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Vilazodone for Major Depressive Disorder User Reviews (Page 5)

Brand names: Viibryd

Vilazodone has an average rating of 5.6 out of 10 from a total of 217 reviews for the treatment of Major Depressive Disorder. 45% of reviewers reported a positive experience, while 41% reported a negative experience.

Reviews for Vilazodone

  • RicHM
  • Taken for 2 to 5 years
  • October 4, 2017

Viibryd (vilazodone) "I have been taking Viibryd for years now. It was extremely successful at taking away suicidal depression and and a extreme social anxiety, due to mild aspergers. It also gave me a tremendous amount of energy. After a good amount of time with 40mg a day dose, I started experiencing side effects. The first side effect was upset stomach, with diarrhea. Next I started noticing mental exhaustion, and slight dry mouth. Then the side effects went to severe Temporomandibular joint dysfunction (TMJ) issues, and tension headaches, sometimes accompanied by neck region night sweats. Then my doctor and I decided to cut the Viibryd down to 20 mg a day. I have been on the 20 mg for a while now, the TMJ is gone, all other side effects have been reduced. Over all happy still."

8 / 10
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  • Hannah
  • Taken for 1 to 6 months
  • March 23, 2022

Viibryd (vilazodone) "The side effects I experienced while taking Viibryd overwhelmed the benefits. Six months prior to trying Viibryd I had been on 150mg of Effexor for two years, but its effectiveness plateaued and the GI issues I had, made it no longer a good fit. I started on 10mg of Viibryd for three weeks and initially,I felt more energized, less agitated and slightly more upbeat along with intestinal distress, headaches and insomnia, which I expected for a short period. After three weeks, both the benefits and side effects waned, so I titrated up to 20mg with stronger side effects plus anxiety which started to increase as the medicine started to build up in my system. I had a non-stop headache, ridiculous insomnia and worsening anxiety. I became so exhausted from never sleeping and disappointingly my depressive symptoms did not improve. I stopped taking Viibryd a week ago, but I continue to have insomnia and intestinal discomfort."

3 / 10
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  • jayeb
  • March 2, 2017

Viibryd (vilazodone) "Absolutely horrible experience. I would wake up every night at three having an anxiety attack thinking I was dying. Several nights I experienced the strange vivid dreams. My depression and anxiety increased immensely, and suicidal ideation set in hardcore. BEWARE OF WITHDRAWALS!!!! I have never had so much anger and rage in my life. Even after two weeks still making my depression worse as well as anxiety. DO NOT TAKE THIS DRUG"

1 / 10
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Frequently asked questions

  • DJB
  • Taken for less than 1 month
  • April 18, 2023

Viibryd (vilazodone) "After years of struggling the medical solution was always to increase your current dose and add another medication. Last year I took the Genesight DNA test. I started Viibyrd at 10 mg for the first week and then increased it to 20 mg. It's been a struggle to adapt, I have had episodes of crying, feeling anger, sadness, and a whole gamut of emotions. Surprisingly after 2 weeks, I began to feel its effects and the good continues to build. I have not had any stomach issues as I take daily it with food and a glass of milk. Thank goodness so far no sexual side effects. Finally, I have a medication that my body metabolites correctly. Recommend the Genesight testing for it will help you narrow down which medication works best for you."

7 / 10
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  • DbLH
  • Taken for 6 months to 1 year
  • March 2, 2018

Viibryd (vilazodone) "My update...I have now been on Viibryd for about 5 months. Had anger/ anxiety until I added a low dose of Cymbalta. This has been a perfect combination! I’ve had NO depression/ suicidal thoughts AT ALL which is amazing for me. Have since joined a health club, work out, interested in activities, hobbies. Have even wondered if I could work once again for the first time in 8 years. I still do have a fear of going down hill once again as I have long history of severe depression/ suicides. I pray that I can remain as well as I feel now. Thanks to Viibryd."

8 / 10
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Are you taking this medicine?

