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Zoledronic acid User Reviews & Ratings (Page 2)

Brand names: Reclast, Zometa, Aclasta

Zoledronic acid has an average rating of 4.8 out of 10 from a total of 395 reviews on Drugs.com. 34% of reviewers reported a positive experience, while 47% reported a negative experience.

Reviews for Zoledronic acid

  • B Du ...
  • Taken for 2 to 5 years
  • December 5, 2019

Aclasta (zoledronic acid) for Osteoporosis "I had Aclasta once a year 2012 - 2015 due to osteoporosis - Worst mistake I ever made! I have daily incapacitating and severe joint, muscle, and back pain, cannot have a tooth extracted due to osteonecrosis of the jaw (as per the maxillofacial surgeon), my vision became blurred almost immediately after the first session ... my life is no longer my healthy happy life, and I have to endure rhizotomies (which have not helped one bit) because of the back pain. Walking is painful. Shoulders are messed. There is no antidote for this drug either! This was not something we were told beforehand ... we are still deciding to join a class action against the company that manufactures this drug knowing what the side effects are! We would never have said yes! Do your research, guys! Bev - South Africa"

1 / 10
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  • Anonymous
  • Taken for less than 1 month
  • March 2, 2022

Reclast (zoledronic acid) for Prevention of Osteoporosis "I am writing a positive review for Reclast. I have osteopenia and had breast cancer in 2021, for which I now take Letrozole that wears on my bones. I have no other health issues. I had my first infusion on Monday, Feb 28th. I drank plenty of fluids on Sunday and Monday and added Tylenol. After the infusion, I was a little tired and got some rest. I returned to work on Tuesday. My eyes began to feel a little different, but the nurse instructed me to take Claritin if the Ibuprofen did not help. I did have tingling in my fingers for a few minutes, but it went away. I was also exhausted and got some more rest. On Day 3, Wednesday, I was moving a little slow in the morning, took my normal midday walk, and by the afternoon I was back to normal. No other side effects thus far. I pray my bone density increases when I have the bone scan again in 2024."

8 / 10
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  • KMN
  • Taken for less than 1 month
  • May 11, 2022

Reclast (zoledronic acid) for Prevention of Osteoporosis "I have Osteopenia due to being on an estrogen blocker after breast cancer. Prolia was scheduled. When I arrived, I was told insurance wanted Reclast. Therefore, NO prep instructions. I typically drink 64 oz of water every day. Had been taking VitD/calcium for 7 days. Was told Tylenol and loratadine would really help IF I had bone pain. About 6 hours after the 30-minute infusion, I got really tired/sleepy. Also, forehead area headache & low-grade fever. Took XS Tylenol. Felt better, continued hydration. Took Tylenol again about 5 hours later. Went to bed, ribs, shoulders, feet, fingers pain. I'd rate an 8. This is with my normally prescribed pain meds in addition to Tylenol. Hard shaking chills, continuing pain, nausea. More Tylenol, added Zofran for nausea. Only able to sip water... tried ginger ale sips. So I am 6 hours in and writing this while there is a break in chills. Pain now 6. Would not choose this medicine."

3 / 10
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Frequently asked questions

  • Keebler
  • Taken for less than 1 month
  • April 28, 2020

Reclast (zoledronic acid) for Osteoporosis "I am a 58-year-old woman, and yesterday afternoon I had my Reclast intravenous procedure done for the first time. I drank plenty of water (64 oz) the day before, and drank more water (32 oz) the morning of. I took two (2) Extra Strength Tylenol one hour prior to the procedure. The nurse first administered the saline and then the Zoledronic Acid (Reclast). I was also given juice to drink during this time. The whole process took about 40 minutes. I continued to drink plenty of liquids the rest of the day and took two (2) more Extra Strength Tylenol 4 hours later. So far, I have only felt a little tired and slightly achy. I am continuing to drink plenty of water as recommended, and hopefully all is good from here out!"

9 / 10
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  • Kami
  • Taken for less than 1 month
  • January 10, 2020

Reclast (zoledronic acid) for Osteoporosis "Ugh Ugh Ugh - think twice, think three times before EVER taking this stuff. They said minor side effects... NOT!! Never been this sick in my life, vomiting, diarrhea, pain in my joints like a sledgehammer hit me, dizziness - by far worse than when I had influenza. I will NEVER EVER take this again. I hope they have a class-action lawsuit put against them. This is horrible stuff!"

1 / 10
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Are you taking this medicine?

