Zanubrutinib and Fatigue: What Users Say

• Vic...
• Taken for 1 to 6 months
• September 26, 2024

Zanubrutinib for Chronic Lymphocytic Leukemia "My mom, 74 years old, started taking Brukinsa recently on Aug 20, 2024. All swelling lymph nodes on the collarbone and underarms are gone. She is losing a little weight, no side effects. I have noticed some skin dryness and wrinkles around the neck, a little fatigue, but overall, much better than before treatment. Thanks to the lymphoma clinic in Fred Hutch Cancer Center, Seattle, and thanks to the Beigene company and their support team."

• Sid...
• Taken for 6 months to 1 year
• June 6, 2024

Zanubrutinib for Waldenström Macroglobulinemia "Was totally fatigued and had severe weight loss. Two weeks on Brukinsa, noticed the difference. Taking 160mg in the morning and 160mg in the evening. After taking these for one year, my weight is back to normal, no serious side effects, did have some bruising at the start. Healed quickly."

• Lar...
• Taken for 1 to 2 years
• November 9, 2024

For Waldenström Macroglobulinemia "Zanubrutinib has handled WM very well for me. All blood test results are within acceptable results. I was initially prescribed 2 capsules in the morning and 2 in the evening. My symptoms improved and I’m now taking 1 capsule morning and evening. Side effects most experienced are general fatigue, occasional constipation, occasional burning urination, and almost always have bruising on my arms and back of my hands."

• Nic...
• Taken for 1 to 6 months
• June 12, 2024

For Chronic Lymphocytic Leukemia "Diagnosed in 2013 and had treatment in 2019 with bendamustine-rituximab. I was in remission for nearly 3 and a half years when my CLL returned. I have now completed my first month of zanubrutinib. No side effects so far and noticed that the fatigue I was feeling has significantly lessened."

• ssg...
• Taken for 1 to 6 months
• December 20, 2022

For Waldenström Macroglobulinemia "My IGM has gone from 2400 to 285 in 3 months after going from 4000 to 2400 doing R-CHOP for 4 months. I feel much, much better than I have for the last 9 months. Some of my problems, I'm blaming the R-CHOP. The only problems I'm having are fatigue and joint pains. This could be my 75th birthday and the R-CHOP, but I really didn't have any real pain in my thumbs until I started on the zanubrutinib. And it seems to get much worse. My hands are very swollen overnight. I'm not able to hold a golf club."

• Gra...
• Taken for 1 to 2 years
• January 11, 2025

Zanubrutinib for Waldenström Macroglobulinemia "My dose is currently 160 mg once per day. I have few side effects. Some muscle and joint issues, which are resolved pretty well by stretching, exercise, and relaxation techniques. It has given me my life back. I was using a walker when first diagnosed with lymphoma. Now I can walk, hike, and bike for an hour. Fatigue is definitely an issue, so I need to rest in between activities. While I can't just take off for a day like I used to, I am still living a good life. It is crazy expensive, but between Medicare, my supplemental insurance, and help from the manufacturer, I haven't had any copay. I'm so grateful."