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Vilazodone for Major Depressive Disorder User Reviews (Page 4)

Brand names: Viibryd

Vilazodone has an average rating of 5.6 out of 10 from a total of 217 reviews for the treatment of Major Depressive Disorder. 45% of reviewers reported a positive experience, while 41% reported a negative experience.

Reviews for Vilazodone

  • BouvMom
  • Taken for 2 to 5 years
  • October 4, 2016

Viibryd (vilazodone) "I tried to go off this drug after undergoing TMS treatment, but I could not. It is as addictive as heroin. I needed to go onto Wellbutrin and Prozac to bridge over and taper off the Viibryd over a period of several weeks and the withdrawal syptoms were awful."

4 / 10
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  • Anony...
  • February 15, 2017

Viibryd (vilazodone) "I've used Viibryd for a couple of years. 40 mg grew to being jittery, even with exercise. At 20 mg I have improvement. I'm much more functional. Being lactose intolerant, it's not uncommon to have diarrhea from time to time. If early in the day, it seems to cause a drop in energy, focus, etc. As needed, I sometimes take an additional 10 mg at lunch. Previous medicines tried were Prozac and Cymbalta."

10 / 10
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  • donha...
  • July 4, 2014

Viibryd (vilazodone) "The first few weeks it seemed to improve my depression. I almost felt normal again. Then Wham! I started crying about everything---happy, sad,or for no reason at all, and although the feelings of "hopelessness" were gone, I felt I was worse than before. I have been diagnosed with early-mid AD and perhaps that explains the odd reaction.I haven't seen my doctor since this odd reaction began, but intend to see him. I have also suffered severe gastric distress while on Viibryd."

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Frequently asked questions

  • Sleep...
  • Taken for 1 to 6 months
  • August 4, 2019

Viibryd (vilazodone) "So far-great,considering prior to trying this med, l was staying in bed all day and would have stayed all night if I didn’t have a husband who nagged to get me up! Viibryd is the only change along with also adding Abilfy. Though my doctor did also start Lunesta at the same time, since my brain would not shut off and let me sleep! The drug cocktail is working for me quit well! It’s nice to see the day and actually want to get out of bed, hoping things stay this way. Although my issues in life still remain I am able to handle them a lot better! Just so the meds stay on track and I don’t get any crazy side effects that’s my only concern."

9 / 10
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  • bborc...
  • Taken for 1 to 2 years
  • February 20, 2024

Viibryd (vilazodone) "I have been on and off other antidepressants all my life. Some worked, some did not; some made me feel horrible (most of them did). I am really sensitive to side effects. This drug has been awesome for me. I noticed some changes very quickly. I had no side effects at all; I do take it with food. Overall, I really like this drug. It has really helped me to feel somewhat normal. I am a little worried as it doesn't seem to be working as well lately, but I am going to see about going up in dose. I am at 40 mg a day."

8 / 10
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Are you taking this medicine?

  • Yaya
  • September 6, 2015

Viibryd (vilazodone) "I have been on lexapro and abilify for several years. The combination of the both were not helping. When I started taking viibryd I had your typical side effects but they went away and I have been on it three months and have felt better then ever. The only problem I have had is nightmares when I accidentally miss a dose ..anybody else have that?"

9 / 10
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  • Alive
  • January 14, 2018

Viibryd (vilazodone) "Saved my life. After being on Effexor XL 300 mg per day for 7 years and it was stopped abruptly due to tachycardia and increased depression, my physician started Viibryd. The withdrawals from Effexor were horrific. It took many weeks to withdrawal (and I believe I still am having some long term side effects even after 2 years) and many meds before Viibryd was started. I now take Viibryd 40mg at night and 20 in the morning along with a probiotic that has helped The expense of the Name brand only med right now, is worth every penny because you cant put a price on your life. I am alive and mentally better than I have been in 10 years. Thank you"

10 / 10
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  • RAano
  • Taken for 1 to 6 months
  • May 30, 2019

Viibryd (vilazodone) "Been on Viibryd for about 6 months now. Works great for me, no depression symptoms at all. I have noticed that it is difficult for me to get excited about anything though...it sort of makes me just numb to all emotions, which helps with anxiety and social phobia. Side effects of diarrhea and gas were terrible, but the pros outweighed the cons in my case. After 6 months I still have occasional diarrhea. Very vivid dreams at night, and every night. Expensive."

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  • DKMDD
  • August 28, 2015

Viibryd (vilazodone) "For first week on 10mg, had brain zaps, diarrhea, tingling on extremities, and some nausea, insomnia. Almost discontinued taking drug. However, after a week, most side effects improved, Now on 20mg per MD recommendation, only have insomnia and some leg cramps now, slight weight gain but not much. Mood improved and bonus is that my sexual function has improved for the first time in 10 years. Based on my experience so far, would recommend if you are willing to tolerate side effects for several weeks when beginning drug."

