Zanubrutinib User Reviews & Ratings

• Coz...
• Taken for 1 to 6 months
• December 12, 2023

Brukinsa (zanubrutinib) for Chronic Lymphocytic Leukemia "I was diagnosed with CLL a little over 3.5 years ago at age 70. We were on a 'wait and see' routine up until about 6 weeks ago. My oncologist said I should go on treatment and he recommended Brukinsa. Being a little 'freaked' out about having to go on treatment, I contacted MD Anderson. My wife and I flew to Houston and had an array of blood tests done. 19 vials. The Dr. was very kind and patient and explained CLL and the clinical trials they are now conducting. I asked him what he would do in my situation, he said to stay the course on Brukinsa as it is one of the newest of the BTK inhibitors. So, for right now, I'm sticking to Brukinsa. As far as side effects, I haven't noticed any."

• Mar...
• Taken for 1 to 6 months
• April 26, 2024

Brukinsa (zanubrutinib) for Chronic Lymphocytic Leukemia "Taking it since November 2023 for SLL. Within a week, all bulky adenopathy melted away with transient high lymphocyte blood levels, but normal range in a few months. I have mild fatigue and low immune function, but have not been ill otherwise. Constipation managed with Metamucil and diet changes. I noticed slightly increased bleeding during oral care and just noticed petechiae on my legs today, very minor. Labs have been good, but decreasing neutrophils, basophils, eosinophils. 160 mg bid"

• Sid...
• Taken for 6 months to 1 year
• June 6, 2024

Brukinsa (zanubrutinib) for Waldenström Macroglobulinemia "Was totally fatigued and had severe weight loss. Two weeks on Brukinsa, noticed the difference. Taking 160mg in the morning and 160mg in the evening. After taking these for one year, my weight is back to normal, no serious side effects, did have some bruising at the start. Healed quickly."

• JGT...
• Taken for less than 1 month
• July 9, 2024

Brukinsa (zanubrutinib) for Chronic Lymphocytic Leukemia "I just started Brukinsa 3 weeks ago. I take 320 mg in one dose in the morning. It has not caused any discomforting symptoms. I had lab work done today, and my lymphocyte count went from 171 x 1000 down to 65 x 1000. My platelets are well within the normal range, but my hemoglobin went from 10 down to 9.5."

• Gla...
• Taken for 1 to 2 years
• September 2, 2023

Brukinsa (zanubrutinib) for Mantle Cell Lymphoma "Brukinsa put me in remission within a 6-month timeframe of starting the treatment. Benefits are it has kept me in remission for almost 12 months. Very pleased with the results. As for side effects, I've experienced rashes, musculoskeletal pain, muscle spasms, fatigue, and occasional stomach constipation or diarrhea. I take 320 mg per day, 2 in the morning and 2 in the evening."

• Vic...
• Taken for 1 to 6 months
• September 26, 2024

Brukinsa (zanubrutinib) for Chronic Lymphocytic Leukemia "My mom, 74 years old, started taking Brukinsa recently on Aug 20, 2024. All swelling lymph nodes on the collarbone and underarms are gone. She is losing a little weight, no side effects. I have noticed some skin dryness and wrinkles around the neck, a little fatigue, but overall, much better than before treatment. Thanks to the lymphoma clinic in Fred Hutch Cancer Center, Seattle, and thanks to the Beigene company and their support team."

• Tin...
• Taken for 6 months to 1 year
• August 19, 2024

For Waldenström Macroglobulinemia "I had been on Watch and Wait status for my Waldenstrom's macroglobulinemia for the two years after diagnosis. While I didn't have any symptoms, my blood work for my kidney function started to come back abnormal as my IGM continued to rise. We started treatment to see if the kidney numbers would improve. They improved after one month, and my IGM dropped considerably. It's been nine months since treatment started, and I feel completely normal. I have lots of energy, and it's hard to believe I have an incurable blood cancer. The only side effects that I have noticed include bruising more easily and small purple/reddish pin-sized dots on my skin occasionally. Neither bothers me."

• Anonymous
• Taken for 1 to 2 years
• February 3, 2024

Brukinsa (zanubrutinib) for Chronic Lymphocytic Leukemia "Side effects come and go but are common, lasting a few hours or a couple of days, like joint and muscle pain, especially to areas that were previously injured. Otherwise, no problem handling them. Remission occurred in six months."

• Joh...
• Taken for 2 to 5 years
• April 10, 2024

Brukinsa (zanubrutinib) for Waldenström Macroglobulinemia "I have been using Brukinsa for over two years and I am now having difficulties with weight gain and lymphedema in my legs and feet to the point that I am having difficulties walking and getting in and out of a seat, especially in cars. I am looking for help with little success."

• DRT...
• Taken for 1 to 2 years
• March 29, 2024

Brukinsa (zanubrutinib) for Chronic Lymphocytic Leukemia "Continuing to work extremely well after one year. Some fatigue, and presently having persistent nasal congestion and sneezing, but not sure if it is from the medication. All of my blood counts returned to normal after one month, and have remained normal."

• S s...
• Taken for 1 to 6 months
• August 27, 2023

For Waldenström Macroglobulinemia "I am 81 years old. I was experiencing weight loss, no energy, shortness of breath, and feeling constantly tired. I am on my fourth bottle of Brukinsa and my symptoms are gone. I am gaining weight again. No side effects other than bruising easily, which could be attributed to my age."

