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Vilazodone for Major Depressive Disorder User Reviews (Page 3)

Brand names: Viibryd

Vilazodone has an average rating of 5.6 out of 10 from a total of 217 reviews for the treatment of Major Depressive Disorder. 45% of reviewers reported a positive experience, while 41% reported a negative experience.

Reviews for Vilazodone

  • Anonymous
  • Taken for 1 to 6 months
  • July 17, 2014

Viibryd (vilazodone) "I have struggled with depression as long as I can remember. I was first started with Zoloft. It worked for 3 months. I felt great! Then it stopped working. Same exact thing with Viibryd. It's supposed to be fabulous and better than all other antidepressants. I've read reviews on how it's tremendously helped people. It just hasn't helped me. I felt a difference while taking the medication and again it stopped. I spiraled back into my depression. I'm currently trying different treatments and apparently I was misdiagnosed. I am bipolar."

4 / 10
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  • Kell
  • Taken for 1 to 6 months
  • February 17, 2016

Viibryd (vilazodone) "I was prescribed this after a nervous breakdown while an inpatient at the hospital. I have zero side effects, well perhaps I'm a bit more "flighty". It does not numb me like other meds have done in the past. I feel like I'm living my life again and enjoying my loved ones. I'm on 20 mg I hope the doctor will increase to 30 because I feel near the finish line but not 100% there yet."

9 / 10
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38 Report
  • KalRock
  • Taken for 1 to 2 years
  • December 1, 2014

Viibryd (vilazodone) "Viibryd has worked extremely well for me. I haven't taken any other antidepressants in the past. One of my main concerns was the loss of sexual arousal. I'm in my early 20s and that scared me a little. I was informed Viibryd doesn't reduce your sexual arousal as much as others do. My Psychiatrist did tell me this medicine is more expensive than other anti depressants right off the bat, even with my parents insurance plan. I'd say one side effect of this medicine for me is that I need to take it every day. I notice a crash effect if I miss a day or take it later than I usually do in the morning. For some reason the 30MG tablets were more expensive than the 40MG tablets."

10 / 10
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42 Report

Frequently asked questions

  • Brooke
  • Taken for 1 to 6 months
  • October 30, 2014

Viibryd (vilazodone) "This medication literally saved my life. I noticed a difference after a few days on 10mg. I had diarrhea once. I did have a TON of gas for a few weeks. I also have been eating a high protein diet since starting this medicine. I am not sure if that helps. Have been on 20mg for about 3 months. Only side effects I have are mild RLS and I wake up after 4 hours. I take 1000mg L-tryptophan at night and I sleep just fine now. 30mg would work better for me as far as the depression goes (unfortunately, that is not manufactured), but I can't afford two prescriptions. 20mg also seems to make me manic when I am PMSing, but the depression was so bad that the benefits outweigh the risk, so I am staying here. 40mg would make me a basket case."

10 / 10
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40 Report
  • Dakoda
  • Taken for less than 1 month
  • June 9, 2019

Viibryd (vilazodone) "I took the gene test and was prescribed this medication, I couldn't adjust to it and it felt like my brain was on fire and my anxiety was increased and physically I felt so horrible. I also ended up lashing out at my therapist and we are on bad terms as a result and the cops were called on me. For me this medication was not suitable and I want to advise people to just be careful. Kuddos if this actually works for you."

1 / 10
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Are you taking this medicine?

  • Anonymous
  • Taken for 1 to 6 months
  • June 15, 2016

Viibryd (vilazodone) "30 y/o female struggling with OCD/MDD/GAD since 14yo. The pack I received started 1wk at 10mg, then 1wk at 20 mg then the next 2wk at 40mg. The second week I was actually feeling hopeful that I may have found a medication that works for me again. Things quickly changed once I started the 40mg dose. I wake up in a stupor like fog that takes me about an hour to get out of. My dreams are so vivid and intense that I have difficulty shaking from them. I am now experiencing sexual side effects, dizziness, and very bad leg cramping. I almost got into an accident this morning because of the fog that I was in. Ironically I was going to pick up this medication. Returning to 20mg dose until I can see MD again. Seemed to work at low dose, now scary."

