Mounjaro and Diarrhea: What Users Say

• Mis...
• Taken for less than 1 month
• September 13, 2022

For Type 2 Diabetes "I usually don’t share reviews but felt this was warranted. I took my first 2.5 mg shot on 9/4, felt fine until 9/7 when the terrible sulfur burps started followed by sour stomach and nausea. Around 10 pm that night, I began 5 days of severe vomiting and diarrhea, which culminated yesterday at the ER getting fluids, CT scans, and IV nausea meds. I will not be taking this shot again. I have not thrown up anymore, but the diarrhea will just not stop. I can’t eat or take any of my other medication properly. Beware. When something sounds too good to be true, it usually is. I’m a past user of Byetta, Victoza, Ozempic, Trulicity, Rybelsus, Bydureon, all the pills, and about every homeopathic treatment ever made. I didn’t take this shot like a blind fool, but I have never had a side effect as terrible as this one. I’ll stick with my insulin. At least I can function like a normal human being!"

• cla...
• Taken for 1 to 6 months
• December 26, 2022

For Type 2 Diabetes "I completed 4 weeks on 2.5 mg with zero side effects, other than the intended appetite suppression and lost 10 pounds. HOWEVER, after my second week at 5mg, I'm not sure I can continue. I've had awful nausea, vomiting, sulfur burps, and diarrhea, to the point I had to go to the ER for IV fluids and potassium. Zofran, Phenergan, Tums, and Pepto have zero effect. I can barely function, but hey, I'm down a total of 17 lbs in 6 weeks, so at least I'll look skinny for my next trip to the ER."

• Ric...
• Taken for 1 to 2 years
• February 5, 2025

For Type 2 Diabetes "I currently have renal failure. I needed a kidney and pancreas. I was on the list for both. I did all my workups, even a triple bypass. My doctor put me on Mounjaro because of my heart surgery and diabetes. The Mounjaro worked so well it fixed my pancreas, and now I’m just on the list for a kidney. The side effects of using it were a little diarrhea and weight loss. I was 300-plus pounds, now I am under 160. Plus, I am no longer needing insulin for my diabetes. It’s practically gone."

• Kay...
• Taken for 1 to 6 months
• January 10, 2025

For Weight Loss (Obesity/Overweight) "I started taking Mounjaro 2.5 mg on September 6th, weighing in at 128 kilos. I'm now on my 7th shot of 10 mg (as I stayed on 10 mg for another month over Christmas) and I weigh 106 kilos in January. This is without changing my lifestyle of exercise or food. I eat smaller portions and don't think about food half as much as I used to. It's been great up until my 6th shot of 10 mg. I would experience mild side effects of nausea, vomiting, diarrhea, sulfur burps. These tended to be spread across the board as well though, never all at the same time, and it was manageable. However, my 6th dose I felt instantly! I was nauseous for 3 days straight, vomiting, diarrhea, sulfur burps, tired, the list is endless. I was so worn out by the nausea, I couldn't sleep, eat, or drink. I took myself to the walk-in center at the hospital where they referred me straight to A&E for having a resting heart rate of 128 bpm. I was put on an IV drip, bloods taken. I felt awful and still do! Going to go back to 7.5 mg."

• Pen...
• Taken for less than 1 month
• September 23, 2022

For Type 2 Diabetes "I started taking Mounjaro on 9/1. This resulted in the very worst month of my life. WEEK ONE - Super Nauseous, indigestion, stomach pain for 3-4 days of the first week. My appetite went from a 10 to a 2 (which was good). WEEK TWO - I had diarrhea for 3-4 days, along with sulfur belches, nausea, stomach pain. I ended up having to take sick days and go get an IV bag to recover from the dehydration. WEEK THREE - World-class nausea and vomiting. 3 days of vomiting so hard that I ruptured my esophagus. The entire month, if I was not having diarrhea, I was VERY constipated. I lost 9 lbs in one month, but I don't know if it was because I could barely eat due to the sickness. PASS!!"

• Anonymous
• Taken for 1 to 6 months
• March 29, 2023

For Weight Loss (Obesity/Overweight) "I'm on month three. My doctor thinks I might be too sensitive to it and may have to stop soon. Extreme nausea, occasional vomiting, and sulfur burps followed by diarrhea, weakness, and lethargy. The pros: in three months, I've gone from 262 lbs to 239 lbs."

