Comparing Amiloride vs Spironolactone
| Amiloride | Spironolactone |
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| Amiloride | Spironolactone |
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Prescription only
Prescribed for High Blood Pressure, Edema, Heart Failure, Ascites. Amiloride may also be used for purposes not listed in this medication guide. |
Prescription only
Spironolactone is a diuretic that may be used to remove excess fluid (edema) from the body, lower blood pressure, or treat hyperaldosteronism. It does not cause potassium loss from the body; however... View more |
Related suggestions High Blood Pressure (Hypertension)
Heart Failure (Congestive Heart Failure)
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| More about Amiloride | More about Spironolactone | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Amiloride has an average rating of 5.8 out of 10 from a total of 4 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 50% reported a negative effect. |
Spironolactone has an average rating of 6.9 out of 10 from a total of 703 ratings on Drugs.com. 58% of reviewers reported a positive effect, while 24% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Amiloride side effects |
View all Spironolactone side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Amiloride prices |
View all Spironolactone prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Midamor | Aldactone, CaroSpir | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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9 hours |
37 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 318 drugs are known to interact with Amiloride:
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A total of 382 drugs are known to interact with Spironolactone:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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October 05, 1981 |
January 21, 1960 |
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| WADA Class View classifications | |||||||||||||||||
| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.