Estrace Vaginal Cream Alternatives Compared
| Estrace Vaginal Cream (estradiol) | Vagifem (estradiol) | Estradiol topical |
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| Estrace Vaginal Cream (estradiol) | Vagifem (estradiol) | Estradiol topical |
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Prescription only
Prescribed for Atrophic Vaginitis, Atrophic Urethritis. Estrace Vaginal Cream may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Atrophic Vaginitis, Atrophic Urethritis. Vagifem may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Atrophic Vaginitis, Atrophic Urethritis, Dyspareunia, Overactive Bladder. Estradiol topical may also be used for purposes not listed in this medication guide. |
Related suggestions Popular comparisons
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| More about Estrace Vaginal Cream (estradiol) | More about Vagifem (estradiol) | More about Estradiol topical | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Estrace Vaginal Cream has an average rating of 6.6 out of 10 from a total of 82 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 22% reported a negative effect. |
Vagifem has an average rating of 6.0 out of 10 from a total of 102 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 34% reported a negative effect. |
Estradiol topical has an average rating of 5.1 out of 10 from a total of 487 ratings on Drugs.com. 37% of reviewers reported a positive effect, while 45% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Estrace Vaginal Cream side effects |
View all Vagifem side effects |
View all Estradiol topical side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
| Lower cost generic approved |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Estrace Vaginal Cream prices |
View all Vagifem prices |
View all Estradiol topical prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Other estradiol brands include: Estring, Imvexxy, Vagifem, Yuvafem | Other estradiol brands include: Estrace Vaginal Cream, Estring, Imvexxy, Yuvafem | Estrace Vaginal Cream, Estring, Imvexxy, Vagifem, Yuvafem | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 237 drugs are known to interact with Estrace Vaginal Cream:
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A total of 237 drugs are known to interact with Vagifem:
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A total of 237 drugs are known to interact with Estradiol topical:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
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| First Approval Date | ||||||||||||||||||||||||||
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January 31, 1984 |
March 26, 1999 |
January 31, 1984 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.