Flexeril Interactions
There are 448 drugs known to interact with Flexeril (cyclobenzaprine), along with 2 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 92 are major, 350 are moderate, and 6 are minor.
- View all 448 medications that may interact with Flexeril
- View Flexeril alcohol/food interactions (1)
- View Flexeril disease interactions (2)
Most frequently checked interactions
View interaction reports for Flexeril (cyclobenzaprine) and the medicines listed below.
- albuterol
- Ambien (zolpidem)
- aspirin
- Benadryl (diphenhydramine)
- clonazepam
- Cymbalta (duloxetine)
- gabapentin
- ibuprofen
- Klonopin (clonazepam)
- levothyroxine
- lisinopril
- Lyrica (pregabalin)
- meloxicam
- metformin
- Neurontin (gabapentin)
- Norco (acetaminophen / hydrocodone)
- omeprazole
- oxycodone
- prednisone
- Singulair (montelukast)
- Synthroid (levothyroxine)
- Topamax (topiramate)
- tramadol
- trazodone
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Flexeril alcohol/food interactions
There is 1 alcohol/food interaction with Flexeril (cyclobenzaprine).
Flexeril disease interactions
There are 2 disease interactions with Flexeril (cyclobenzaprine) which include:
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More about Flexeril (cyclobenzaprine)
- Flexeril consumer information
- Compare alternatives
- Reviews (237)
- Drug images
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Generic availability
- Support group
- Drug class: skeletal muscle relaxants
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