  • DbLH
  • Taken for less than 1 month
  • August 10, 2017

Viibryd (vilazodone) "Less than a week ago I reviewed Viibryd. Called my Dr as I am so confused about this med. She says give it a least 6 was. to work, which is ridiculous. This med has SOME good effects, doesn't cause sexual problems, I'm getting a lot done around the house , energetic, excellent concentration BUT I'm a nervous wreck, sleep 2hours at a time, horrible nightmares now about people ganging up on me and I'm swearing at them in anger. Ruined my relationship with adult daughter and she cut me out of her life and my grandchildrens. I'm perfectly fine until I'm NOT, uncontrollable rage, suicidal feelings ( won't act on them I hope) , cry , sob uncontrollably. Sopping wet with sweats/chills during my sleep, nasty to my husband. Stop or stay on???"

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  • Bob
  • December 4, 2018

Viibryd (vilazodone) "I am up to 40mg per day now and something strange is going on. I am feeling waves of electricity zap in my head like mini seizures. I never had a sensation like this before and I have tried many over the past 20 years. I even feel like I might fall down. I even did the genetic testing to see which drugs worked better for specially me. I don't know...but if this is a side effect then how long do I have to endure it?? I think I will go back and try Latuda. It seemed to smooth things out for me. PS. BY THE WAY...YOU ARE SUPPOSED TO TAKE THIS WITH FOOD "

4 / 10
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  • Paducah...
  • Taken for 2 to 5 years
  • April 20, 2016

Viibryd (vilazodone) "This drug probably kept me from killing myself, but missing a dose once after using it for almost two years and I was diagnosed with withdrawal. It hurt. Bad. Worse was getting was even my Psychiatrist called "brain zaps". They started out very infrequent and weak, but as time went on it was torture. They were around the clock and even woke me up every night several times each night. I almost want to leave my email if the drug company wanted to talk to me about it, but can only imagine the emails I would get from everywhere. Best wishes to all."

5 / 10
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  • Ccano
  • Taken for 1 to 6 months
  • December 23, 2019

Viibryd (vilazodone) "Absolutely the worst experience I’ve had with an SSRI and I’ve been taking them for 6 years. Unbearable paranoia, anxiety, and side effects. Heart palpitations, obsessive thoughts, and insomnia. At 10mg I noticed side effects but not as bad, but at 20mg I experienced the worst panic attacks of my life after not having them for months, along with the others listed. I will give this medicine credit for helping my depression, it has done great in that regard. But the anxiety and paranoia has been too much to handle. Telling my doctor to take me off of it tomorrow."

1 / 10
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  • hwhite
  • Taken for 1 to 6 months
  • September 30, 2015

Viibryd (vilazodone) "I started this medication via a sample pack about two months ago. I went up to 20mg. My Doctor thought that I should stay on it longer even though I felt it was doing nothing for me. Now, after two months I have started having lower abdominal pain which turns into discomfort and pain again. My bowels are all over the chart from the diarrhea to very slight constipation. There is no rhyme or reason. I also now have very uncomfortable boating. I have a feeling of fullness in my lower abdomen, and had an ultra sound done by my OBGYN to se if I was having issues with my ovaries or uterus and that came back clean and clear. I also have random nausea. Sometimes early in the day, other times later on at night."

2 / 10
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  • Angel
  • Taken for 2 to 5 years
  • December 27, 2021

Viibryd (vilazodone) "I have been on a total of 10 antidepressants throughout my life. Viibryd is amazing and the only med that really helps me. It keeps me level and my depression at bay. If I miss a pill I am depressed the next day. The 40 MG pill really upset my stomach everyday. So the Dr dropped me down to 20 MG. At one point I was struggling so he told me to take 40 MG until I was better. I took two 20 MG pills did not hurt my stomach. So I'm not sure what the difference is in the pills. If I miss a dose, when I start back I also get a headache and upset stomach for 1 day. It does get rid of my sex drive. I don't even really ever think about it anymore. But the pay off of not struggling mentally is completely worth it. It is SUPER expensive even with insurance. So my Dr sends them a note letting them know I have tried 9 other meds so this one is medically necessary. So insurance pays for it completely."

10 / 10
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  • Confu...
  • September 2, 2019

Viibryd (vilazodone) "Out of desperation I gave this a try.. All I can say is it is awful. I took my first 10 mg and with in 2 hours it hit my intestinal tract. Next day same thing with added headache. Third I decided maybe better to take before bed and I woke up at midnight spent the next 4 hours off and on in the bathroom.. I can't see understand why Dr. Prescribed this.. So disappointed..No way I'm going to take another dose.."

