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Acetaminophen / diphenhydramine and Sleepy: What Users Say

Brand names: Tylenol PM, Headache Relief PM, Pain Reliever PM, Midol PM, Percogesic Extra Strength, Headache Formula PM, Legatrin PM, Bayer Select Max Strength Night Time Pain, ConRx PM, Acetadryl, Night Time Pain, Percogesic Original Strength, Unisom PM Pain, Genapap PM, Mapap PM, Counteract PM Extra Strength, Wal-Nadol PM Extra Strength, Excedrin PM, Tylenol Sore Throat Nighttime, Pharbetol PM, Non-Aspirin PM Extra Strength Acetaminophen PM Extra Strength Robitussin Honey Severe Cough, Flu + Sore Throat CF Max Nighttime Anacin PM Aspirin Free …show all brand names

Sleepy: mentioned by 3 users (4.3%)

Based on user experiences from 69 Acetaminophen / diphenhydramine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

drowsiness 13.0%
anxiety 7.2%
dry mouth 4.3%
headaches 4.3%
insomnia 4.3%
sleepy 4.3%

Reviews for Acetaminophen / diphenhydramine

Commonly mentioned side effects
  • Sha...
  • February 10, 2015

For Pain "I was very surprised when I took this medicine. I took it at 9 PM, and by 9:30, I was in bed sleeping. It's a high-power pill, and I rested all night. It's a good pill besides the fact that I woke up the next morning and barely could get up and get dressed for work because I was still sleepy from the pill. It finally wore off at about 10 AM. It helped me a lot. I was told by a friend to take it for pain, and I'm glad I got it."

9 / 10
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40 Report
  • Ang...
  • Taken for less than 1 month
  • September 8, 2019

For Pain "I have taken this medication for pain in my foot due to gout. Nothing else I bought over the counter worked. I read the bottle and decided to try it. It eased my pain more than I ever thought an over-the-counter medicine could. The only thing to be aware of is it makes you sleepy and drowsy. But it works!"

10 / 10
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3 Report
  • Anonymous
  • February 20, 2010

For Pain "The best for back pain, cramps. It does make you sleepy, so don't drive. Helps you sleep when you're in pain. I have been taking it for years. LOVE IT!"

10 / 10
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23 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.