• MTO...
• Taken for 6 months to 1 year
• May 14, 2023

For Weight Loss (Obesity/Overweight) "This medication has been a huge blessing in my life. Started at the lowest dose in August of 2022. Increased each month to the highest dose and have stayed there for 3 months now. It's May of 2023, and I have lost 80 pounds! I was pre-diabetic, depressed, and hopeless. I've had a bit of stomach upset, diarrhea, heartburn, gas... nothing terrible. But I feel so much better. My joints don't hurt hardly at all, I have more confidence to go places and talk to people and do stuff outside, and I even sleep better. I was looking into bariatric surgery before I found Mounjaro. I'm so glad I didn't have to do that."

• Anonymous
• Taken for 1 to 6 months
• January 19, 2023

For Type 2 Diabetes "I tried Ozempic for 9 weeks and thought I was going to die, so they switched me to Mounjaro. The 1st 2 weeks were okay, I just didn't have an appetite, but week 3 hit me just like Ozempic did. Total exhaustion. I've lost 5 lbs in a little over 3 days. I have side effects of sulfur burps, dehydration, constant nausea, falling asleep at all times, all-night vomiting, and diarrhea. I feel bruised from head to toe and have blurred vision. I'm telling people this for a warning. Read the reviews. People are constantly going to the ER because of these medications. I'm flustered because I found something that worked for my diabetes, but it is really bad for me. Since starting Ozempic up to now, I've lost almost 30 lbs... might sound great, but not when you can't function."

• Jim...
• Taken for 1 to 6 months
• September 24, 2022

For Type 2 Diabetes "Started at the 2.5 level and lost some weight (15 lbs.). Sugars are down as well. Greasy foods are not recommended. Went to the 5.0 level and everything dairy went bad... sours on the stomach badly and quickly. Ate too much one night and got very ill, vomiting and diarrhea all night along with serious gas from both ends! I don't like that I can't have my dairy, even tried Lactaid to no avail. Also, there seems to be a metallic taste in my mouth most of the time."

• kim...
• Taken for 1 to 6 months
• September 13, 2022

For Type 2 Diabetes "I started out on the 5mg and was deathly ill from it for about a week, with severe diarrhea and belching that was so awful it made me want to vomit. I lost 9 pounds, and my sugars are going down and staying where they are supposed to be. I called my doctor, and she switched me down to the 2.5mg, better just one day of illness. Started back on the 5mg, and I still feel horrible for 24 hours after day 2 of the shot. But sugars are awesome, and I'm hoping this too will pass."

• Rck...
• Taken for less than 1 month
• January 2, 2023

For Type 2 Diabetes "My doctor recommended Mounjaro. I objected because of previous experience with side effects from Byetta, Victoza, and Trulicity. He said the side effects were mild. I agreed to try 2.5, that was a horrible decision! My heart rate elevated, pulse and blood pressure increased, couldn’t eat, diarrhea, vomiting, loss of sense of balance. Went to the doctor 2 days later, and I was so dehydrated I required 2 1/2 bags of IV solution to help me drive home. I can’t remember ever being so sick. I will never take it again or recommend it to anyone!"

• kto...
• Taken for 1 to 6 months
• November 7, 2022

For Type 2 Diabetes "I started Mounjaro 7 weeks ago. The first shot made me so nauseous and have such bad abdominal pain that lasted for 12 hours. I almost went to the ER. I told my doctor about my experience, and she gave me Zofran and told me to continue dieting. Fast forward to this weekend - took my shot on Friday morning, then spent all day Saturday and Sunday projectile vomiting (it literally ended up about 7 feet from where I was standing), uncontrollable diarrhea, disgusting sulfur burps, horrible heartburn, and dizziness. Finally, I decided to go to the ER and got treated for dehydration. They told me to follow up with my primary doctor to talk about the best way to continue the medication. After this experience, I am NEVER taking this drug again. While I've lost 25 lbs in the past 7 weeks, I believe it's mostly because I've been afraid to eat anything. I will continue to eat healthy and cut carbs and sugars, but I won't be taking Mounjaro again."

• Cry...
• Taken for 1 to 6 months
• September 20, 2022

"My doctor prescribed Mounjaro after seeing my weight increase. First, I am a bariatric weight loss patient - 6 years out. I lost 80 lbs after my surgery and gained 30 back since. So yes, there is reason to be concerned. The month supply of 2.5 mg dose produced a 5 lb weight loss, and my appetite was suppressed somewhat. But more noticeable is the craving loss. They completely went away. I'm anxious to see how the 5 mg dose works. Some annoying side effects, but nothing drastic so far. Light nausea and diarrhea (subsides somewhat following the first few days after dosage). It took me a bit of time to get it together and start making healthy choices. I was in a very stressful work environment and chose to retire a little earlier than planned. Now, I work part-time from home now so I can take care of myself better. That's just me... I get overwhelmed and spiral. But even seeing this small amount of weight loss from the 2.5 dose has given me lots of hope and motivation!"

