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Medications for Atopic Dermatitis

Other names: Allergic Dermatitis; Contact Dermatitis; Dermatitis, Allergic; Dermatitis, Contact

Atopic dermatitis is a skin condition characterized by a recurring rash associated with itch. Most people with atopic dermatitis have at least one of the following other conditions: hay fever, asthma, chronic urticaria, or food allergies.

Dermatitis is another name for skin inflammation and the word “eczema” may be used interchangeably with dermatitis; therefore, atopic dermatitis is the same as atopic eczema.

Atopic dermatitis is common among certain families and it usually starts in early childhood, although it can occur at any age. It is the most common form of eczema seen in children. The exact cause of atopic dermatitis is not known, but researchers believe it may involve genetics, a defect in the skin’s barrier, the environment, and/or the immune system.

What are the Symptoms of Atopic Dermatitis?

  • Red, inflamed areas of skin that are very itchy.
  • Atopic dermatitis may affect the face (especially in infants), hands, feet or in the creases and folds of the skin on the arms and legs.
  • Affected areas may take on a scaly appearance.
  • General dry skin all over the body is also common.
  • Constant scratching may lead to thickened areas of skin or broken areas of skin which are prone to infection and may become crusted and “weepy”.

Symptoms of atopic dermatitis usually come and go. Periods of activity are called “flares” and these are usually followed by periods of relative skin normality.

If atopic dermatitis developed in childhood, it often improves with age, although some people may experience flares now and then in adulthood.

How is Atopic Dermatitis Treated?

Having a good skincare routine every day helps in the management of atopic dermatitis.

Skin should be cleansed with a mild, soap-free cleanser that is recommended for people prone to dermatitis. Using a cleanser that is too harsh can aggravate dermatitis. Cleansing should be followed by a hypoallergenic moisturizer – again choose one recommended for atopic dermatitis.

Try to pinpoint any atopic dermatitis triggers. These are events or substances that make your dermatitis worse and may include chemical irritants, stress, hot/cold temperatures, sweating, pollen, animal dander, dust, or hormones. Try and minimize exposure to these if possible.

Use your OTC and prescription medications exactly as your doctor has prescribed. These are important to help control flares or keep them at bay.

Dress in soft breathable fabrics and avoid itchy fabrics like wool.

