Zoledronic acid User Reviews & Ratings (Page 5)

Brand names: Reclast, Zometa, Aclasta

Zoledronic acid has an average rating of 4.8 out of 10 from a total of 395 reviews on Drugs.com. 34% of reviewers reported a positive experience, while 47% reported a negative experience.

Reviews for Zoledronic acid

sunsh...
Taken for 1 to 6 months
September 15, 2016

Reclast (zoledronic acid) for Osteoporosis "Received dose at 11 a.m., by 10 p.m. that night I had fever, chills, severe pain in back. I was extremely ill for 3 days, such a severe headache I couldn't open my eyes. A week later my hands suddenly swelled to the point I could not use them. Now nearly 3 months later I am in physical therapy to try to regain the strength in my legs. Other side effects were less severe, such as jaw pain for a few weeks. I would never ever take this medicine again."

1 / 10

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80 Report

Suz
Taken for 1 to 6 months
May 7, 2019

Reclast (zoledronic acid) for Osteoporosis "I had the Reclast infusion on April 4th and 12 hours later I had severe chills (shaking so bad I couldn't close my mouth to take my temp), fever. Lasted for 6 hours. Then I was sick to my stomach for the next day with severe pain in legs (hard to get up from a chair) and my hands (hurt to write). Then I started with "cold" sinus/bronchial infection which sent me to urgent care for inhaler and cough medicine. Back to Doctor after 5 days for antibiotics and I'm still sick one month later. Now jaw pain on left side and my teeth hurt. I will NEVER take reclast EVER again. I hope you won't either!!!"

1 / 10

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59 Report

whata...
Taken for less than 1 month
September 2, 2020

Reclast (zoledronic acid) for Osteoporosis "Female 78 yrs young! first Reclast infusion in July 2020, no one told me to drink extra water prior to infusion, while still at the center I started getting a bad stomach ache which lasted 3 days, it was BAD, the first 18 hours unbearable- Dexa score 2018 -2.5, 2019 -2.9, July -3.2- I've taken 1,200 Calc w D3 for years, also Magnesium daily, eat well, osteoarthritis and porosis in feet really bad, fingers and hips- feeling fine now, no other side effects noted"

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47 Report

Frequently asked questions

Insights from a Pharmacist about Osteoporosis Treatments

Melissa
July 26, 2020

Reclast (zoledronic acid) for Prevention of Osteoporosis "Just had my first Reclast infusion on July 23,2020. Just getting out of bed for the first time in 3 days I have side effects of the worst pain ever in my bones and my head, hands , back ! I felt like every bone in my body was punched, kicked and crushed . I could feel each bone ache individually ( if that makes sense ) Headache was so bad I got sick . However, day 3 is the magic number and I am feeling much better ;). It has been very bad , but I have made it through with lots of rest laying in bed watching movies. I think for me it was worse then chemo yuck feeling . *** don’t know how effective until next year"

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48 Report

Jms
Taken for 6 months to 1 year
April 6, 2022

Zometa (zoledronic acid) for Hypercalcemia of Malignancy "I agree with other reviewers, you will experience all side effects listed. I have had 7 infusions (1 monthly) for 1 year. After infusion I’m fine for a day. Usually 1-2 weeks after I will be extremely tired with bloating and burning skin on abdomen. Side effects vary monthly."

2 / 10

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31 Report

Are you taking this medicine?

PAW
Taken for less than 1 month
December 9, 2019

Aclasta (zoledronic acid) for Osteoporosis "I had Aclasta on the 21st November2019. No side affects for about a week now everyday I wake up with side effects with bone pain and muscle pain. Sometimes my feet are very sore. Hope all this stops soon. I will not be having anymore Aclasta."

4 / 10

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52 Report

Blond...
May 22, 2020

Zometa (zoledronic acid) for Osteoporosis "I will never try Zometa again. I had horrific side effects, I passed out 7 hours after home from infusion, my neighbor called paramedics, my blood pressure dropped to 80/58. I’ve had full body ache, headache, sweats and chills for 3 days so far."

1 / 10

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48 Report

mcvolta
Taken for less than 1 month
December 17, 2023

Reclast (zoledronic acid) for Osteoporosis "I am 72, and my last DEXA scan showed that my bone density was now osteoporosis. My choices were Reclast or Prolia. I had taken Actonel and Fosamax for a number of years and was taken off of Fosamax due to acid reflux. I hadn't had any osteoporosis medication for the past four years. After discussing this with my doctor, I decided to try Reclast first. I was mostly concerned with side effects reported from each drug, so I was anxious about getting the treatment. I read the reviews and followed the advice from others about drinking plenty of water to stay hydrated and taking Tylenol. The nurse who administered my medication said that she had been giving this med for years now, and very few patients had reported any problems, and most of those were muscle pain that lasted a few days. I am happy to report that I have had no side effects from Reclast. I will find out in a year if my bone density improves, but do not be afraid of this med if you need to take it."