4 / 10
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  • Kandiey
  • August 16, 2016

Viibryd (vilazodone) "I have suffered from major depression since my 20's, I am now 50, I have taken every antidepressant I think possible, since I have started taking Viibryd I feel human, I have more mind clarity,energy and generalized feeling of happiness. I laugh and talk a lot more! I feel like someone turned the positive switch on in my brain, it's like the sky is bluer, trees are greener, etc! I started taking this medicine after my sister told me she had started taking it and how wonderful she was feeling. I have had absolutely no side effects except eating more but that could be because I have an appetite now.I am taking 20mg right now and have been taking it for several months. I feel like this is a miracle drug and is exactly what I have always neede"

10 / 10
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33 Report
  • Ashley
  • Taken for less than 1 month
  • September 20, 2021

Viibryd (vilazodone) "I have NEVER in my entire existence ever thought I'd be here writing this review but here I am. I'm 28 years old, female whom has struggled her entire life with my emotions and moods. I have borderline personality disorder, major depressive disorder, PTSD, I have tried so many antidepressants over my lifetime that I actually assumed I was broken because nothing worked for me. You name it I have tried it. I was watching tiktok one day when a video explaining this medication came on and from that moment forward I knew this medication was for me. So I called my doctor and asked her if it was possible for me to try it (it is very expensive) she called it in and medicaid approved it (only because we have tried all other SSRIS and they didn't work). Let me tell you guys... MY LIFE HAS CHANGED!! THIS DRUG HAS LITERALLY SAVED MY LIFE!! Please try it ♡"

10 / 10
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  • Kavel...
  • Taken for 1 to 6 months
  • February 13, 2017

Viibryd (vilazodone) "I was on Cymbalta before this and made me numb. Took this starting at 10mg and on 40 mg now. Been taking since Dec, so two months now. Hard on stomach at first, running to the bathroom. This med like lifted the fog from my outlook. I mean like I actually feel good like I never have. Able to talk to people and initiate conversation whereas before I would give monotone answers to questions. I think clearer and my memory is better. This is a miracle for me. Not really any sexual side effects and I am male. I had bad sexual side effects with Cymbalta. I take it in the morning with breakfast and I find it goes in my body better with protein like eggs or sausage. It has the effect of energizing me. Pricey after insurance without the coupon card."

10 / 10
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31 Report
  • Mother...
  • Taken for 1 to 6 months
  • February 22, 2020

Viibryd (vilazodone) "My older sister is a psychiatrist and my younger sister is on this med. They both suggested I try it because it worked so well. I finally gave in and gave it a go around Christmas. It was the worst thing ever for me. I gained 11 pounds in 7 weeks, I couldn't stop crying, I didn't care about anything anymore. I almost checked into a Psych ward. Coming off of it was tough but definitely better than staying on it. I've been on a new med for a few weeks and I'm feeling so much better."

1 / 10
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21 Report
  • Apple...
  • Taken for 1 to 2 years
  • March 10, 2022

Viibryd (vilazodone) "I have taken so many different anti-depressants and all of them either did not work or made me feel worse. Not Viibryd! I feel amazing on this medication, a life I've always wanted to live feels possible because of it. I've been on it for almost 2 years now and cannot tell you the turn around in my life. From suicidal and hopeless and now I am happy, motivated, and positive. I hope to what ever higher power exists that it never stops working for me and I can always afford it."

10 / 10
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  • Hilsk...
  • Taken for less than 1 month
  • July 24, 2015

Viibryd (vilazodone) "I started viibryd just yesterday on a starter pack from my doctor that I requested. I've tried SEVERAL different antidepressants since I was a teenager: Paxil, Zoloft, cymbalta, celexa, lexapro, and the list goes on. So this brings me to viibryd. I would strongly advise you be very careful with this one. It has strongly resembled an amphetamine for me. I'm on a 10 mg dose and already I woke up an hour and 15 min earlier this morning(1 day) I felt very alert throughout the entire day at work, and even still feel so wired I can't imagine going to sleep for several more hours(it's 10:30 pm). I'm not sure about titrating to 20mg with this current effect. I'll see how it goes and keep you all updated! Any reaction from others would be helpful!"

