Comparing Dexamethasone vs Hydrocortisone
| Dexamethasone | Hydrocortisone |
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| Dexamethasone | Hydrocortisone |
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Prescription only
Dexamethasone reduces inflammation and calms down an overactive immune system and is significantly more potent than prednisolone. It may be given to control inflammation associated with eye disease... View more |
Prescription only
Prescribed for Adrenocortical Insufficiency, Addison's Disease, Asthma - acute, Crohn's Disease - Active, Ulcerative Proctitis, Inflammatory Bowel Disease, Inflammatory Conditions, Shock, Ulcerative... View more |
Related suggestions Inflammatory Conditions
Ulcerative Colitis
Asthma, acute
Inflammatory Bowel Disease
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| More about Dexamethasone | More about Hydrocortisone | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Dexamethasone has an average rating of 5.9 out of 10 from a total of 162 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 36% reported a negative effect. |
Hydrocortisone has an average rating of 7.5 out of 10 from a total of 31 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 10% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Dexamethasone side effects |
View all Hydrocortisone side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Dexamethasone prices |
View all Hydrocortisone prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| De-Sone LA, Dexabliss, Dexamethasone Intensol, Dxevo, Hemady, HiDex, TaperDex, Zcort, ZoDex View more | Alkindi Sprinkle, Cortef, Cortenema, Cortifoam, Solu-Cortef | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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N/A |
12 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 807 drugs are known to interact with Dexamethasone:
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A total of 637 drugs are known to interact with Hydrocortisone:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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October 30, 1958 |
December 21, 1951 |
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| WADA Class View classifications | |||||||||||||||||
| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.