Diphenhist Interactions
There are 450 drugs known to interact with Diphenhist (diphenhydramine), along with 8 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 14 are major, 434 are moderate, and 2 are minor.
- View all 450 medications that may interact with Diphenhist
- View Diphenhist alcohol/food interactions (1)
- View Diphenhist disease interactions (8)
Most frequently checked interactions
View interaction reports for Diphenhist (diphenhydramine) and the medicines listed below.
- acetaminophen
- acyclovir
- albuterol
- alprazolam
- amitriptyline
- Artificial Tears (ocular lubricant ophthalmic)
- aspirin
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flonase (fluticasone nasal)
- fluticasone nasal
- furosemide
- gabapentin
- ibuprofen
- lisinopril
- lorazepam
- magnesium oxide
- melatonin
- metformin
- omeprazole
- oxygen
- potassium chloride
- prednisone
- ranitidine
- sertraline
- topiramate
- trazodone
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Zinc (zinc sulfate)
Diphenhist alcohol/food interactions
There is 1 alcohol/food interaction with Diphenhist (diphenhydramine).
Diphenhist disease interactions
There are 8 disease interactions with Diphenhist (diphenhydramine) which include:
- depression
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
Report options
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More about Diphenhist (diphenhydramine)
- Diphenhist consumer information
- Compare alternatives
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- Drug images
- Latest FDA alerts (2)
- Side effects
- Dosage information
- During pregnancy
- Drug class: anticholinergic antiemetics
- Breastfeeding
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