Drugs used to treat Atopic Dermatitis

The medications listed below are related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
triamcinolone 8.7 17 reviews for triamcinolone to treat Atopic Dermatitis Rx C N
Generic name:
triamcinolone topical
Brand names:
Kenalog, Aristocort A, Triderm, Cinolar, DermacinRx Trizapak, Juulissa Pharmapak, Trianex, Triasil, Tritocin
Drug class:
topical steroids
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Dupixent 7.0 111 reviews for Dupixent to treat Atopic Dermatitis Rx N
Generic name:
dupilumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
clobetasol 9.7 14 reviews for clobetasol to treat Atopic Dermatitis Rx C N
Generic name:
clobetasol topical
Brand names:
Clobex, Temovate, Clobevate, Clodan, Cormax, Cormax Scalp, Embeline, Embeline E, Impeklo, Olux, Olux-E, Tovet
Drug class:
topical steroids
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Eucrisa 5.8 276 reviews for Eucrisa to treat Atopic Dermatitis Rx N
Generic name:
crisaborole topical
Drug class:
miscellaneous topical agents
For consumers:
dosage, side effects
For professionals:
Prescribing Information
Rinvoq 7.7 35 reviews for Rinvoq to treat Atopic Dermatitis Rx N
Generic name:
upadacitinib systemic
Drug class:
antirheumatics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Opzelura 9.5 4 reviews for Opzelura to treat Atopic Dermatitis Rx N
Generic name:
ruxolitinib topical
Drug class:
topical antineoplastics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
dupilumab 7.0 116 reviews for dupilumab to treat Atopic Dermatitis Rx N
Generic name:
dupilumab systemic
Brand name:
Dupixent
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Adbry 5.5 6 reviews for Adbry to treat Atopic Dermatitis Rx N
Generic name:
tralokinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
betamethasone 7.7 16 reviews for betamethasone to treat Atopic Dermatitis Rx C N
Generic name:
betamethasone topical
Brand names:
Diprolene, Diprolene AF, Luxiq, Beta-Val
Drug class:
topical steroids
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Cibinqo 8.6 5 reviews for Cibinqo to treat Atopic Dermatitis Rx N
Generic name:
abrocitinib systemic
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
tacrolimus 6.5 122 reviews for tacrolimus to treat Atopic Dermatitis Rx C N
Generic name:
tacrolimus topical
Brand name:
Protopic
Drug class:
miscellaneous topical agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
crisaborole 5.8 283 reviews for crisaborole to treat Atopic Dermatitis Rx N
Generic name:
crisaborole topical
Brand name:
Eucrisa
Drug class:
miscellaneous topical agents
For consumers:
dosage, side effects
For professionals:
AHFS DI Monograph
Protopic 6.9 75 reviews for Protopic to treat Atopic Dermatitis Rx C N
Generic name:
tacrolimus topical
Drug class:
miscellaneous topical agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
tralokinumab 6.1 7 reviews for tralokinumab to treat Atopic Dermatitis Rx N
Generic name:
tralokinumab systemic
Brand name:
Adbry
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
upadacitinib 7.8 36 reviews for upadacitinib to treat Atopic Dermatitis Rx N
Generic name:
upadacitinib systemic
Brand name:
Rinvoq
Drug class:
antirheumatics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
abrocitinib 8.6 5 reviews for abrocitinib to treat Atopic Dermatitis Rx N
Generic name:
abrocitinib systemic
Brand name:
Cibinqo
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Ebglyss 10 2 reviews for Ebglyss to treat Atopic Dermatitis Rx N
Generic name:
lebrikizumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ruxolitinib 9.5 4 reviews for ruxolitinib to treat Atopic Dermatitis Rx N
Generic name:
ruxolitinib topical
Brand name:
Opzelura
Drug class:
topical antineoplastics
For consumers:
interactions, side effects
For professionals:
AHFS DI Monograph
tapinarof 10 1 review for tapinarof to treat Atopic Dermatitis Rx N
Generic name:
tapinarof topical
Brand name:
Vtama
Drug class:
topical antipsoriatics
For consumers:
dosage, side effects
For professionals:
AHFS DI Monograph
Vtama 10 1 review for Vtama to treat Atopic Dermatitis Rx N
Generic name:
tapinarof topical
Drug class:
topical antipsoriatics
For consumers:
dosage, side effects
For professionals:
Prescribing Information
fluocinonide 6.4 5 reviews for fluocinonide to treat Atopic Dermatitis Rx C N
Generic name:
fluocinonide topical
Brand name:
Vanos
Drug class:
topical steroids
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
hydrocortisone 5.0 3 reviews for hydrocortisone to treat Atopic Dermatitis Rx/OTC C N
Generic name:
hydrocortisone topical
Brand names:
Cortizone-10, Locoid Lipocream, Ala-Cort, Ala-Scalp, Ala-Scalp HP, Aquanil HC, Aquax-H, Beta HC, Caldecort, Cortizone-5, Dermtex HC, Hydroxate Gel, Hydroxym Cream, Hydroxym Gel, Itch-X Lotion, Locoid, NuCort, Pandel, Sarnol-HC, Texacort, U-Cort
Drug class:
topical steroids
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
prednisone 3.0 3 reviews for prednisone to treat Atopic Dermatitis Rx C N
Generic name:
prednisone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
mometasone 8.8 8 reviews for mometasone to treat Atopic Dermatitis Rx C N
Generic name:
mometasone topical
Brand name:
Elocon
Drug class:
topical steroids
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Elidel 6.3 22 reviews for Elidel to treat Atopic Dermatitis Rx C N
Generic name:
pimecrolimus topical
Drug class:
miscellaneous topical agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information

Frequently asked questions

View more FAQ

Alternative treatments for Atopic Dermatitis

The following products are considered to be alternative treatments or natural remedies for Atopic Dermatitis. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However, there may be historical, cultural or anecdotal evidence linking their use to the treatment of Atopic Dermatitis.

Learn more about Atopic Dermatitis

Care guides

Symptoms and treatments

Medicine.com guides (external)

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.