• Dut...
• Taken for 1 to 6 months
• March 8, 2025

For Type 2 Diabetes "My appetite and being a lifelong ‘foodie’ hit a final conflict point four years ago when I lost my ability to work off my weight easily. My knee pain and depression combined to make me asocial, deeply uncaring about my condition and convinced of no hope. I am pretty miserable. At 15 mg a week, food has moved from center stage to a stronger support character. Only one bout of intestinal irritation has marred my experience with diarrhea, vomiting, pain. But my insulin levels remain superb and my glucose monitor has become a friend, not an inevitable betrayer."

• Din...
• Taken for less than 1 month
• December 10, 2024

For Type 2 Diabetes "In the two doses, my blood sugar has been lower, my appetite has diminished, and I had no side effects. At the end of the second week (Saturday), I woke up during the night with stomach pain, diarrhea, and belching. After 6 hours, I finally vomited up undigested food that had been in my stomach for over 12 hours. It looked like I had just eaten. I avoided all food until Sunday morning, eating 1/2 of a plain English muffin. I had Lipton chicken soup, a piece of Bavarian pretzel, and a few french fries (picking from my wife’s meal). Monday, I finally felt hungry and had a Whopper Jr. (not a good choice I know), and Tuesday I woke up with food sitting in my stomach and one diarrhea BM. NOTE: I have not taken dose #3, nor do I plan to. This is slowing my digestion down too much. I have never had digestive issues, and I’m not going to start now."

• Ton...
• Taken for 6 months to 1 year
• February 26, 2023

For Type 2 Diabetes "I started on a 2.5 mg dose for 30 days and had nothing positive or negative. The doctor increased it to 12.5 mg, and my appetite went to zero, stomach pain, throw-up, diarrhea, general nausea, and ill feeling, but did lose 15 lbs in 3 weeks, and my blood labs were near perfect. I was ready to quit until I saw this. The second month, my appetite came back slightly, and I learned to eat less and cleaner so it wouldn’t make me throw up, lost another 15 lbs, and it excited me to get back in the gym daily. Since the drug slows your digestion, it slows the bowel too, which gave me insane constipation and made sure I eat enough fiber daily. At first, the side effects are hell, but stick with it as they only lasted a month, then your body adjusts and you learn how to eat and work with it. The end results are worth it. It's been 9 months, and I have lost 35 lbs, labs are excellent, and for the first time, I have seen glucose under 100 in 30 years."

• Lin...
• Taken for 1 to 6 months
• November 10, 2024

For Type 2 Diabetes "I’ve been taking 2.5 ml for 4 weeks and had few side effects apart from zero appetite, a little nausea, and a migraine (think the migraine was due to not eating). Now, week 5, increased to 5 ml and a different story: quite a lot of nausea, diarrhea, headache, and tiredness. Also again, total lack of appetite. Fortunately, these side effects more or less calmed down 2 or 3 days after taking the dose. I’m hoping it’s a temporary thing when you take a new dose - I can live with that."

• Mou...
• Taken for 1 to 6 months
• January 27, 2025

For Type 2 Diabetes "I have been on Mounjaro for 7 weeks. The first 4 weeks the dosage was 2.5, and the last 3 weeks it was 5. I love Mounjaro! It takes away my food obsessions and sugar cravings. It lets me focus on life rather than on food. I did get a few minor incidents of diarrhea and an occasional minor feeling of nausea, but they were nothing serious. Mounjaro has helped me lose 15 pounds in 7 weeks and brought my blood sugar from 220 to 120. I wish it were cheaper, but it has been worth it for me."

• MAW...
• Taken for 1 to 6 months
• November 11, 2022

For Type 2 Diabetes "I started out on the 2.5 for 2 months and lost 15 lbs, and my A1C dropped from 6.7 to 6.0. Mild side effect symptoms of abdominal pain and nausea. I started the 5 mg and had explosive diarrhea and uncontrollable vomiting, with abdominal and back pain. My blood pressure dropped to 88/55. I had to stop taking the Mounjaro. After 3 weeks, I am starting to feel normal again. Sorry it didn’t work for me. It did curb the appetite."

• WE...
• Taken for less than 1 month
• November 8, 2022

For Type 2 Diabetes "Went to the doctor and asked for something to help lose weight. He prescribed this medication. Day 1 and 2... nothing. Day 3 woke up with horrible heartburn and sour sulfur burps and facts and was constipated. By day 3 evening, I no longer had constipation but just the opposite... diarrhea! And not just any kind, it was like yellow water and very acidic. It hurt! Had horrible gas and belching all day Saturday, and Sunday couldn't hardly leave the bathroom to go buy Imodium. Imodium helped with that, but the gas is now trapped, and my stomach hurts badly, and I am full of gas with bad heartburn and belching. I saw a correlation between fatty foods and severe side effects of this product. But unless you're a vegan, you eat fat, and that's a major problem with this product. It is now Monday night, and I cannot seem to get my work done, I hurt so badly. I will never take this product again, and I cannot in good conscience recommend it with all the terrible side effects. Shame on Mounjaro!"

