Zanubrutinib for Chronic Lymphocytic Leukemia User Reviews

• Coz...
• Taken for 1 to 6 months
• December 12, 2023

Brukinsa (zanubrutinib) "I was diagnosed with CLL a little over 3.5 years ago at age 70. We were on a 'wait and see' routine up until about 6 weeks ago. My oncologist said I should go on treatment and he recommended Brukinsa. Being a little 'freaked' out about having to go on treatment, I contacted MD Anderson. My wife and I flew to Houston and had an array of blood tests done. 19 vials. The Dr. was very kind and patient and explained CLL and the clinical trials they are now conducting. I asked him what he would do in my situation, he said to stay the course on Brukinsa as it is one of the newest of the BTK inhibitors. So, for right now, I'm sticking to Brukinsa. As far as side effects, I haven't noticed any."

• Mar...
• Taken for 1 to 6 months
• April 26, 2024

Brukinsa (zanubrutinib) "Taking it since November 2023 for SLL. Within a week, all bulky adenopathy melted away with transient high lymphocyte blood levels, but normal range in a few months. I have mild fatigue and low immune function, but have not been ill otherwise. Constipation managed with Metamucil and diet changes. I noticed slightly increased bleeding during oral care and just noticed petechiae on my legs today, very minor. Labs have been good, but decreasing neutrophils, basophils, eosinophils. 160 mg bid"

• JGT...
• Taken for less than 1 month
• July 9, 2024

Brukinsa (zanubrutinib) "I just started Brukinsa 3 weeks ago. I take 320 mg in one dose in the morning. It has not caused any discomforting symptoms. I had lab work done today, and my lymphocyte count went from 171 x 1000 down to 65 x 1000. My platelets are well within the normal range, but my hemoglobin went from 10 down to 9.5."

• Anonymous
• Taken for 1 to 2 years
• February 3, 2024

Brukinsa (zanubrutinib) "Side effects come and go but are common, lasting a few hours or a couple of days, like joint and muscle pain, especially to areas that were previously injured. Otherwise, no problem handling them. Remission occurred in six months."

• DRT...
• Taken for 1 to 2 years
• March 29, 2024

Brukinsa (zanubrutinib) "Continuing to work extremely well after one year. Some fatigue, and presently having persistent nasal congestion and sneezing, but not sure if it is from the medication. All of my blood counts returned to normal after one month, and have remained normal."

• Vic...
• Taken for 1 to 6 months
• September 26, 2024

Brukinsa (zanubrutinib) "My mom, 74 years old, started taking Brukinsa recently on Aug 20, 2024. All swelling lymph nodes on the collarbone and underarms are gone. She is losing a little weight, no side effects. I have noticed some skin dryness and wrinkles around the neck, a little fatigue, but overall, much better than before treatment. Thanks to the lymphoma clinic in Fred Hutch Cancer Center, Seattle, and thanks to the Beigene company and their support team."

• dmp...
• Taken for less than 1 month
• February 1, 2024

Brukinsa (zanubrutinib) "I started on Brukinsa on the 5th. I marked improvement in my headaches. I was on Imbruvica since March of 21, starting at 420mg and then reduced to 280mg in hopes of reducing headaches. There was no improvement, so I was taken off it totally on November 15th. I still have issues with bad headaches, but the intensity isn't as bad."

• Nic...
• Taken for 1 to 6 months
• June 12, 2024

"Diagnosed in 2013 and had treatment in 2019 with bendamustine-rituximab. I was in remission for nearly 3 and a half years when my CLL returned. I have now completed my first month of zanubrutinib. No side effects so far and noticed that the fatigue I was feeling has significantly lessened."

• Ste...
• Taken for 1 to 6 months
• August 7, 2024

"I started Brukinsa about two months ago after tests revealed that the CLL had invaded my bladder and prostate. My oncologist first started me on Obinutuzumab + Venetoclax, but I had a severe reaction, and she changed my protocol to Brukinsa. To date, I have had no discernible side effects, and I have noticed that my lymph nodes are shrinking. I feel generally good, and my energy level remains high."

• Luc...
• Taken for 1 to 6 months
• November 16, 2024

Brukinsa (zanubrutinib) "Although at last report, white blood cell count went down a little. Having many symptoms worse if cough, runny nose, very nervous, dry mouth, many skin problems arms at times almost black.... tiredness (usually very active), weight gain, swelling of limbs, breasts, etc., top of leg numbness."

• MJB...
• Taken for 1 to 2 years
• November 17, 2024

"White blood cell count reduced dramatically to just under 10, after a brief spike to 200. Only side effect is random small bruises. Maintaining normal lifestyle with good energy. I am very grateful and have a new appreciation for life:)"

• Jan...
• Taken for 1 to 6 months
• December 19, 2024

"Headaches, lower back pain, and I look very pale. I take 80 mg, 1 capsule daily. I have only been on this medicine for a bit over a month, so maybe it is too soon to tell what exactly is happening. I will see my doctor in January 2025 and discuss any problems or lack of at that time. This is a very easy medicine to take, and I hope it turns out to work well for me."

• Ste...
• Taken for less than 1 month
• March 3, 2024

Brukinsa (zanubrutinib) "4 weeks so far so good. No side effects. Lymphs have gone down."

• Bru...
• Taken for 1 to 6 months
• February 3, 2024

Brukinsa (zanubrutinib) "Already 4 months on Brukinsa. All enlarged lymph nodes have disappeared. Very minor side effect - upper right foot skin sensitivity. So far, it has worked very well for me."

• jus...
• Taken for 1 to 6 months
• March 17, 2024

"Bruising. Lethargy. More skin cancer. I think it's working, but I hate it. I've thrown up a few times after taking it. I'm tired all the time and it makes me grumpy."

• Anonymous
• Taken for less than 1 month
• June 3, 2024

Brukinsa (zanubrutinib) "At times, after taking Brukinsa, seem to feel tired."

• Sim...
• Taken for 1 to 6 months
• May 20, 2024

Brukinsa (zanubrutinib) "Rash on face after 1st month; I started to cough out blood after 8 weeks"

• Bru...
• Taken for 6 months to 1 year
• August 23, 2024

"Effective, results were noted within a couple of days. My issue was swelling around the eyes, which progressed over 5 months to a state where I could barely open my eyes."

• Mon...
• Taken for less than 1 month
• November 20, 2024

Brukinsa (zanubrutinib) "I have just started my journey. (Second day on the drug.) I look forward to seeing the results as time moves along. I also look forward to hearing others' comments."