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Vagifem and Irritation: What Users Say

Irritation: mentioned by 6 users (5.9%)

Based on user experiences from 102 Vagifem reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

burning 13.7%
headaches 10.8%
pain 7.8%
bloating 5.9%
irritation 5.9%
dizziness 4.9%
hair loss 4.9%
itching 4.9%
back pain 3.9%
vaginal issues 3.9%

Reviews for Vagifem

Commonly mentioned side effects
  • Poo...
  • Taken for 10 years or more
  • March 10, 2020

For Atrophic Vaginitis "Does anyone know if any of the ingredients have changed recently? I have been using Vagifem for almost 15 years once a week and never experienced any burning, but recently, out of the blue, I have burning and cannot understand why, as I am using the brand and not the generic as that caused horrible problems. It works great but not happy with the irritation. Thank you."

8 / 10
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174 Report
  • sam...
  • Taken for less than 1 month
  • April 3, 2020

For Atrophic Vaginitis "I tried Vagifem for two weeks, and while I think it probably helped with soreness inside and plumped things up, it also caused irritation of the urethra, whereby I had a constant pressure, feeling like a need to wee all the time, burning, and stinging inside. I couldn't live with it, and it kept waking me up at night. These symptoms started when I used Vagifem and stopped when I stopped it. I really hope there is an alternative, as I think, for many, Vagifem is a miracle."

5 / 10
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144 Report
  • Msa...
  • Taken for less than 1 month
  • October 14, 2020

For Atrophic Vaginitis "I’m 60 years old and have had multiple urinary tract infections over the years. My doctor just started me on Vagifem 3 weeks ago, as well as progesterone oral tablets. In the last week, the burning, itching, and irritation are driving me crazy. I’m trying to deal with it and applying topical OTC creams as well as natural balms to try and calm my vaginal area down. I’m going back to the doctor tomorrow as I can’t stand this anymore. I was really hoping this medication would work for me, I wonder what the next step will be?"

1 / 10
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71 Report

Frequently asked questions

  • Nic...
  • Taken for less than 1 month
  • July 20, 2020

For Atrophic Vaginitis "Use of Vagifem to address bladder frequency has caused significant irritation, itchiness, and rawness around the vaginal area, as well as thick white discharge. I have discontinued it and am attempting to treat these symptoms, which have progressed to the urethra. Very discouraging, as many women find it very helpful for postmenopausal conditions."

1 / 10
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46 Report
  • Pas...
  • Taken for less than 1 month
  • April 11, 2021

For Atrophic Vaginitis "After suffering with terrible burning, irritation, soreness, and self-medicating with antifungal medication, I have finally found relief with Vagifem. It wasn't thrush at all, it's, for me, a miracle product. After two weeks, I am finally back to normal... Thank you so much, Vagifem!!"

10 / 10
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24 Report
  • Mil...
  • November 15, 2020

For Atrophic Vaginitis "I have been using Vagifem for around 5 years, and initially, it was great, but in the past 12 months, I have also been experiencing burning and irritation and have also started wondering if there has been a change in what is in the pessary."

8 / 10
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24 Report

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