Comparing Methadone vs Tramadol
Methadone | Tramadol |
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Methadone | Tramadol |
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Prescription only
Methadone is a potent opioid analgesic that may be used to relieve severe pain unresponsive to other strong pain relievers; however, it is more commonly used to treat opioid addiction. There is a... View more |
Prescription only
Tramadol is a strong opioid pain relieving medication that may be used to treat moderate to severe general and nerve-related pain. Tramadol may be habit-forming and misuse can cause addiction... View more |
Related suggestions Chronic Pain
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More about Methadone | More about Tramadol | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Methadone has an average rating of 8.7 out of 10 from a total of 598 ratings on Drugs.com. 85% of reviewers reported a positive effect, while 5% reported a negative effect. |
Tramadol has an average rating of 7.0 out of 10 from a total of 1856 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 24% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: methadone side effects in more detail. |
See also: tramadol side effects in more detail. |
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Generic Availability | |||||||||||||||||
Lower cost generic |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all methadone prices |
View all tramadol prices |
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Dosage Forms Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Methadone Diskets, Methadose, Methadose Sugar-Free | ConZip, Qdolo, Tramadol Hydrochloride ER | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
30 hours |
5.2 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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Pregnancy Category | |||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 725 drugs are known to interact with methadone:
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A total of 668 drugs are known to interact with tramadol:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
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First Approval Date | |||||||||||||||||
August 13, 1947 |
March 03, 1995 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.