8 / 10
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  • Salsb...
  • June 4, 2015

Viibryd (vilazodone) "I started taking this medication a month ago. My doctor had been prescribing me Xanax for 10 years and felt this was the cure for my anxiety. I experienced worsening anxiety and panic attacks. I felt really irritable and still do. By the 5th week I was beginning to feel hopeless and not wanting to get out of bed. I'm always tired, and I have gained 10 lbs in 5 weeks. I'm supposed to take it for another month and if it still doesn't help then I get to taper off. I accidentally missed a dose and felt miserable. I had no energy, and felt like electric shocks were popping my brain cells. I still have anxiety and feel like this medication gave me depression."

2 / 10
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  • Dom
  • Taken for 2 to 5 years
  • October 2, 2019

Viibryd (vilazodone) "Since I was 14 I took about 10 meds a day for bi polar boarderline personality disorder ptsd major depression and anxiety. Now I thankfully only take viibryd and it's saved my life! The only sorta bad side effects I have is if I take it before I eat breakfast I become extremely tired to the point if knocking out. If I miss a dose my face gets extremely itchy. But other then that I'm doing great I still have some bad days but not nearly as bad as before!"

10 / 10
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  • clare
  • January 24, 2020

Viibryd (vilazodone) "10 MG Viibryd for 1 month, 20MG for 1 week. Everything fine, slightly lightheaded. 3rd day on 40mg my left pupil dilated & would not contract. 4th day on 40 mg: lilliputian hallucinations, visual and auditory hallucinations began of evil beings threatening to kill me upon waking at 3 AM. Did not know where I was. Mouth was just opening and closing mouthing gibberish was told later. Xanax calmed me down. Hallucinations began again every time I would try to sleep. Body would try to jolt itself awake. When able to finally sleep, would be for only 1 hour and be vivid nightmares about death. Psychotic thoughts and itching about my skin and eye skin and thinking that my hair needing to be removed because of an evil bug implanted in them by the hallucination characters. NEVER had psychotic thoughts in my whole life. This has all been going for 2 and 1/2 days. I've tried 20 different SSRIs/SnRIs, two TCAS, Abilify, Seroquel, this is the worst reaction I've ever had."

1 / 10
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  • Steven
  • Taken for 5 to 10 years
  • December 9, 2022

Viibryd (vilazodone) "Viibryd replaced Cymbalta for me. Almost all other antidepressants had bad side effects. Viibryd did not have side effects and helped with depression. I no longer have "bad thoughts," and it helps keep me stable. I cannot say enough about how great it helps."

10 / 10
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  • VonnieB
  • Taken for 2 to 5 years
  • February 22, 2016

Viibryd (vilazodone) "Suicidal early 20s-previous control found with counseling, Zoloft, Effexor, no other drugs giving much or lengthy control of disease. About 2 yrs ago began Viibryd-quickly brought up to 40 mg dose. Still have dry mouth and some diarrhea (so bad at first it actually turned into IBS for me) and continue with daily headaches and queasiness, though no weight gain as others reported. Last 5-6 months have noticed sharp increase in sudden unexpected crying with no ability to stop, and now more aggressive feelings and an increase in suicidal ideation which I have not had for many years. Very surprising and frightening after all this time (40 years since diagnosis). Will wean off this drug soon when/if I can find a Dr to address these issues"

8 / 10
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  • take...
  • June 23, 2017

Viibryd (vilazodone) "I'm a health care professional myself and was prescribed Viibryd for depression and anxiety. This medication is by far the worst medication I've taken. I started taking the recommended dosage with the starter pack. I experienced all the side effects ( nausea, diarrhea, vivid dreams, zaps to the brain). The worst is I ended up in the ER with a panic attack and these panic attacks have continued. Of course I'm off this medication immediately recommended by the ER physician and my personal MD. There are too many negative personal experiences with this medication. Even though everyone reacts differently, there is a correlation."

1 / 10
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  • taysh...
  • October 2, 2018

Viibryd (vilazodone) "I was first prescribed Trintellix and it was the worst medication too much nauseous and vomiting. Then I started Viibryd and is the best ever no side effect at all, no gain weight. The only bad thing is really bad insomnia however my depression is better thanks for viiibryd. With coupon I pay $10.00!"

10 / 10
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  • Unnamed
  • December 3, 2016

Viibryd (vilazodone) "I started taking this medication for major depression and anxiety. The first month was great I was sleeping well and I was very happy and wasn't stressed then it all turned. I began to have vivid nightmares that I woke crying and screaming. I started having trouble staying asleep not just from the nightmares but I couldn't bring myself to sleep. I stopped taking the meds and talked to my psychiatrist about my concerns I told her I didn't take the meds everyday at the same time so she told me to try it again. I started a strick time regimen. I started having dizzy spells, started hallucinating, nightmares again, I would get weak and Shakey. I took sleep meds still no sleep. I still had depression. It was horrible."

