Comparing Flexeril vs Metaxalone
| Flexeril (cyclobenzaprine) | Metaxalone |
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| Flexeril (cyclobenzaprine) | Metaxalone |
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Prescription only
Flexeril is a muscle relaxant that may be used short-term in addition to rest and physical therapy to treat muscle spasms caused by musculoskeletal conditions. Sedation is a common side effect... View more |
Prescription only
Metaxalone is a muscle relaxant that appears to exert its effects through sedation. Taking metaxalone with food can increase its absorption and enhance its effects (such as sedation). Seniors may be... View more |
Related suggestions Muscle Spasm (Involuntary Hypertonicity)
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| More about Flexeril (cyclobenzaprine) | More about Metaxalone | ||||||||
| Ratings & Reviews | |||||||||
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Flexeril has an average rating of 6.1 out of 10 from a total of 237 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 27% reported a negative effect. |
Metaxalone has an average rating of 7.0 out of 10 from a total of 126 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 21% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Flexeril side effects |
View all Metaxalone side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Metaxalone prices |
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| Dosage Forms | |||||||||
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N/A |
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| Brand Names | |||||||||
| Other cyclobenzaprine brands include: Amrix, Comfort Pac with Cyclobenzaprine | Metaxal, Metaxall, Skelaxin | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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72 hours |
3 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category N
Not classified
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 448 drugs are known to interact with Flexeril:
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A total of 317 drugs are known to interact with Metaxalone:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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August 26, 1977 |
August 13, 1962 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.