1 / 10
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  • Kill...
  • Taken for 1 to 6 months
  • January 6, 2020

Viibryd (vilazodone) "I was put on viibryd to boost my Wellbutrin and Seroquel as it lost it’s punch. I suffer from PTSD from being raped for 1.5 years straight. This medicine is horrible. I was on 10mg for 7 days then bumped up to 20mg. This medicine gave me the worst cystic acne I have ever experienced in my life. I was unable to climax. I was very forgetful, not remembering one thing from the next. I would consistently be in a daze. I felt no emotion whatsoever. Dreams/nightmares were intense and vivid. The fact alone that I could not climax, was was a huge incentive to discontinue the medication. I weaned myself off of it. I was on it for 6 weeks, and I’m going through intense withdrawal of hot flashes, brain zaps, and nightmares. I still feel like I don’t have the will to live, but having any feeling at all is better than being a zombie."

1 / 10
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  • kano
  • Taken for less than 1 month
  • June 26, 2019

Viibryd (vilazodone) "Well, this is quite the drug. I’ve only been on it for 3 days so far and simply don’t know where to start (I will update my post when I have been on it for longer). I have gone and written way too much so I’m going to see if I can submit this is parts. Part 1: First some background: I am a 36 year-old woman. I have been taking Prozac (gradually up from 10mg to 50mg) for my depression for 3-4 years. It was my miracle drug, and might very well have saved my life. All it did for me was to make me feel normal again, like I used to. It was like Prozac replaced in my brain exactly what was missing and nothing more. Perfect. Almost. The only reason I decided to try another drug is that it had sexual side effects. Zero libido. Sexual feeling diminished. Inability to orgasm. My Doc recommended Viibryd as it has a low incidence of reported sexual side effects. I read hundreds of reviews beforehand that made me very wary, but decided to give it a shot."

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  • Singl...
  • Taken for 6 months to 1 year
  • June 17, 2015

Viibryd (vilazodone) "I think it works amazing, but I have been taking it for almost a year now and I'm starting to gain a lot of water weight!!! I started out at 155 and now I am up to 183! This is huge for me! I'm going to request water pills to take this water weight off"

5 / 10
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  • darlene
  • Taken for 1 to 6 months
  • December 12, 2019

Viibryd (vilazodone) "viibryd was a HORRIBLE experience for me. I was on it for close to 2 months. I had migraines everyday, nausea everyday, hot flashes, cold sweats, and I gained 10 pounds in ONE MONTH. It's been 2 months since I was taken off of it and I'm still trying to rebalance my body from the physical chaos it brought me. Viibryd magnified my symptoms and I was very suicidal to the point where I had to hospitalize myself. I have never experienced as many manic episodes as I had while taking this drug. I'm glad to be off of it."

1 / 10
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  • Really...
  • September 8, 2016

Viibryd (vilazodone) "It help me a little bit but the side effect was so bad, I was having night terror/sleep paralysis. I thought at first I was going crazy or our house was haunted until we moved and realized that it's this medicine, as soon as I stopped, no more night terror. I will never take this medicine ever again. I was so scared to go to sleep for months because of this medicine."

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  • Purif...
  • Taken for less than 1 month
  • August 31, 2015

Viibryd (vilazodone) "I started on 10mg for 7 days and was feeling less reactive and calm. Started 20mg and 3 days in was spiraling into deep depression, agitation, irritability, crying, not sleeping more than 2 hours at a time, shock like sensations down my right arm with my middle finger going completely numb, and headaches in back of head . I already have IBS so I expected GI distress. Nausea for 3 days along with severe diarrhea for about 2 weeks. Diarrhea is intermittent now. I am waiting to hear from my doc about reducing dose to 10mg again. I think that might be my ticket. Good luck to all!!"

5 / 10
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  • alice...
  • Taken for less than 1 month
  • February 6, 2019

Viibryd (vilazodone) "Absolutely dreadful I’ve been taking it for several days and my anxiety is ten times worse, my depression is no better, and I can barely function. I’m breaking down daily, have this awful feeling everyone is out to get me, and my terrible doctor had the nerve to say I should continue it to see how it goes. My insurance wouldn’t even cover this FDA-approved bath salt pills so that should’ve been my first clue it wasn’t worth my time. The medication and her are getting tossed out."