  • Donna
  • August 11, 2020

Reclast (zoledronic acid) for Osteoporosis "I was 64 when I received my first dose of Reclast several months ago for osteoporosis. I was nervous prior, having read about potential side effects, but I figured 3 days of discomfort or pain would be better than a fractured hip or worse. I did follow my doctor's advice and drank plenty of water and took Tylenol. I was very pleased; my symptoms were mild, only slight muscle aches, and I felt fine within 24 hours. Fingers crossed my yearly check-up will reveal an improvement in my bone density. Hopefully, my second dose will be as easy."

10 / 10
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  • Anonymous
  • Taken for less than 1 month
  • July 22, 2021

Reclast (zoledronic acid) for Prevention of Osteoporosis "My mother is very healthy at 83. She takes only one medication for reflux, has full mental capacity, and above-average strength. She had one infusion resulting in severe bone/joint pain, high fever, complete incoherence, a cough, dizziness, and ocular palsy. C-19 was ruled out, as were other diagnoses. After eight months, some of these symptoms continue. Since this Rx is supposed to be given in a series of three, the full effectiveness will not be realized since she obviously will not be getting the remaining two infusions. Do not, under any circumstances, inject this stuff into your body. Find some alternative therapies and supplements instead."

1 / 10
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  • Anonymous
  • Taken for less than 1 month
  • February 11, 2021

Zometa (zoledronic acid) for Osteoporosis "Wonderful!! If you want to say farewell to your already healthy and happy life for months, even for years, take this rubbish, even one dose! You will get paralyzed and achy for so long! DO NOT try this junk, or you will wish for death rather than taking the side effects! Beware! You will experience all the listed side effects! Long-lasting and disastrous! Make your choice!"

1 / 10
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  • Bx56
  • Taken for 1 to 2 years
  • March 30, 2023

Reclast (zoledronic acid) for Prevention of Osteoporosis "I received my first infusion on March 22 and had no problem at all. I did increase my fluid intake the days before and after infusion, and I also took a mild painkiller. I was extremely nervous after reading so many negative reviews on this website. The infusion was pain-free, I had no side effects whatsoever, and felt completely well. I am a 72 year who has severe osteoporosis and this year have been without fractures. I am due my second infusion soon."

9 / 10
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  • Jasmine
  • May 1, 2020

Aclasta (zoledronic acid) for Osteoporosis "I had the infusion about 4 weeks ago, and I felt okay after the infusion, which was around 3 p.m. in the afternoon. However, in bed that same night, around 11 p.m., I started to feel immense cramps in my abdomen, and soon after, I began vomiting. I was shaking uncontrollably and felt very cold; my temperature was over 38 degrees. We drove to the nearest emergency department where I was assessed and immediately put on painkillers and anti-nausea drugs intravenously. After that, I was sent for imaging, and I couldn't walk due to the excruciating pain; I had to be wheeled to radiology for an X-ray. The event seems like a blur, all I remember is the pain. I felt pain for about a week after, the first few days being intense. I will not be going through that again, and I have also blocked calls from my specialist who recommended I should have this done. I still have pain today after nearly FOUR weeks..."

1 / 10
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  • Irene
  • June 24, 2022

Reclast (zoledronic acid) for Prevention of Osteoporosis "I very nearly didn’t have my Reclast infusion because of sites like this that terrify people. I have very bad osteoporosis and I need surgery on my back to hopefully stop my pain and enable me to walk without a walker. I listened to my doctor, read everything about Reclast ( it does give you all information about possible side effects including seeing your dentist prior to getting Reclast ). I am on my 3rd day after my first infusion. I have felt a heavy fatigue, a bit of aching in my body, some pain in various bones that go away fairly quickly, a headache on top of my head that is controlled with Tylenol, and some brain fogginess. As my doctor and the nurse who administered my infusion ( and told me I could leave if I was too nervous ) said to me - hundreds of millions of people take this medication and are fine after feeling a bit rough for about 3 days. The one’s who write about their problems are in vast minority. To others who are scared DON'T read these negative posts !!"

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  • Anonymous
  • Taken for less than 1 month
  • July 6, 2012

Reclast (zoledronic acid) for Osteoporosis "I have read many bad reviews on this treatment, so let me tell you my positive one. I am early 60s, very active, slightly built and failed my bone density scan. Did my research (very important) and found a fabulous young female rheumatologist. After viewing all of my prior Dexa scans, we tried one Fosamax (I had been on Evista for four years prior due to healed multiple ulcers). The Fosamax reaction was very bad, but the gastric distress eased up finally. We decided on the Reclast infusion. The injection was pleasant, the people were great. I went to work. Had a headache for three days, took medicines for the headache but carried on my regular business. This was one week ago. I feel great."

