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Vagifem and Itching: What Users Say

Itching: mentioned by 5 users (4.9%)

Based on user experiences from 102 Vagifem reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

burning 13.7%
headaches 10.8%
pain 7.8%
bloating 5.9%
irritation 5.9%
dizziness 4.9%
hair loss 4.9%
itching 4.9%
back pain 3.9%
vaginal issues 3.9%

Reviews for Vagifem

  • Msa...
  • Taken for less than 1 month
  • October 14, 2020

For Atrophic Vaginitis "I’m 60 years old and have had multiple urinary tract infections over the years. My doctor just started me on Vagifem 3 weeks ago, as well as progesterone oral tablets. In the last week, the burning, itching, and irritation are driving me crazy. I’m trying to deal with it and applying topical OTC creams as well as natural balms to try and calm my vaginal area down. I’m going back to the doctor tomorrow as I can’t stand this anymore. I was really hoping this medication would work for me, I wonder what the next step will be?"

1 / 10
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71 Report
  • Nic...
  • Taken for less than 1 month
  • July 20, 2020

For Atrophic Vaginitis "Use of Vagifem to address bladder frequency has caused significant irritation, itchiness, and rawness around the vaginal area, as well as thick white discharge. I have discontinued it and am attempting to treat these symptoms, which have progressed to the urethra. Very discouraging, as many women find it very helpful for postmenopausal conditions."

1 / 10
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46 Report
  • Anonymous
  • January 15, 2025

For Atrophic Vaginitis "I’ve been using this since my hysterectomy back in 2005 with no issues, twice a week, but in the last two months, I’ve noticed burning, which I thought was a UTI infection or bladder infection. Did three rounds of antibiotics. I saw no difference. I also think that they must’ve changed the ingredients in this hormone replacement because I’m experiencing itching, burning, and I feel like I have to pee all the time. It is so bad that I’m waking up at night with a burning sensation."

5 / 10
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2 Report

Frequently asked questions

  • Ang...
  • Taken for less than 1 month
  • July 27, 2022

For Atrophic Urethritis "47 years old. Prescribed by gynecologist. 1 month of being in a nightmare. Severe vaginal swelling, itchiness, burning, pain, and thrush-like symptoms without discharge but severe pain. My vagina since taking this medication feels like an overripe, rotten, juicy tomato. I also have severe water retention and swelling in my lower body. Just waiting until it's out of my system."

1 / 10
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12 Report
  • Sog...
  • November 19, 2020

For Atrophic Vaginitis "I've been prescribed Vagifem 10 for dryness and vaginal itching. I am now on once a week, and I had a good 2 days with no itches. Then on Monday, I did my normal one, and now it's driving me nuts. I really didn't give it a thought that this could be the problem, not the cure. I'm not using it anymore and ringing my GP tomorrow."

1 / 10
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12 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.