Omeprazole Alternatives Compared
| Omeprazole | Pantoprazole | Nexium (esomeprazole) |
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| Omeprazole | Pantoprazole | Nexium (esomeprazole) |
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Prescription and OTC
Omeprazole decreases stomach acid production which promotes the healing of gastric and duodenal ulcers and other inflamed areas of gastrointestinal tissue. The risk of interactions with omeprazole... View more |
Prescription only
Pantoprazole is a proton pump inhibitor that decreases acid secretion in the stomach and may be given to relieve the symptoms of heartburn or to allow inflamed tissue in the gastrointestinal tract to... View more |
Prescription only
Nexium effectively heals inflamed tissue in the gastrointestinal tract and relieves symptoms of heartburn. Nexium is available orally and as an IV preparation that may be used in adults and children... View more |
Related suggestions Helicobacter Pylori Infection
Erosive Esophagitis
Barrett's Esophagus
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| More about Omeprazole | More about Pantoprazole | More about Nexium (esomeprazole) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Omeprazole has an average rating of 4.6 out of 10 from a total of 491 ratings on Drugs.com. 32% of reviewers reported a positive effect, while 53% reported a negative effect. |
Pantoprazole has an average rating of 5.0 out of 10 from a total of 431 ratings on Drugs.com. 37% of reviewers reported a positive effect, while 47% reported a negative effect. |
Nexium has an average rating of 6.1 out of 10 from a total of 210 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 35% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Omeprazole prices |
View all Pantoprazole prices |
View all Nexium prices |
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| Dosage Forms Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Omesec, Prilosec, Prilosec OTC | Protonix, Protonix IV | Other esomeprazole brands include: Nexium 24HR, Nexium IV | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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1.5 hours |
1 hour |
1.5 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 225 drugs are known to interact with Omeprazole:
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A total of 167 drugs are known to interact with Pantoprazole:
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A total of 200 drugs are known to interact with Nexium:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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June 20, 2003 |
February 02, 2000 |
N/A |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient resources | ||||||||||||||||||||||||||
| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.