Comparing Flexeril vs Metaxalone
Flexeril | Metaxalone |
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Flexeril (cyclobenzaprine) | Metaxalone |
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Prescription only
Flexeril is a muscle relaxant that may be used short-term in addition to rest and physical therapy to treat muscle spasms caused by musculoskeletal conditions. Sedation is a common side effect... View more |
Prescription only
Metaxalone is a muscle relaxant that appears to exert its effects through sedation. Taking metaxalone with food can increase its absorption and enhance its effects (such as sedation). Seniors may be... View more |
Related suggestions Muscle Spasm (Involuntary Hypertonicity)
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More about Flexeril (cyclobenzaprine) | More about Metaxalone | ||||||||
Ratings & Reviews | |||||||||
Flexeril has an average rating of 6.0 out of 10 from a total of 232 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 28% reported a negative effect. |
Metaxalone has an average rating of 7.2 out of 10 from a total of 126 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 18% reported a negative effect. |
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Drug Class | |||||||||
Side Effects | |||||||||
See also: Flexeril side effects in more detail. |
See also: metaxalone side effects in more detail. |
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Generic Availability | |||||||||
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all metaxalone prices |
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Dosage Forms Available | |||||||||
N/A |
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Brand Names | |||||||||
Other cyclobenzaprine brands include: Amrix, Comfort Pac with Cyclobenzaprine | Metaxall, Skelaxin | ||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||
72 hours |
3 hours |
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CSA Schedule ** View glossary of terms | |||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||
Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category N
Not classified
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||
A total of 441 drugs are known to interact with Flexeril:
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A total of 312 drugs are known to interact with metaxalone:
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Alcohol/Food/Lifestyle Interactions | |||||||||
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Disease Interactions | |||||||||
First Approval Date | |||||||||
August 26, 1977 |
August 13, 1962 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||
N/A |
N/A |
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More Information | |||||||||
Patient resources | |||||||||
Professional Resources | |||||||||
Related Treatment Guide | |||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.