7 / 10
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  • Anony...
  • Taken for 1 to 6 months
  • December 8, 2020

Viibryd (vilazodone) "I've taken antidepressants for 30 years. Over time, even the best ones lose effectiveness for me. I've recently been described as "medication resistant". I recently took Viibryd for 10 weeks. It was a pure nighmare . My side effects included debilitating nausea, diarrhea, increased and immobilizing anxiety, increased depression, suicidal thoughts, generalized weakness, inability to focus, memory loss. I spent days either in bed or on the couch. I was completely nonfunctional. I didn't even realize how bad things were until I weaned off of it. I lost 20 pounds in three months from an inability to eat. After 2 weeks completely off of Viibryd, anxiety is almost completely gone. This experience is nothing like anything I've ever had on any antidepressant before. It was severely debilitating. Never again."

1 / 10
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  • Kendall
  • Taken for less than 1 month
  • May 4, 2020

Viibryd (vilazodone) "I was going through a really hard time in life and I had never taken any sort of medication before. My doctor prescribed me this. And I was so super nervous to take it at first reading all of the reviews. But everyone told me just to give it a try. I took it and at first everything was fine, but then I started having a “high” sensation. My heart was racing really fast and I started talking really fast. It felt really weird but I was like “I can get used to this” I went to bed and woke up at 2 in the morning with the feeling of nausea. I finally ran to the bathroom and started puking blood believe it or not. I was panicked. And then I had diarrhea all day as well. I’m assuming I had an allergic reaction to it. Because that was the first night on it. But it was awful. I felt so so sick. So I didn't think this happens to everyone. But I didn’t take it again. A few months later I started taking lexapro and Xanax and I’ve liked that so so so much better!"

1 / 10
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  • Keebles
  • August 12, 2015

Viibryd (vilazodone) "Viibryd is pretty great. It is strong yet subtle. I've tried every antidepressant (SSRI/SNRI/SSNRI) and it is the only one that works well for me. I am having virtually no side effects except for tiredness but it has been getting better. I had diarrhea for the first weak but it was tolerable. It doesn't dull my emotions. It makes me feel normal and stable! Great medication for me and the only SSRI type medication that works. Maybe this has to do with it being a partial serotonin agonist as well as being a serontin reuptake inhibitor."

10 / 10
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33 Report
  • Lorra...
  • March 26, 2017

Viibryd (vilazodone) "I'm the mom of a 22 year old female that LOVES what Viibryd has done for her. Wow and wow. She was nauseous for about a week but as long as you take with food it, your body gets used to it. I will happily make a commercial for Viibryd for what it has done for our daughter. Of course, I don't know how long this will last, but for now I am forever grateful. We took her off Prozac last October because it had run its coarse for 3 years. For the past year she has been suicidal, anxiety, you name it. She started Viibryd 3 months ago. She is getting straight A's in all 5 classes at FSU this semester, where last semester she flunked all her classes due to not being able to leave the house due to panic attacks. I'm so happy to have my daughter back."

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  • Spikes...
  • Taken for 2 to 5 years
  • March 17, 2016

Viibryd (vilazodone) "My dr. had me on Wellbrutrin for several years without much improvement and I gained a ton of weight. She changed me to Viibryd about three years ago. It helps with most of my depression. It takes the edge off, except when my depression is really high. I have no noticed many side effects. I do not feel like a zombi while taking Viibryd. My dr sometimes tries to change my meds but we always go back to Viibryd. Still have suicidal thoughts but not as much and I can handle them for the most part. I have not gained weight with Viibryd. I hope to stay on Viibryd, unless my condition becomes worse. I am at the top mg (40 mg)."

8 / 10
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  • Menta...
  • Taken for less than 1 month
  • November 15, 2016

Viibryd (vilazodone) "I started viibryd for anxiety disorders, major depressive disorder and paranoia. I have been taking it for 9 days (the starter pack). Now on 20 mg. It seems to be working great for my depression, paranoia and I don't get irritated like I used to. My outlook on life has changed dramatically. Happier and still able to achieve orgasm, unlike other antidepressants. I take Ativan at night for sleep and anxiety, so I have not had any nightmares. The only downfall with viibryd is my back and neck are very tense and achey. Diarrhea first few days but it goes away. Has anybody else experienced muscle aches/tension? If so please let me know."