1 / 10
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  • Kprat...
  • April 23, 2016

Viibryd (vilazodone) "Viibryd has changed my life I was so lost I had actually forgotten how it felt to smile and laugh . My only issue is due several injuries I have suffered and the cost of my doctor visits and other medications that I am taking it has been quite a financial hardship I wish this medication was lower priced ."

10 / 10
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  • Shelly...
  • September 16, 2017

Viibryd (vilazodone) "I have been on & off antidepresants most my adult life & have tried many. Was just switched from celexa to viibryd about 1 month ago & it has been a living nightmare. This has by far been the worst med I have ever been on. I have been an emotional wreck & sick as hell. Nausea, dizzy, shaky, jittery, heart racing, weight gain, headaches, anger, crying & several more. I have actually had to pull my car off the road & sit because I was so sick. I can't think straight at all. Tried tapering down from 20mg to 15mg for a week & I felt like I was dying, so went back to 20mg. I feel like I belong in the mental ward. I see my Dr in a few days. Horrible drug, I do not recommend at all! Rather be depressed"

1 / 10
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  • Athol...
  • Taken for 1 to 6 months
  • July 28, 2017

Viibryd (vilazodone) "I started taking this a little over a week ago. I tapered off of Zoloft , and started with 5.mg of the vibryd, and then up to 10mg a day about ten days ago. I can honestly say that I'm pretty sureI feel out of control , and cry at the same time. I'm filled with utter contempt , and rage at everyone and anyone in my vicinity. I'm not a rage filled person. I want to cry at the same time. I'm just plain angry all the time. My depression has worsened, and the rage and crying is all the time. My doc is not available , so I contacted the pharmacist, and said to continue to take the vibyrd as directed and go to the ER if it continues , or gets worse. Well I'm not waiting. I've taken myself off of it starting today."

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  • Srolen
  • Taken for 1 to 6 months
  • August 14, 2017

Viibryd (vilazodone) "I've tried numerous anti depressants with varying degrees of success and failures. I transitioned to Viibryd from Trentellix. I started out on 10mgs per day and titrated up to 40 mgs. Within the first week my mood and demeanor became more positive. I stopped thinking about suicide. I did experience some side effects such as vivid nightmares and the inability to sleep. Major trouble sleeping at anytime. I told my doctor and she added Zyprexa 10mgs at night. Finally I could sleep. I'm going to see if she'll increase it a little more. This combination works wonders for me. If Viibryd alone isn't working for you try adding an anti psychotic or mood stabilizer. I feel really good on both of these medications. Finally, something worked."

8 / 10
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  • Mom2t...
  • June 16, 2017

Viibryd (vilazodone) "Truly the worst medication I have ever been on.. I had all of the bad side effect diarrhea in the middle of the night had to change the sheets, nightmares so bad that I slept with the lights on, brain zaps, migraines still to this day even after being off of this medication for 2.5 years. Dizzy spells, Black outs, I couldn't even drive while taking this. I'm sure there is more. I weaned myself off of this medication against my Doctors orders because he was convinced that this was a miracle drug needless to say he is no longer my Doc."

1 / 10
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  • Mags
  • September 26, 2019

Viibryd (vilazodone) "Taking this medication was one of the worst experiences of my life. Depression got worse, but I figured it was a side effect that would go away over time. One night, all of a sudden the whole room felt like it turned upside down. Other people have referred to this as "head drops" and that's the only way I can describe it. I starting getting horrible nightmares and had sleep paralysis for the first time in my life and it was terrifying. At night, I would hear loud explosions in my head. I would wake up and be unable to go back to sleep because the sleep paralysis was too scary and I started becoming extremely paranoid, like something was going to come kill me. Driving home from work at night I would hallucinate people darting in the road or hanging from the trees. It was very difficult to distinguish between reality and dream/hallucination. I weaned off the meds and everything went back to normal within a few weeks. What could happen in side effects isn't worth what good it could be."

1 / 10
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  • kimmyg
  • Taken for 1 to 6 months
  • December 10, 2016

Viibryd (vilazodone) "This medication is terrrible. Right away I was experiencing nausea every day. I had blurred vision and I felt like I couldn't think very well. My brain was all foggy. I craved sweets and carbs all the time. I took it for a month and gained about 15 pounds. I also had the most extreme horrible vivid nightmares where I was afraid to close my eyes and sometimes I felt like I couldn't wake up. I woke up covered in sweat with a racing heart frightened. I also got brain zaps where it felt like my brain was being electrocuted for a second I feel like I turned into a monster on this drug. I was filled with so much rage and anger and I hated everyone and everything. I would have times that I just broke down crying uncontrollably. So i switched"

1 / 10
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  • Sick
  • Taken for 1 to 6 months
  • May 22, 2019

Viibryd (vilazodone) "On Viibryd I had stomach cramps, insomnia, angry outbursts. I have taken every pill there is for MDD I think. This is the first to help me get out of bed. But, makes me nervous and sick. I wake up every hour or two. I wished the side effects were not this bad. I can't continue taking this medicine, plus it costs me $135.00."

4 / 10
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15 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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