Comparing Dexamethasone vs Methylprednisolone
| Dexamethasone | Methylprednisolone |
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| Dexamethasone | Methylprednisolone |
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Prescription only
Dexamethasone reduces inflammation and calms down an overactive immune system and is significantly more potent than prednisolone. It may be given to control inflammation associated with eye disease... View more |
Prescription only
Methylprednisolone effectively controls inflammation and an overactive immune system but may not be suitable for everybody. Long-term use is limited by potentially severe side effects such as... View more |
Related suggestions Rheumatoid Arthritis
Allergic Rhinitis
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| More about Dexamethasone | More about Methylprednisolone | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Dexamethasone has an average rating of 5.9 out of 10 from a total of 162 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 36% reported a negative effect. |
Methylprednisolone has an average rating of 7.1 out of 10 from a total of 485 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 24% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Dexamethasone side effects |
View all Methylprednisolone side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Dexamethasone prices |
View all Methylprednisolone prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| De-Sone LA, Dexabliss, Dexamethasone Intensol, Dxevo, Hemady, HiDex, TaperDex, Zcort, ZoDex View more | Depo-Medrol, Medrol, Medrol Dosepak, MethylPREDNISolone Dose Pack, Solu-Medrol | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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N/A |
3.5 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
Excluding First Trimester
Category D
Positive evidence of risk
First Trimester See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 807 drugs are known to interact with Dexamethasone:
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A total of 623 drugs are known to interact with Methylprednisolone:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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October 30, 1958 |
October 24, 1957 |
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| WADA Class View classifications | |||||||||||||||||
| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.