Comparing Caplyta vs Depakote ER
| Caplyta (lumateperone) | Depakote ER (divalproex sodium) |
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| Caplyta (lumateperone) | Depakote ER (divalproex sodium) |
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Prescription only
Caplyta is an atypical antipsychotic that is used to treat adults with schizophrenia or depression associated with bipolar disorder. Sleepiness is the most common side effect and it should not be... View more |
Prescription only
Prescribed for Bipolar Disorder, Mania, Migraine Prevention, Seizures, Epilepsy. Depakote ER may also be used for purposes not listed in this medication guide. |
Related suggestions Popular comparisons
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| More about Caplyta (lumateperone) | More about Depakote ER (divalproex sodium) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Caplyta has an average rating of 6.6 out of 10 from a total of 184 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 29% reported a negative effect. |
Depakote ER has an average rating of 7.3 out of 10 from a total of 98 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 12% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Caplyta side effects |
View all Depakote ER side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Caplyta prices |
View all Depakote ER prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
Other divalproex sodium brands include: Depakote, Depakote Sprinkles | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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18 hours |
16 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Category D
Positive evidence of risk
When Treating Epilepsy And Manic Episodes Associated With Bipolar Disorder
Category X
Not for use in pregnancy
When Treating Migraine See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 604 drugs are known to interact with Caplyta:
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A total of 424 drugs are known to interact with Depakote ER:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 20, 2019 |
August 04, 2000 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.