• Mat...
• Taken for 1 to 6 months
• March 4, 2025

For Type 2 Diabetes "I am just getting back on after having to quit for hip joint replacement surgery. I am up to 7 mg now. My daily glucose level is going down. I’ve had some weight loss. But the side effects are discouraging. Excessive gas, burping, bloating, diarrhea, and fluttering inside my chest. These symptoms last 2 or 3 days after injection. I am going to continue injections in the hope the side effects get better."

• Not...
• Taken for less than 1 month
• October 23, 2022

For Type 2 Diabetes "I’m struggling to get below 154 lbs, and being 5’, that’s a lot of weight to carry, which induces back pain. Lost 20 lbs on Ozempic from the beginning of the year till June, have managed to gain back 5 lbs, which isn’t awful but still not at my goal weight. I just left the ER from getting a bolus of saline due to dehydration. I’m battling hypoglycemia. I took my first shot on Tuesday. Wednesday felt decent, but malaise was setting in. Thursday, I didn’t even realize I had not eaten all day and all night at work. Friday night, I tried to eat half of a sandwich and was completely nauseous. Tonight at work, after eating half a sandwich and a few green beans, I had terrible diarrhea and became so dizzy and nauseated I was forced to leave work, having someone else take over my patients. Just a word of advice: if you’re a busy person, this med may not be for you. I had side effects of fever, chills, nausea, diarrhea, fatigue, and muscle pain, and I was negative for flu, COVID, and strep. The doctor said to go back to Ozempic :( but I’ve lost 6 lbs already!"

• Sev...
• Taken for 1 to 6 months
• March 25, 2025

For Type 2 Diabetes "Type 2 - I had been on Ozempic. It made me vomit/diarrhea, had Charley horses and hand tremors, and I was belching acid. After 3 months, my Endo switched me to Mounjaro, stating it was stronger, but many people tolerate it better. Week one, I was sick six days. All the same symptoms I had on Ozempic, only more severe. Heart rate 15 beats higher per minute. Week two, I was sick five days. Week three, within 12 hours, all the same symptoms began, and more. The vomiting was severe (mouth and nose). The belching was rank smelling/tasting. Diarrhea. My appetite was definitely curbed. My belly sounded like a flood of water flowing through my innermost pipes but felt numb. Eyes were so dry. My watch alerted me that at night my respiration rate was dipping to 7.5. (Did not even know my watch tracked that!) My heart rate dipped to 45. My blood sugar went to 43. Felt like I was not going to breathe or control peeing. And more! Day five, I ended up in the hospital in AFIB with a high heart rate. ICU."

• Kev...
• Taken for 1 to 6 months
• October 10, 2024

For Weight Loss (Obesity/Overweight) "It has worked, very positive results. No side effects after 11 weeks. I was on Saxenda and had many side effects, including episodes of gout, diarrhea, and indigestion (sulfur-tasting burps). I highly recommend it but caution folks to not rush increasing the dose (2.5 mg, then 5 mg, then 7.5 mg, etc. -- I took each dose for 4 weeks before increasing -- a friend skipped from 5 mg to 10 and became very ill). My only complaint is that it is very expensive for me because my insurance will not cover it for weight loss."

• Joj...
• Taken for 6 months to 1 year
• February 3, 2025

For Type 2 Diabetes "I started Mounjaro in March 2024 at 193 pounds and an A1C of 12.3. For almost 11 years as a type 1 diabetic. By July 2024, I was down to 153 pounds and an A1C of 7.75. I started off with the two, then went to the five, then to the seven, then to the 10. But after being on a 10, I started back developing an appetite, however, I exercised at least two hours per day faithfully in the gym. When I was on the number five, I had diarrhea a lot. When I made it to the 10, I just had a lot of belching, burping, saying that the 10 wasn’t doing much, I was still at like 150. I was bumped up to the number 12, and Lord have mercy on my soul. It almost took me out of here! I lost weight too fast. I got down to 116 pounds. I couldn’t. I didn’t have any desire to eat. I didn’t have any desire to drink. I would forget that I hadn’t been drinking anything. I would forget that I didn’t eat anything, and I’m still going to the gym every single day. It was until I dehydrated twice that I..."