Comparing Acetaminophen / Oxycodone vs Methadone
| Acetaminophen / oxycodone | Methadone |
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| Acetaminophen / oxycodone | Methadone |
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Prescription only
Acetaminophen/oxycodone may be used to relieve moderate-to-severe pain that is unrelieved by nonopioid analgesics; however, its use is limited by the dependence and addiction potential of the... View more |
Prescription only
Methadone is a potent opioid analgesic that may be used to relieve severe pain unresponsive to other strong pain relievers; however, it is more commonly used to treat opioid addiction. There is a... View more |
Related suggestions |
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| More about Acetaminophen / oxycodone | More about Methadone | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Acetaminophen / oxycodone has an average rating of 6.8 out of 10 from a total of 878 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 27% reported a negative effect. |
Methadone has an average rating of 8.7 out of 10 from a total of 607 ratings on Drugs.com. 84% of reviewers reported a positive effect, while 6% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Methadone side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Acetaminophen / oxycodone prices |
View all Methadone prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Nalocet, Oxycet, Percocet, Percocet 10/325, Percocet 10/650, Percocet 2.5/325, Percocet 5/325, Percocet 7.5/325, Percocet 7.5/500, Primlev, Prolate, Xolox View more | Methadone Diskets, Methadose, Methadose Sugar-Free | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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7.9 hours |
30 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 691 drugs are known to interact with Acetaminophen / oxycodone:
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A total of 839 drugs are known to interact with Methadone:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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August 31, 1976 |
August 13, 1947 |
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| WADA Class View classifications | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Naproxen
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Oxycodone
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Amitriptyline
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Duloxetine
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Tramadol
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.