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11 Report

FatCh...
Taken for less than 1 month
October 30, 2014

Reclast (zoledronic acid) for Osteoporosis "Had my infusion yesterday. I drank a few glasses of water in the morning and took an ibuprofen during the treatment. I had expected the '3 days of flu-like symptoms' and even scheduled sick time to be prepared. Zero side-effects, no aches or pains, nothing...but still taking the time off so I can have fun. My stats: 50, 100#, just finished 2 years of Forteo, I take 1200mg Calcium a day plus an Rx Vitamin D each month."

6 / 10

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88 Report

Henry
Taken for less than 1 month
September 2, 2019

Reclast (zoledronic acid) for Osteoporosis "After being reassured by 2 physicians, one an MD, another Oncologists: that this option for infusion would offset any negative side effects for the benefit would receive. Couldn't have been more untrue in my case. After infusion bedridden for 3 days with limited movement due to extremely painful joints. Been 8 days now & I'm just now getting back on my feet but weak. Please get multiple opinions from all before considering this medication. Never again."

1 / 10

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52 Report

Mano
July 17, 2020

Reclast (zoledronic acid) for Osteoporosis "55 year old with osteoporosis (genetic predisposition as well as early menopause). Had my first infusion yesterday. Did prep with lots of water and Tylenol (hence up peeing throughout the night). Today I am sore, stiff, headache and fatigued. But all manageable with Tylenol and Advil (taken 2 hours apart). Deep breaths hurt and took an almost 3 hour nap today (at least during pandemic I don’t have to work)."

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45 Report

CJano
Taken for 6 months to 1 year
May 1, 2021

Reclast (zoledronic acid) for Osteoporosis "I have been in pain for over 6 months after Reclast. Picking up a tiny cup of water sends pain to my back. I am okay if resting. Pain in all joints and bones. I am 82. Never a bit of pain prior to this infusion. I have never fallen as an adult. I was never told by doctor to drink water a day prior. I would like to join a lawsuit if there is one."

1 / 10

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38 Report

Arose
Taken for less than 1 month
May 22, 2022

Reclast (zoledronic acid) for Prevention of Osteoporosis "It’s been a little over 48 hours since my 15 minute Reclast infusion. It was easy. No side effects in the first 24 hours then some pain in my hip area. I took ibuprofen and it went away in about an hour. Woke up the next morning with a sore throat and a little more pain in my hip but took ibuprofen again it did the trick. This was my first infusion. If I get a good outcome I’ll definitely do it again."

10 / 10

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28 Report

Recast...
May 7, 2017

Reclast (zoledronic acid) for Osteoporosis "Had the infusion twice. The only side effect the 1st time was a slight headache. The 2nd time, no side effects at all. I highly recommend having this. Make sure you are well hydrate the day of the procedure."

10 / 10

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69 Report

Connie...
Taken for less than 1 month
February 7, 2020

Reclast (zoledronic acid) for Osteoporosis "Feb 7th Update . I did my original post on Jan 30 under the same name, about having the Reclast infusion on Jan.27, 2020. Just so you know how long the side effects for Reclast last I am still having pain in my legs, blurred vision, some nausea and headache, but able to get up and down the stairs now eating a little bit better. Starting to feel a little better."

4 / 10

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48 Report

Laura
Taken for less than 1 month
July 31, 2022

Reclast (zoledronic acid) for Prevention of Osteoporosis "I had my first infusion of Reclast on a Wednesday afternoon. By 3 AM Thursday morning I had fever, chills and extreme body aches. Nauseated and a headache. Pretty extreme, took Tylenol got a little relief. The next 24-48 hrs. has been pretty terrible, still slowly recovering. Will not do this infusion ever again. I was told by the nurses well you might feel a little achy that wasn’t even close to how bad I felt."

2 / 10

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26 Report

Phyli...
Taken for less than 1 month
March 17, 2014

Reclast (zoledronic acid) for Osteoporosis "I had my infusion on Friday. My doctor gave me Tylenol at that time and said take one twice a day for 3 days. On Sunday, I woke up with some leg muscle pain. I took 2 Tylenol and an Aleve later on in the morning. Felt fine all day and I resumed my gym workouts on Monday. This was a breeze."

10 / 10

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89 Report

Connie...
January 30, 2020

Reclast (zoledronic acid) for Osteoporosis "Had my infusion on Monday Jan.27, 2020 Was just tired and weak at first, then in the middle of the night I had the most excruciating pain in my bones all night until morning . Doctor then gave me tramadol which helped the pain but the next day I vomited all day long. It’s been 4 days and I’m nauseous my head still hurts have no strength to get out of bed or eat much."

