( Dysthymia) by my psychiatrist. I am also prescribed Wellbutrin XL 300mg and Cipralex 20mg ... this cocktail seems to help me enough to get up for work and continue my duties in the home life as a husband and father without considering killing myself . Before I was given Rexulti I was semi suicidal daily so I guess it is helping . It is supposed to mood stabilize and give me an extra boost to get going however I do feel somewhat sedated while on this drug especially the days I take 1mg, which to me is not a bad think I would rather feel ok and sedated vs sad but energetic."

• Kat
• Taken for 1 to 6 months
• April 22, 2021

"I'm rating this a 10 because I've never had a med work so well on my bipolar depression and the effect was immediate! I can do things again with ease and not steady. I couldn't even get outta bed most days now I'm up early I shower and take care of myself, see friends, do hobbies like painting writing and exercising. I laugh again and it felt like a light switch turned on in my brain. Very thankful for this medication. I take along with lamictal."

• rexul...
• May 5, 2016

"in my third week of 05 mg as add on to Paxil, After first week I thought to myself, "so this is what its like to feel good, up beat and happy" Now this week i definately notice increase in appetite, constantly snacking and looking for something to eat. That will not make me happy as weight issues were already a problem. Also a bit troublesome is I am feeling tingling in my arm. from wrist all the way up to my elbow. Tingling numb, soemthing is off. My guess its the rexulti. See doctor on MOnday and will update. If it gets worse I will follow up sooner"

• Bearsky
• Taken for less than 1 month
• August 23, 2016

"I'm currently on Day 8 of the Rexulti trial pack (stepping up dosage) and so far so good...except that I feel that it's deadened sex drive. However, that can be remedied I think. The benefit is that my "painful emotions" accompanying serious depression have all but vanished. And so far I have not experienced any akathisia, which is my most feared side effect from any of the atypical antipsychotics (such as Seroquel). We'll see how it continues. Yes, it is quite expensive, but I think MediCal will cover."

• kirt
• August 24, 2017

"I take Effexor 150mg for my depression & anxiety but if you know effexor its really only for anxiety, so we tried Effexor WITH Rexulti. Rexulti really takes care of depression where effexor doesn't. I started on .5mg for two weeks and then went up to 1 mg for three weeks, which I'm at now, and then I'm going up to 2mg in the next few days. It really helps with depression. I'm always on my feet, all day, always doing something, and I don't even care. It's not a big deal, even. I just do things. It's so cool, I've been apathetic my whole life, and now it's changed. There are side effects, I get headaches and every time I go up a dose, I have huge mood swings for a few days while my body adjusts. But thats okay. Awesome medication."