9 / 10
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29 Report
  • Doc
  • Taken for 6 months to 1 year
  • November 29, 2019

Viibryd (vilazodone) "I have been on Viibryd for about 1.5 years and find that this works very well for me. I lost about 15 pounds since going on Viibryd. I was on Trintellix for about 2 years and it stopped working as well as it did over the duration of taking it. Viibryd is one of the best antidepressants I have taken. I took Celexa for about 4 years and it worked well, but started to lose its punch. I was on Rexulti for about 8 months and took myself off of it cold turkey. I had a few withdrawal symptoms but nothing I could not handle. I give Viibryd a 9.5 out of 10"

9 / 10
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  • nicknr
  • Taken for 1 to 2 years
  • December 20, 2016

Viibryd (vilazodone) "Wow. This medication really works with very few or no side effects for me. I finally feel normal. I am balanced, have appropriate emotions and healthy relationships. After being on Lexapro for a year and experiencing every side effect, Viibryd is a miracle to me. I used to feel numb, flat, disinterested, boring, no sex drive, etc. while on Lexapro. I talked to my doctor about Viibryd and I feel like I'm back to my normal self. I'm on 40 mg. Just remember to take it every day at the same time and never run out. I ran out for a few days while traveling, and the withdrawal symptoms start to kick in after the second or third missed dose, and I felt terribly hungover, cranky, tired and dizzy. Highly reccomend talking to your doctor about Viibryd"

9 / 10
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  • Anonymous
  • March 3, 2015

Viibryd (vilazodone) "I have bipolar, depression, anxiety, and I have been to mental hospitals with suicidal tendencies. I have tried many other medications, and have been on just viibryd for the last year now. Nothing in the past has helped me as much as viibryd has. I went from having anxiety and bipolar episodes to being able to control my outbursts. For people who say they take this medication and it does nothing I believe they may have not taken it long enough. Only adverse effects I have is diarrhea and if I miss a dose by a day I go thru withdrawals pretty bad. I reccomend this medication to every young adult I know!"

10 / 10
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  • Chris
  • Taken for less than 1 month
  • October 1, 2018

Viibryd (vilazodone) "I spoke too soon. This is the worst medication I have EVER taken. For 8 days straight, 24 hours a day with out any break I have been non stop nauseous to the point my face turns pale white, horrifying nightmares, sleep paralysis, no appetite, vision black out with “zaps” or “pressure “ feeling in my head. Extremely high blood pressure, with pressure behind my eyes which concerns me about angle closures with it said in the med pamphlet can cause glaucoma. Which causes blindness. Difficulty understanding, hot and cold, flu like symptoms, weakness, anger/rage, uncontrollable crying, blurred vision, pain through out body, excruciating painful burning sensation in my stomach always. Seeing things that are not there... these have been symptoms I’ve experienced every day and night with no break for 8 days. Almost went to ER several times, I weaned myself off this med. This is poison to my body. I was so hopeful for this medication too."

1 / 10
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  • Solo
  • Taken for less than 1 month
  • December 19, 2018

Viibryd (vilazodone) "Viibryd is working great for depression and anxiety! Physically I’m having bad trouble with diarrhea and stomach aches. I’ve only been on it a week so I’m hoping these physical symptoms will diminish. I will put up with these physical symptoms hopefully for a long time because viibryd is so effective . Has anyone experienced this?"

10 / 10
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  • Lovem...
  • Taken for less than 1 month
  • November 8, 2019

Viibryd (vilazodone) "I have tried many antidepressants. Even many mood stabilizers to see if they would help me. Nothing seems to work for me. I had a really bad experience with Viibryd. I only took 10 mg for 2 weeks, but it made me feel really bad. It seemed to awaken some part of my nervous system. It made me feel so depressed and panicky. The fear is out of control, to the extent it's crippled my life. I haven't taken this medication for maybe 3 weeks now, and that scary Viibryd feeling is still there. Usually, when I try a new med within a week after coming off of it I feel fine. Honestly, I'm worried this medication may have permanently keyed up some part of my brain into fear, possibly forever?? Keep in mind I took this for major depression. I have no history of anxiety, fear, paranoia or anything. With the damage this med has done to my brain, I want to warn others. I know I was willing to try anything to feel better, I didn't think anything could get worse, but Viibryd made it worse."

1 / 10
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  • Bashan
  • Taken for 1 to 6 months
  • August 27, 2015

Viibryd (vilazodone) "Positive response within a week. 20mg was sufficient during the spring and summer seasons. Sexual side effects are minimal and virtually disappear once used to the medication after the last dose increase. Insomnia at first, but with time this side effect has gone away. Very satisfied."

10 / 10
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31 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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