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47 Report

SueBu...
Taken for 2 to 5 years
June 5, 2013

Zometa (zoledronic acid) for Osteolytic Bone Metastases of Solid Tumors "I have been receiving Zometa via IV infusion for about 3 years now. At first, three weekly, then after about a year, four weekly. I have breast cancer and bone metastasis. If I take the infusion over 15 minutes, during the following day I will begin with severe vomiting and flu symptoms, which last for two days and nights, after which I'm fine. However, if I have the infusion over 30 minutes - as advised on the internet way back in the early days of my treatments - I have NO side effects whatsoever, no sickness, no aches, and pains! I have spoken to other women who have experienced the same - take the infusion slower, drink plenty of water, and you might just find your horrid side effects disappear!"

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90 Report

mcm
Taken for 6 months to 1 year
February 25, 2023

Reclast (zoledronic acid) for Osteoporosis "Follow up on initial reclast first taken 3/ 2022. I was never informed of any prep to do beforehand, I suffered violent severe side effects for 8 days immediately after the reclast infusion I was so ill I was unable to call 911 and get myself to a hospital. I was completely incapacitated with severe bone pain, rolling head-to-toe cramps, extreme flu-like symptoms, chills, fevers, and a blinding headache that lasted for 8 days. Now one year after I am still experiencing severe and extreme bone pain that many times causes me to be unable to lift my arms and has impacted my quality of life. Additionally, I suffered another compression fracture with zero exertion in June of 2022. I also require several implants and refuse to potentially destroy my jaw. Reclast side effects outweigh any possible benefits. I will be 57 yrs old this year, and prior to 2022 had no knowledge I had osteoporosis. I pray I have no further issues!"

1 / 10

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19 Report

Bammy
Taken for less than 1 month
November 19, 2019

Reclast (zoledronic acid) for Osteoporosis "Had my first infusion Nov 15,2019. I started getting the flu like symptoms about 8 hours later. Thought I was the end of me. I shook for 2 days with chills. Couldn’t pick my arm up to get the Tylenol off my nightstand, 5 hours later I finally got them and every blanket I owned. It hurt so much. Then started with throw up and diarrhea. It’s been 4 days and I’m still in bed beyond tired. Not sure how to rate the medicine cuz it hasn’t started to work yet. But the side effects are really bad. Make sure you have lots of water..Gatorade and Tylenol or pain meds..you’ll need them"

6 / 10

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47 Report

AvoidAt...
Taken for less than 1 month
April 26, 2023

Reclast (zoledronic acid) for Prevention of Osteoporosis "I had the infusion early Friday afternoon. Within 3 hours, I had a very intense headache. By midnight, the headache was unbearable, and I also experienced deep pain, chills, dizziness, and chest pain that felt like a cement block between the ribs. On Saturday, all these issues persisted, along with a fever. On Sunday, I still had the same symptoms and also developed numbness in my legs, feet, arms, and hands. I also noticed loads of small, tiny spots on my palms and fingers. On Monday and Tuesday, the symptoms persisted, and I was unable to get out of bed. Concerned about all these issues, I called my doctor, who prescribed a 6-day cycle of steroids to try to flush out the medication. While I am aware that no one can predict how a body will react to any medication, simply saying that you may feel flu-like symptoms understates what I have been going through. I have never regretted a medical decision more than this one! Please research and know that this has caused havoc on my body, and who knows if I'll ever be the same again."

1 / 10

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17 Report

Avara
Taken for 2 to 5 years
November 13, 2016

Aclasta (zoledronic acid) for Osteoporosis "I have Osteogenesis Imperfecta. After getting Aredia for years and not seeing much improvement (maybe it prevented deterioration), I received Aclasta for 2 years and my bone density went from very fragile to just below average. That was 2 years ago. No side effects and no deterioration as of yet. I'm very happy to be repaired."

10 / 10

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67 Report

Jaclash
Taken for less than 1 month
June 16, 2017

Zometa (zoledronic acid) for Osteolytic Bone Metastases of Solid Tumors "Had my first dose on Monday 12th June 2017. I was fine Monday night so felt quite positive. Woke up Tuesday feeling like death! Wednesday felt better but had a painful red swollen left eyeball. Long story short. I'm in agony with my eye and no one knows what to do! The hospital tried to say it wasn't a side effect! It's a very rare side effect but it is one! And the fact they know nothing about it or how to deal with it is disgusting and frightening! I will not be having this treatment again and will be taking this further!! They should not be giving people something if they don't know everything about it!"

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62 Report

Lala
Taken for less than 1 month
August 29, 2020

Reclast (zoledronic acid) for Osteoporosis "Had my first Reclast infusion on Wed Aug 26, my whole body hurt that night and the next morning could not walk, my sciatic nerve also kicked in. Today is Fri the Aug 28 still have trouble walking and need assistance, was not told about water or pain reliever before the infusion, hoping this goes away soon, I'm 56 years old with dex score of -34 in my L-1 thur L-5 and boarder line osteoporosis in my left femeral neck,"

1 / 10

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39 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.