Comparing Nexium vs Prilosec OTC
| Nexium (esomeprazole) | Prilosec OTC (omeprazole) |
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| Nexium (esomeprazole) | Prilosec OTC (omeprazole) |
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Prescription only
Nexium is an acid-suppressing agent used to treat conditions associated with excessive stomach acid production, such as gastroesophageal reflux (GERD) and stomach ulcers. Nexium is available orally... View more |
Over-the-counter
Prescribed for GERD, Indigestion. Prilosec OTC may also be used for purposes not listed in this medication guide. |
Related suggestions |
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| More about Nexium (esomeprazole) | More about Prilosec OTC (omeprazole) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Nexium has an average rating of 6.2 out of 10 from a total of 211 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 33% reported a negative effect. |
Prilosec OTC has an average rating of 8.7 out of 10 from a total of 21 ratings on Drugs.com. 81% of reviewers reported a positive effect, while 0% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Nexium side effects |
View all Prilosec OTC side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Nexium prices |
View all Prilosec OTC prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other esomeprazole brands include: Nexium 24HR, Nexium IV | Other omeprazole brands include: Omesec, Prilosec | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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1.5 hours |
1.5 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 214 drugs are known to interact with Nexium:
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A total of 240 drugs are known to interact with Prilosec OTC:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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N/A |
June 20, 2003 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.