• Nan...
• Taken for 6 months to 1 year
• July 1, 2024

For Waldenström Macroglobulinemia "I have been taking 320 mg daily for 6 months. So far, so good - no negative side effects, and my labs show improvement. My overall experience is positive - especially when comparing it to other treatments that included steroids. Just hoping it continues to work!"

• Bri...
• Taken for 6 months to 1 year
• March 6, 2024

Brukinsa (zanubrutinib) for Waldenström Macroglobulinemia "My doctor changed from Imbruvica to Brukinsa approximately 8 months ago. My IgM did improve slightly, but a terrible skin rash appeared all over my body accompanied with uncontrollable itching. I blame Brukinsa for that. I now need advice about what to take for my Waldenstrom's condition with fewer side effects."

• ssg...
• Taken for 1 to 6 months
• December 20, 2022

For Waldenström Macroglobulinemia "My IGM has gone from 2400 to 285 in 3 months after going from 4000 to 2400 doing R-chop for 4 months. I feel much much better than I have for the last 9 months. Some of my problems I'm blaming the R-chop. The only problems I'm having are fatigue and joint pains. This could be my 75 birthday and the R-chop but I really didn't have any real pain in my thumbs until I started on the zanubrutinib. And it seems to get much worse. My hands are very swollen overnight. I'm not able to hold a golf club."

• Nic...
• Taken for 1 to 6 months
• June 12, 2024

For Chronic Lymphocytic Leukemia "Diagnosed in 2013 and had treatment in 2019 with bendamustine-rituximab. I was in remission for nearly 3 and a half years when my CLL returned. I have now completed my first month of zanubrutinib. No side effects so far and noticed that the fatigue I was feeling has significantly lessened."

• dmp...
• Taken for less than 1 month
• February 1, 2024

Brukinsa (zanubrutinib) for Chronic Lymphocytic Leukemia "I started on Brukinsa on the 5th. I marked improvement in my headaches. I was on Imbruvica since March of 21, starting at 420mg and then reduced to 280mg in hopes of reducing headaches. There was no improvement, so I was taken off it totally on November 15th. I still have issues with bad headaches, but the intensity isn't as bad."

• Ste...
• Taken for 1 to 6 months
• August 7, 2024

For Chronic Lymphocytic Leukemia "I started Brukinsa about two months ago after tests revealed that the CLL had invaded my bladder and prostate. My oncologist first started me on Obinutuzumab + Venetoclax, but I had a severe reaction, and she changed my protocol to Brukinsa. To date, I have had no discernible side effects, and I have noticed that my lymph nodes are shrinking. I feel generally good, and my energy level remains high."

• Way...
• Taken for 6 months to 1 year
• July 27, 2024

Brukinsa (zanubrutinib) for Mantle Cell Lymphoma "I have been taking it for 7 months. There are no problems with side effects. I take 80 mg twice a day. There is mild depression of platelets, WBC, and a good neutrophil count. It works great, all tumors disappeared within 4 months."

• DrM...
• Taken for less than 1 month
• August 25, 2024

For Mantle Cell Lymphoma "Started 3 weeks ago for MCL. 160 mg BID. Palpable adenopathy essentially already resolved (!) Side effects = bruising, rash, mild purpura on arms, mild petechiae on face and legs, occasional nausea. Interesting side effects = 1.) voice change (much lower, sound like Yoda with a cold) which begins about 2 hours after taking a dose and lasts for about an hour. Very repeatable. 2.) eyelashes appear to be getting longer."

• Ana...
• April 19, 2024

Brukinsa (zanubrutinib) for Waldenström Macroglobulinemia "I have been taking it for 3+ months and have no bad side effects. It is reducing my M-spikes and most of my blood values have moved back into normal ranges. I couldn't be more pleased!"

• Ste...
• Taken for less than 1 month
• March 3, 2024

Brukinsa (zanubrutinib) for Chronic Lymphocytic Leukemia "4 weeks so far so good. No side effects. Lymphs have gone down."

• Bru...
• Taken for 1 to 6 months
• February 3, 2024

Brukinsa (zanubrutinib) for Chronic Lymphocytic Leukemia "Already 4 months on Brukinsa. All enlarged lymph nodes have disappeared. Very minor side effect - upper right foot skin sensitivity. So far, it has worked very well for me."

• Bud...
• Taken for 1 to 2 years
• May 10, 2024

Brukinsa (zanubrutinib) for Waldenström Macroglobulinemia "Taking it for over a year and I feel great. No side effects except some occasional bruising. IGM numbers are definitely lower than they were to start and approaching normal."

• Anonymous
• Taken for less than 1 month
• June 3, 2024

Brukinsa (zanubrutinib) for Chronic Lymphocytic Leukemia "At times, after taking Brukinsa, seem to feel tired."

• jus...
• Taken for 1 to 6 months
• March 17, 2024

For Chronic Lymphocytic Leukemia "Bruising. Lethargy. More skin cancer. I think it's working, but I hate it. I've thrown up a few times after taking it. I'm tired all the time and it makes me grumpy."