Comparing Protonix vs Zantac
| Protonix (pantoprazole) | Zantac (ranitidine) |
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| Protonix (pantoprazole) | Zantac (ranitidine) |
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Prescription only
Protonix is used to treat erosive esophagitis associated with gastroesophageal reflux disease (GERD), hypersecretory conditions including Zollinger-Ellison (ZE) syndrome, and for the maintenance of... View more |
Prescription and OTC
Zantac was an acid-suppressing agent that was used to treat a wide range of gastric-acid-related disorders, including gastric ulcers, heartburn, and GERD. Headaches were the most common side effect... View more |
Related suggestions Stomach Ulcer
Erosive Esophagitis
Duodenal Ulcer
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| More about Protonix (pantoprazole) | More about Zantac (ranitidine) | ||||||||
| Ratings & Reviews | |||||||||
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Protonix has an average rating of 7.2 out of 10 from a total of 83 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 22% reported a negative effect. |
Zantac has an average rating of 7.5 out of 10 from a total of 83 ratings on Drugs.com. 71% of reviewers reported a positive effect, while 20% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Protonix side effects |
View all Zantac side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||
View all Protonix prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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| Brand Names | |||||||||
| Other pantoprazole brands include: Protonix IV | Other ranitidine brands include: Acid Control 150, Acid Control 75, Acid Reducer, Acid Reducer Non-Prescription Strength, Acid Relief, Berkley and Jensen Acid Reducer Maximum Strength, Careone Acid Reducer, Deprizine, Equaline Heartburn Relief, Sunmark Acid Reducer Maximum Strength View more | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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1 hour |
2.5 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 181 drugs are known to interact with Protonix:
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A total of 149 drugs are known to interact with Zantac:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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February 02, 2000 |
June 09, 1983 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.