Comparing Methylprednisolone vs Prednisone
| Methylprednisolone | Prednisone |
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| Methylprednisolone | Prednisone |
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Prescription only
Methylprednisolone effectively controls inflammation and an overactive immune system but may not be suitable for everybody. Long-term use is limited by potentially severe side effects such as... View more |
Prescription only
Prednisone effectively controls inflammation and an overactive immune system but may not be suitable for everybody. Long-term use is limited by potentially severe side effects such as adrenal... View more |
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| More about Methylprednisolone | More about Prednisone | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Methylprednisolone has an average rating of 7.1 out of 10 from a total of 485 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 24% reported a negative effect. |
Prednisone has an average rating of 7.5 out of 10 from a total of 867 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 18% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Methylprednisolone side effects |
View all Prednisone side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Methylprednisolone prices |
View all Prednisone prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Depo-Medrol, Medrol, Medrol Dosepak, MethylPREDNISolone Dose Pack, Solu-Medrol | Rayos | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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3.5 hours |
4 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
Excluding First Trimester
Category D
Positive evidence of risk
First Trimester See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
Excluding First Trimester
Category D
Positive evidence of risk
First Trimester See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 623 drugs are known to interact with Methylprednisolone:
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A total of 622 drugs are known to interact with Prednisone:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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October 24, 1957 |
February 21, 1955 |
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| WADA Class View classifications | |||||||||||||||||
| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.