10 / 10
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  • Miss...
  • Taken for less than 1 month
  • July 7, 2019

Reclast (zoledronic acid) for Osteoporosis "Prior to receiving Reclast infusion 9 days ago, I only suffered back pains due to my scoliosis. Flu-like symptoms started exactly 24 hours after my infusion. I thought I was dying because of the severity of the bone aches and chills. I couldn’t walk so I stayed curled in the fetal position with pain. The next day I lay out in the warm weather to feel some relief. They told me that it would only last 2-3 days. Well, yesterday (day 8) I went to urgent care with horrible pain and unable to move my neck, only to be told that I needed to go to the ER to be treated for the pain aggressively. In the ER, I was given pain meds intravenously and sent home to take a muscle relaxer and ibuprofen at the same time. Today is day 9 and I still cannot move my neck or barely walk. When will this let up?! I will NOT do this treatment again."

1 / 10
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  • Anonymous
  • July 1, 2020

Aclasta (zoledronic acid) for Osteoporosis "I am a 24-year-old female runner with osteopenia, and after sustaining a stress fracture in my femoral neck, my specialists suggested an Aclasta infusion. I felt fine the afternoon after the infusion; however, at about 12 am that night, I was woken by severe stomach cramping. When I tried to get out of bed, I had the most intense migraine and nausea; I eventually passed out. I was then bedridden and slept for 40 hours straight, waking every 4 hours to take more pain relief. I even needed oxycodone; the pain was that bad. These severe symptoms eased after 48 hours. However, 1 week before my infusion, I dislocated my right patella, and so it blew up with swelling and pain, and I couldn’t walk, meaning I had to spend the next three days in bed and off work. I couldn’t believe a treatment of this time could have such grotesque side effects; it was honestly a horrific and borderline traumatic experience. I think people should really consider the benefits of an Aclasta infusion before going ahead with it."

2 / 10
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  • jake
  • Taken for less than 1 month
  • June 6, 2019

Zometa (zoledronic acid) for Osteoporosis "For four weeks, I had little to no appetite and periods of tiredness. For the first 3 weeks, I was also in a stupor, tired, and weak every day, with nausea daily. Along with these symptoms, for the first 2 weeks, I had on and off fever, chills, headache, no energy, sweats at night. I felt like I was drugged and was weak, unstable, and sick. I would never, never take Zometa again, and I do NOT recommend it."

2 / 10
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  • Grape...
  • Taken for less than 1 month
  • June 6, 2021

Reclast (zoledronic acid) for Osteoporosis "I’m 54 and almost 3 weeks post my first infusion. Just recently diagnosed with postmenopausal osteoporosis, and doc recommended Reclast as the easiest treatment. The infusion went well, but 24 hours, I started having muscular back pain. It’s not getting better and is fairly excruciating. It feels like back labor, spiking at 7-8 on a 10-point pain scale. After a few days, I called my MD and got muscle relaxants, ibuprofen, and topical NSAIDs (diclofenac), but they’re not really helping. I just started a new job and am trying very hard to work through this, but I’m really getting worried. I need some serious dental work, too, but I’m not really inclined to take the assurances that it will all be fine in a couple of months at face value right now. I was not warned about preparing before with water, Vit D and calcium, don’t know if it would have helped. I’ll be glad if my bone density increases, but in any case, there’s no way I’m taking this again."

1 / 10
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  • Sarah
  • Taken for 2 to 5 years
  • April 8, 2019

Aclasta (zoledronic acid) for Osteoporosis "My 85-year-old mother has been having this infusion every year for the last 4 years. The first time she had it, she was quite sick afterwards with body aches and fatigue. And wishing she never had it. The doctor said next time to ask for it to be slowly administered. And it did make a huge difference with no side effects. And now she makes sure it gets administered slowly. Not everyone seems to know about this."

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  • Denmark
  • January 8, 2020

Reclast (zoledronic acid) for Osteoporosis "I had my Reclast infusion about two months ago. The first week was fine, then it was downhill from there. I get chills, dizziness, a terrible cough to the point of almost choking. The fatigue is awful; I sleep 12-13 hours per day and don’t want to get out of bed. I have been to the doctor, and they have checked me for everything under the sun, including CT scans, and nothing is wrong with me. I will never do this again, and I sure hope these symptoms don’t last the entire year."

1 / 10
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  • Breezzy
  • Taken for 2 to 5 years
  • October 13, 2018

Reclast (zoledronic acid) for Osteoporosis "My first two infusions went okay. My DEXA did not really change. Then I had my third infusion, and everything but my bone density changed. I now have an irregular EKG and heart flutters, and high blood pressure that came out of nowhere. I have felt totally unwell, dizzy, and unsteady at times. I feel that I have been poisoned. Shame on me for believing big pharma could help. Just take your calcium citrate and vitamin D; that's all you really need for your bone health. Reclast is just another poison to ruin your health."