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  • Bird...
  • May 30, 2017

Viibryd (vilazodone) "Been on a plethora of antidepressants most of my life. This one by far has been the worst. I had all of the negative side effects pretty intensely. Insomnia, vomiting, diarrhea, severe headaches, severe agitation, visual hallucinations, feeling like I was crawling out of my skin, sweats, and psychosis so bad to the point, I blacked out and attacked my best friend physically. Thanks be to God my friend was there and I'm not in jail! Just based on my personal experience I think this drug needs to be tested out more thoroughly. I felt like a wretched guinea pig on it. I stopped the drug a few days ago...going through the horrible withdrawals now. The "bath salts" of antidepressants!!!!!"

1 / 10
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  • Mich...
  • Taken for 2 to 5 years
  • September 21, 2021

Viibryd (vilazodone) "Two years ago I was going through a really difficult time. I was too depressed to get out of bed and I felt like I couldn’t get a full breath. A friend told me about her doctor and the “magic pill”, obviously I wasn’t believing that there was such a thing but I made an appointment anyway, it couldn’t get any worse! At my appointment the doctor gave me trial pack that contained 10 mg and 25 mg, she said to start at 10 and then take the 25. I asked what they were and was told antidepressants. My heart hit the floor and I felt like I was going to cry. Over my life I had tried several types of antidepressants that only made me feel worse. I left my appointment and just forgot about the pills. One day about a week later I was feeling so bad that I decided to try half of a 10mg. Within 30-40 minutes I started feeling better, a lot better!!! Long story short It saved my life. I haven’t had real depression since that day, for me it was a magic pill!!"

10 / 10
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  • Anonymous
  • Taken for less than 1 month
  • June 1, 2015

Viibryd (vilazodone) "Traumatic experience caused me to suffer major depressive disorder. Tried therapy, didn't work. Finally tried medication two years later. Doctor prescribed me viibryd. Took my first dose in the morning, by lunch time I felt sick and nauseated. Had to leave work bc I felt so awful. My doctor lowered my dose and I didn't feel nearly as bad the next four weeks. I didn't notice a change in my mood. I went on vacation and forgot to pack my meds (I know how horrible it is to stop taking my meds) the come down was un real... I spent the whole vacation in bed too tired to leave.. When I arrived home from vacation I took my meds again and I was instantly sick. I began hallucinating and puking, it felt like a bad acid trip."

1 / 10
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  • Moria...
  • September 19, 2015

Viibryd (vilazodone) "I'm 16 years old and I hav been on several anxiety/depression medications including prozac, zoloft, lexapro, propranolol, klonpin,etc I take 40mg once a day and this is the first medication that actually works for me. All of the other ones made me suicidal or more depressed. I can defintely tell when I miss a dose of viibryd I get sad and very emotional. I've been taking viibryd for about 8 months. I have gained 15 pounds but I don't know if that is because of the medicine or not. It really bothers me though. i have less of an appetite and sleep way too much, sometimes 4 naps a day. I fall asleep during school I'm super emotional I easily get annoyed, sad, angry. I cry alot . I have no idea if any of these are side effects of the meds or not"

7 / 10
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  • tina...
  • Taken for less than 1 month
  • August 5, 2016

Viibryd (vilazodone) "This is an awful medication. Horrible diarrhea. Horrible crazy off the wall nightmares. Can't tell whats real and what isn't. I saw my mom and she's been gone for five years.. This pill makes me feel like I'm on speed. Crazy speed. I've never in my life felt so bad, and so scared. "

1 / 10
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  • Anonymous
  • Taken for less than 1 month
  • November 9, 2019

Viibryd (vilazodone) "Started Viibryd October 3, 2019 - 10mg discontinuing Zoloft concurrently. No effect on depression but, due to discontinuation of Zoloft decrease in tinnitus and general spacey feelings. October 19, 2019 increased Viibryd to 20mg with scheduled increase to 40mg due November 2nd, 2019. By November 1, 2019 increased agitation, suicidal thoughts with aggressive thinking. After consultation with psychiatrist it was recommended I discontinue immediately with a recommendation of inpatient hospitalization. Six days of inpatient and totally off of Viibryd I feel much more in control and more myself. Genetic testing indicated that this medication should have a good match. This stuff is poison."

1 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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