Comparing Diclofenac vs Indomethacin
| Diclofenac | Indomethacin |
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| Diclofenac | Indomethacin |
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Prescription only
Diclofenac is an effective medicine for relieving pain but may be associated with an increased risk of cardiovascular and gastrointestinal side effects compared with some other NSAIDs. Prescribed... View more |
Prescription only
Indomethacin relieves inflammation and pain associated with various types of arthritis. The risk of stomach-related and cardiovascular side effects may be higher with indomethacin than that seen... View more |
Related suggestions Rheumatoid Arthritis
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| More about Diclofenac | More about Indomethacin | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Diclofenac has an average rating of 7.3 out of 10 from a total of 695 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 21% reported a negative effect. |
Indomethacin has an average rating of 7.8 out of 10 from a total of 210 ratings on Drugs.com. 70% of reviewers reported a positive effect, while 14% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Diclofenac side effects |
View all Indomethacin side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Diclofenac prices |
View all Indomethacin prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Cambia, Cataflam, Lofena, Voltaren, Xiclo, Zipsor, Zorvolex | Indocin, Indocin IV, Indocin SR, Tivorbex | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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1.8 hours |
4.5 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
Prior To 30 Weeks Gestation
Category D
Positive evidence of risk
Starting At 30 Weeks Gestation See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 443 drugs are known to interact with Diclofenac:
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A total of 419 drugs are known to interact with Indomethacin:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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July 28, 1988 |
June 10, 1965 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.