1 / 10
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  • 2023
  • Taken for less than 1 month
  • March 25, 2023

Reclast (zoledronic acid) for Prevention of Osteoporosis "I had my first and only Reclast infusion 23 days ago. About 9 hours after the infusion I started feeling ill, I had terrible chills, shaking violently for two hours. At 2:00 a.m. I went to the ER with a fever of 102.4 and pain everywhere. I had heart surgery to repair my mitral valve 2 1/2 years ago and have been taking an arrhythmia drug for 2 years and I’ve been fine. Since the infusion I am tired, I have a fib and bigeminy several times a day, chest pain, and unbearable calf pain. This drug has ruined my health and my life. Do not take it."

1 / 10
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  • Vimm
  • Taken for less than 1 month
  • December 31, 2019

Reclast (zoledronic acid) for Osteoporosis "Had my first Reclast infusion on 12/20/19. The worst I have ever felt, and I live with chronic pain every day! But this was the most uncomfortable feeling I’ve ever been through, with having had the flu when I was in my early 30s. This medicine made me feel like I had an elephant sitting on my chest, approximately 12 hours after the infusion, along with flu-like symptoms! I was bedridden the whole next day and still a week and a half, still have pain in my chest. I could not eat and had to force trying to drink water, to try and take Tylenol for the pain, which didn’t help!!! Please read reviews on this medicine before you get it!! I WILL NEVER HAVE THIS AGAIN!!!!"

1 / 10
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  • Ghost
  • Taken for 1 to 6 months
  • January 26, 2020

Reclast (zoledronic acid) for Osteoporosis "I had the Reclast infusion in Oct 2019. During the infusion, I was so thirsty, I just kept chugging water. I went straight to work afterwards and was thrilled that I felt fine. I even went out for a nice dinner. However, exactly 12 hours after the infusion, flu-like symptoms hit me like a brick. I could barely move. Luckily, it only lasted about 36 hours. It was scary because you do wonder if you're ever going to feel well again. I don't know if this is related, but in my mind it is - about 3 weeks later, I had horrible acid reflux and bloating, I could barely eat. I could only take small sips of soup. This lasted nearly 2 months. I am improving now. I believe this is a side effect, although it is not listed as a possible side effect. Well, every person reacts differently. I do not plan to take this again. Good luck! Tough decisions here."

6 / 10
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  • Plant...
  • August 27, 2013

Reclast (zoledronic acid) for Osteoporosis "I had my first Reclast IV injection last winter, just prior to the holidays. I had about 5 days of severe flu symptoms and seriously considered not repeating the injection the next year. However, my bone scan was so positive and even with several falls, I have not broken anything. Prior to the Reclast, I had, in 2 years, a fractured hip, wrist, and ankle. Surgery on the hip showed a femur like Swiss cheese and the severe fall seriously impacted my life. This year I'm 70 and preparing for my second IV, seeing a dentist to make sure I don't have any serious issues that need to be dealt with. I also quit taking steroid spinal IVs for chronic pain this year, thinking I could deal with the pain and perhaps not have further breaks. I endorse Reclast."

9 / 10
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  • Mish
  • Taken for less than 1 month
  • February 28, 2019

Aclasta (zoledronic acid) for Osteoporosis "My husband was administered Aclasta on 18 Feb 2019. He started feeling feverish, vomiting, shivering, and severe weakness the next day. He could not even walk. After nine days, he is still feeling very weak and not able to do any work. He was healthy before the infusion. We don't know what to do. We are helpless. Seeing my husband's condition, would not recommend Aclasta to anybody. Can someone help?"

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  • Joni
  • Taken for less than 1 month
  • October 12, 2019

Reclast (zoledronic acid) for Prevention of Osteoporosis "HORRIBLE!! The injection itself was a piece of cake, and the first night had zero problems. Night #2 started off with some muscle aches. NBD (no big deal), the doctor warned of flu-like symptoms. The aches got worse as the evening progressed. I got up feeling very restless, and when I touched the floor, I realized I was FREEZING COLD! The coldest I have ever felt in my life. At the same moment, starting with my feet, I had severe muscle cramping up the entire length of my body. I was scared to death! I thought I was having a stroke or something as I lost complete control of my body. I lay back down and willed myself not to pass out. I’m not sure whether I did or not! Several hours later, I was able to get up and take some Motrin to help with the muscle pain. Semi-normal by morning, but completely freaked out! Now, several weeks later, I am having massive hair loss! This drug SUCKS!"

3 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.