Comparing Estradiol vs Testosterone
| Estradiol | Testosterone |
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| Estradiol | Testosterone |
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Prescription only
Estradiol is a synthetic form of estrogen that may be given for several different indications, including the relief of menopausal symptoms or low estrogen levels caused by other conditions. Its use... View more |
Prescription only
Prescribed for Hypogonadism - Male, Gender Affirming Hormone Therapy, Gender Dysphoria, Delayed Puberty - Male, Breast Cancer - Palliative, Postpartum Breast Pain, Klinefelter Syndrome. Testosterone... View more |
Related suggestions Gender Dysphoria
Gender Affirming Hormone Therapy
Popular comparisons
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| More about Estradiol | More about Testosterone | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Estradiol has an average rating of 5.8 out of 10 from a total of 587 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 37% reported a negative effect. |
Testosterone has an average rating of 7.3 out of 10 from a total of 533 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 18% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Estradiol side effects |
View all Testosterone side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Estradiol prices |
View all Testosterone prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Alora, Climara, Delestrogen, Depo-Estradiol, Divigel, Dotti, Elestrin, Estra Pellets, Estrace, Estraderm, Estradiol Patch, Estrogel, Evamist, Femring, Lyllana, Menostar, Minivelle, Vivelle-Dot View more | Andro LA 200, Andro-Cyp 100, Andro-Cyp 200, Androderm, AndroGel, Aveed, Azmiro, Delatest, Depandro 100, Depo-Testosterone, Depotest, Duratest, Durathate 200, Everone, FIRST-Testosterone, FIRST-Testosterone MC, Fortesta, Histerone, Jatenzo, Kyzatrex, Natesto, Striant, Testim, Testo-100, Testo-200, Testopel, Testopel Pellets, Testro-LA, Tlando, Undecatrex, Vogelxo, Xyosted View more | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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16 hours |
2 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 369 drugs are known to interact with Estradiol:
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A total of 185 drugs are known to interact with Testosterone:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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July 23, 1975 |
December 24, 1953 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.