Comparing Methylprednisolone vs Plaquenil
| Methylprednisolone | Plaquenil (hydroxychloroquine) |
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| Methylprednisolone | Plaquenil (hydroxychloroquine) |
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Prescription only
Methylprednisolone effectively controls inflammation and an overactive immune system but may not be suitable for everybody. Long-term use is limited by potentially severe side effects such as... View more |
Prescription only
Prescribed for Rheumatoid Arthritis, Lupus, Lyme Disease - Arthritis, Dermatomyositis, Malaria, Malaria Prevention. Plaquenil may also be used for purposes not listed in this medication guide. |
Related suggestions |
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| More about Methylprednisolone | More about Plaquenil (hydroxychloroquine) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Methylprednisolone has an average rating of 7.1 out of 10 from a total of 485 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 24% reported a negative effect. |
Plaquenil has an average rating of 6.4 out of 10 from a total of 158 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 28% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Methylprednisolone side effects |
View all Plaquenil side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Methylprednisolone prices |
View all Plaquenil prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Depo-Medrol, Medrol, Medrol Dosepak, MethylPREDNISolone Dose Pack, Solu-Medrol | Other hydroxychloroquine brands include: Sovuna | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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3.5 hours |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
Excluding First Trimester
Category D
Positive evidence of risk
First Trimester See the full pregnancy warnings document. |
Category N
Not classified
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 623 drugs are known to interact with Methylprednisolone:
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A total of 582 drugs are known to interact with Plaquenil:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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October 24, 1957 |
April 18, 1955 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
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| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.