Apremilast Alternatives Compared
Apremilast | Otezla | Stelara |
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Apremilast | Otezla (apremilast) | Stelara (ustekinumab) |
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Prescription only
Apremilast is a PDE4 inhibitor that may be used to treat plaque psoriasis, psoriatic arthritis, and oral ulcers associated with Behçet’s Disease. It has been associated with severe diarrhea, nausea, a... View more |
Prescription only
Otezla is a PDE4 inhibitor that may be used to treat adults with plaque psoriasis, psoriatic arthritis, and oral ulcers associated with Behçet’s Disease. It may also be used to treat plaque psoriasis... View more |
Prescription only
Stelara is an immunosuppressant medication that works by binding to two inflammatory cytokines, IL-12 and IL-23, which have been identified as important contributors to chronic inflammation. Stelara... View more |
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More about Apremilast | More about Otezla (apremilast) | More about Stelara (ustekinumab) | ||||||||||||||||
Ratings & Reviews | ||||||||||||||||||
Apremilast has an average rating of 5.2 out of 10 from a total of 466 ratings on Drugs.com. 35% of reviewers reported a positive effect, while 40% reported a negative effect. |
Otezla has an average rating of 5.2 out of 10 from a total of 438 ratings on Drugs.com. 34% of reviewers reported a positive effect, while 41% reported a negative effect. |
Stelara has an average rating of 7.7 out of 10 from a total of 245 ratings on Drugs.com. 71% of reviewers reported a positive effect, while 15% reported a negative effect. |
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Drug Class | ||||||||||||||||||
Side Effects | ||||||||||||||||||
See also: apremilast side effects in more detail. |
See also: Otezla side effects in more detail. |
See also: Stelara side effects in more detail. |
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Generic Availability | ||||||||||||||||||
N/A |
N/A |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Otezla prices |
View all Stelara prices |
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Dosage Forms Available | ||||||||||||||||||
N/A |
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Brand Names | ||||||||||||||||||
Otezla |
N/A |
Other ustekinumab brands include: Otulfi, Pyzchiva, Selarsdi, Wezlana | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||
9 hours |
9 hours |
1291.2 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||
A total of 88 drugs are known to interact with apremilast:
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A total of 88 drugs are known to interact with Otezla:
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A total of 515 drugs are known to interact with Stelara:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | ||||||||||||||||||
First Approval Date | ||||||||||||||||||
March 21, 2014 |
March 21, 2014 |
September 25, 2009 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||
Patient resources | ||||||||||||||||||
Professional Resources | ||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.