Comparing Estradiol vs Vagifem
| Estradiol | Vagifem (estradiol) |
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| Estradiol | Vagifem (estradiol) |
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Prescription only
Estradiol is a synthetic form of estrogen that may be given for several different indications, including the relief of menopausal symptoms or low estrogen levels caused by other conditions. Its use... View more |
Prescription only
Prescribed for Atrophic Vaginitis, Atrophic Urethritis. Vagifem may also be used for purposes not listed in this medication guide. |
Related suggestions Atrophic Vaginitis
Atrophic Urethritis
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| More about Estradiol | More about Vagifem (estradiol) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Estradiol has an average rating of 5.8 out of 10 from a total of 587 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 37% reported a negative effect. |
Vagifem has an average rating of 6.0 out of 10 from a total of 102 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 34% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Estradiol side effects |
View all Vagifem side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Estradiol prices |
View all Vagifem prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Alora, Climara, Delestrogen, Depo-Estradiol, Divigel, Dotti, Elestrin, Estra Pellets, Estrace, Estraderm, Estradiol Patch, Estrogel, Evamist, Femring, Lyllana, Menostar, Minivelle, Vivelle-Dot View more | Other estradiol brands include: Estrace Vaginal Cream, Estring, Imvexxy, Yuvafem | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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16 hours |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 369 drugs are known to interact with Estradiol:
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A total of 237 drugs are known to interact with Vagifem:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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July 23, 1975 |
March 26, 1999 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
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N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.