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Medications for Motion Sickness

Other names: Sea Sickness

A disturbance of the inner ear that is caused by repeated motion

Drugs used to treat Motion Sickness

The medications listed below are related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
meclizine 8.4 53 reviews for meclizine to treat Motion Sickness Rx/OTC B N X
Generic name:
meclizine systemic
Brand names:
Bonine, Antivert, Dramamine Less Drowsy, Travel Sickness, Dramamine II, Travel-Ease
Drug class:
anticholinergic antiemetics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Dramamine 9.0 28 reviews for Dramamine to treat Motion Sickness OTC B N X
Generic name:
dimenhydrinate systemic
Drug class:
anticholinergic antiemetics
For consumers:
dosage, interactions, side effects
scopolamine 6.2 143 reviews for scopolamine to treat Motion Sickness Rx C N X
Generic name:
scopolamine systemic
Brand name:
Transderm-Scop
Drug class:
anticholinergics/antispasmodics, anticholinergic antiemetics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
promethazine 7.3 10 reviews for promethazine to treat Motion Sickness Rx C N X
Generic name:
promethazine systemic
Brand names:
Antinaus 50, Phenadoz, Promethegan
Drug class:
antihistamines, phenothiazine antiemetics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Bonine 8.5 34 reviews for Bonine to treat Motion Sickness Rx/OTC B N X
Generic name:
meclizine systemic
Drug class:
anticholinergic antiemetics
For consumers:
dosage, interactions, side effects
Antivert Rate Add review Rx/OTC B N X
Generic name:
meclizine systemic
Drug class:
anticholinergic antiemetics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
dimenhydrinate 8.9 35 reviews for dimenhydrinate to treat Motion Sickness Rx/OTC B N X
Generic name:
dimenhydrinate systemic
Brand names:
Dramamine, Dramamine for Kids, Driminate, Travel-Eze, Triptone
Drug class:
anticholinergic antiemetics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Dramamine Less Drowsy 10 1 review for Dramamine Less Drowsy to treat Motion Sickness Rx/OTC B N X
Generic name:
meclizine systemic
Drug class:
anticholinergic antiemetics
For consumers:
dosage, interactions, side effects
Transderm-Scop 6.8 67 reviews for Transderm-Scop to treat Motion Sickness Rx C N X
Generic name:
scopolamine systemic
Drug class:
anticholinergics/antispasmodics, anticholinergic antiemetics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Benadryl Rate Add review Rx/OTC B N X
Generic name:
diphenhydramine systemic
Drug class:
miscellaneous anxiolytics, sedatives and hypnotics, antihistamines, anticholinergic antiemetics, anticholinergic antiparkinson agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
diphenhydramine 9.0 3 reviews for diphenhydramine to treat Motion Sickness Rx/OTC B N X
Generic name:
diphenhydramine systemic
Brand names:
Benadryl, Banophen, Benadryl Allergy, Allermax, Benadryl Children's Allergy, Dicopanol, Diphedryl, Diphen, Complete Allergy Relief, Diphenhist, Dormin, Dytuss, Siladryl Allergy, Silphen Cough, Twilite, Valu-Dryl
Drug class:
miscellaneous anxiolytics, sedatives and hypnotics, antihistamines, anticholinergic antiemetics, anticholinergic antiparkinson agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Travel Sickness Rate Add review Rx/OTC B N X
Generic name:
meclizine systemic
Drug class:
anticholinergic antiemetics
For consumers:
dosage, interactions, side effects
Banophen Rate Add review Rx/OTC B N X
Generic name:
diphenhydramine systemic
Drug class:
miscellaneous anxiolytics, sedatives and hypnotics, antihistamines, anticholinergic antiemetics, anticholinergic antiparkinson agents
For consumers:
dosage, interactions, side effects
Benadryl Allergy 9.0 1 review for Benadryl Allergy to treat Motion Sickness Rx/OTC B N X
Generic name:
diphenhydramine systemic
Drug class:
miscellaneous anxiolytics, sedatives and hypnotics, antihistamines, anticholinergic antiemetics, anticholinergic antiparkinson agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Dramamine II Rate Add review Rx/OTC B N X
Generic name:
meclizine systemic
Drug class:
anticholinergic antiemetics
For consumers:
dosage, interactions, side effects
Travel-Ease Rate Add review Rx/OTC B N X
Generic name:
meclizine systemic
Drug class:
anticholinergic antiemetics
For consumers:
dosage, interactions, side effects
Allermax Rate Add review Rx/OTC B N X
Generic name:
diphenhydramine systemic
Drug class:
miscellaneous anxiolytics, sedatives and hypnotics, antihistamines, anticholinergic antiemetics, anticholinergic antiparkinson agents
For consumers:
dosage, interactions, side effects
Antinaus 50 Rate Add review Rx C N X
Generic name:
promethazine systemic
Drug class:
antihistamines, phenothiazine antiemetics
For consumers:
dosage, interactions, side effects
Benadryl Children's Allergy Rate Add review Rx/OTC B N X
Generic name:
diphenhydramine systemic
Drug class:
miscellaneous anxiolytics, sedatives and hypnotics, antihistamines, anticholinergic antiemetics, anticholinergic antiparkinson agents
For consumers:
dosage, interactions, side effects
Dicopanol Rate Add review Rx/OTC B N X
Generic name:
diphenhydramine systemic
Drug class:
miscellaneous anxiolytics, sedatives and hypnotics, antihistamines, anticholinergic antiemetics, anticholinergic antiparkinson agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Diphedryl Rate Add review Rx/OTC B N X
Generic name:
diphenhydramine systemic
Drug class:
miscellaneous anxiolytics, sedatives and hypnotics, antihistamines, anticholinergic antiemetics, anticholinergic antiparkinson agents
For consumers:
dosage, interactions, side effects
Diphen Rate Add review Rx/OTC B N X
Generic name:
diphenhydramine systemic
Drug class:
miscellaneous anxiolytics, sedatives and hypnotics, antihistamines, anticholinergic antiemetics, anticholinergic antiparkinson agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Phenadoz Rate Add review Rx C N X
Generic name:
promethazine systemic
Drug class:
antihistamines, phenothiazine antiemetics
For consumers:
dosage, interactions, side effects
Promethegan Rate Add review Rx C N X
Generic name:
promethazine systemic
Drug class:
antihistamines, phenothiazine antiemetics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Complete Allergy Relief Rate Add review Rx/OTC B N X
Generic name:
diphenhydramine systemic
Drug class:
miscellaneous anxiolytics, sedatives and hypnotics, antihistamines, anticholinergic antiemetics, anticholinergic antiparkinson agents
For consumers:
dosage, interactions, side effects

Frequently asked questions

View more FAQ

Alternative treatments for Motion Sickness

The following products are considered to be alternative treatments or natural remedies for Motion Sickness. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However, there may be historical, cultural or anecdotal evidence linking their use to the treatment of Motion Sickness.

Learn more about Motion Sickness

Care guides

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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