Wegovy and Vomiting: What Users Say

• Slo...
• Taken for 1 to 6 months
• April 3, 2023

For Weight Loss (Obesity/Overweight) "Starting week 9 with the second injection of 1 mg. I have lost 24 pounds in 8 weeks. The side effects happen about 3 - 4 days a week. The first weekend on 0.25 mg was the worst! I really thought I needed my last rites! I have had headaches, nausea, vomiting, and bowel issues but not like the first-week episode. I try to eat light the day of the shot and take it at night because it makes me tired. You have to stay positive and just buy meds that will help with side effects because the side effects will probably always happen a couple of days a week. Try to drink 1/2 gallon of water a day and stay away from red meat, fried food, fast food, (most) dairy and sugar. If you don't, you will feel sick from eating that stuff. Also only eating one cup of food every couple of hours has made a huge difference in the nausea. Stock up on SF ice pops and SF Gatorade. I am so grateful that I got Wegovy with my insurance and when I want to quit, I just remember how many people would love the opportunity."

• Anonymous
• Taken for less than 1 month
• January 22, 2022

For Weight Loss (Obesity/Overweight) "Worst experience of my life. After the second 0.25 dose, I was up all night vomiting and diarrhea. The next day, I had chest pain, shaking, brain fog, stomach pain, more diarrhea, and had to go to the ER. After they gave me Benadryl and morphine, I started to feel better. Still have burping, gas, and acid reflux terribly. WILL NEVER TRY THIS AGAIN! It is not worth it to me! Wish it would hurry up and get out of my system."

• Sks...
• Taken for less than 1 month
• May 25, 2023

For Weight Loss (Obesity/Overweight) "I never leave reviews and rarely have side effects from medication. However, after one injection on the lowest dose, I am so beyond sick. Two days after my injection, I got a migraine followed by extreme vomiting for 4 days, chills, nausea, and a trip to the ER. This medication made me so unbelievably sick, it is like I've been poisoned. I have missed 4 days of work and am so weak. Living on Pedialyte and numerous nausea medications. Please be so careful. I was so hopeful and had no idea this would happen to me."

• RNi...
• Taken for 1 to 6 months
• May 4, 2022

For Weight Loss (Obesity/Overweight) "Wegovy does work, problem is... I feel like dirt all day long. I'm fatigued, nauseous, and even the smell of food makes me vomit. My heart races, and I'm quite dizzy. I lost 55 lbs. Do I look good? Yes. Do I feel good? No. I'm down to 153 lbs now. It's time to stop this medication."

• Jac...
• Taken for less than 1 month
• March 12, 2023

For Weight Loss (Obesity/Overweight) "Worst medication ever. On the lowest dose, I became deathly ill. I couldn't stop vomiting for a week. I could not walk because of extreme dizziness, and I could barely see from blurry vision. It also gave me the worst migraine of my life and suicidal thoughts and depression. I only lost weight because I could not eat at all and couldn't keep liquids down, so I was severely dehydrated. The side effects and long-term effects are so severe that the minor weight loss you would have from this medication is not worth it."

• Fin...
• Taken for 1 to 6 months
• July 5, 2022

For Weight Loss (Obesity/Overweight) "57-year-old on this for 3 1/2 weeks. I'd like to tell you how much I lost (was 4 pounds at 3 weeks), but I am so constipated for 4 days I cannot be sure what my real weight is (it could be 6 pounds now). Get a telemedicine provider to send you a vial of semaglutide (not the pre-loaded syringes) and use an insulin syringe to administer 1/2 the dose on one day with an ODT Zofran, then take the second half of the dose 24 hours later with another ODT Zofran. I administer in my outer thigh, like you would give insulin. The provider will tell you exactly how many 'units' to administer per week, just cut it in half, say Saturday and Sunday. Take a stool softener on Sunday, which I forgot to do this week! I have had zero gastrointestinal issues, no nausea, no vomiting. The Zofran may be causing some of the constipation, and I don't consider this a real issue, just a minor side effect with an easy fix. I am a Nurse Practitioner, so I have been watching everything for real side effects. I'll update."

• Lor...
• Taken for less than 1 month
• October 3, 2023

For Weight Loss (Obesity/Overweight) "I was prescribed Wegovy for weight loss purposes. I’m 5’11, 225 pounds, with a BMI of 31%, so I can be considered obese. I’ve been on it for one week and have lost 7 pounds. I’m starting with the lowest dosage (0.25). First of all, the injection was completely painless (for me). I also inject Humira bi-weekly, so maybe I’m just used to it, but I was shocked to feel absolutely nothing. I questioned if I was doing it right, it was so painless. Do not let some testimonials scare you! I did a lot of research while waiting for the drug to come back into stock. 90% of what I read were complaints about vomiting, diarrhea, some people getting so sick they had to go off of it. Some of these reviews were written after only a week or two of the drug usage. So far, my personal experience has been completely different than what I’ve read. That could change as I go up in dosage. As of right now, the only side effect I’m experiencing is a complete lack of appetite."

• Wag...
• Taken for less than 1 month
• April 5, 2023

For Weight Loss (Obesity/Overweight) "I took my first shot of 0.25 five days ago. I was extremely nervous about taking it due to all of the negative side effects that I read others have had. I decided to inject in my upper thigh late on a Friday afternoon so that if I did feel sick, I had the weekend to take it easy and deal with it. The injection was painless and very easy to administer myself. I honestly noticed no side effects after taking it, other than not thinking about food as much and wanting to eat a little less. I did push the boundaries on the third evening after taking it, and I did have bad nausea, I actually vomited and felt generally ill for about 16 hours (not bad enough to not work though). I pushed the boundaries by overeating air-fried chicken wings (no sauce) that were a bit more greasy/oily than normal. Those really set me off, and I realized that I: 1. can no longer eat any type of greasy food and 2. cannot eat too much. As long as I stick to my normal healthy, low-carb diet, I feel just fine (so far)."

• Tom...
• Taken for 6 months to 1 year
• April 13, 2023

For Weight Loss (Obesity/Overweight) "Started Wegovy in March 2022 with a goal of losing 50-75 pounds. I ended up losing a total of 85 pounds in about 11 months. I felt great upon taking the Wegovy. Only had mild headaches and mild stomach discomfort. I was not tired, I actually felt energized. However, by December, the nausea had reared its ugly head. I took Zofran, and it helped. I was able to stick it out with the nausea until February, at which time I stopped taking it. I could no longer live with the nausea. Since I stopped taking it, I have continued to suffer nausea, vomiting, and stomach pain. My doctor and I are still trying to find the source of this continuing issue. I love the weight loss, and I love Wegovy!"

• Ano...
• Taken for 6 months to 1 year
• April 20, 2025

For Weight Loss (Obesity/Overweight) "I started Wegovy in October at the lowest possible dosage and worked up to 1.7 by February. I had no side effects and very slowly lost weight, which I was fine with. I lost 35 pounds in six months. However, oddly enough, after five weeks at 1.7 with no side effects, I became quite ill. I started having the sulfur belches, followed by vomiting and severe diarrhea. I went to urgent care. They said it was a normal response and to take anti-diarrhea meds. I did. It got worse, to the point of diarrhea every 15-20 minutes. After six days of this, I went to the emergency room. They admitted me. I spent nine days in the hospital with severe dehydration, which caused my kidneys and pancreas to start shutting down. Docs felt I had a separate bacterial bug not caused by my shots. I was finally able to go home. My doctor had me start back at a safer .25 dose. I did, but immediately got sick again. I think I need to stop these meds, sadly, as they did originally help me, but I can’t go on this way."

• MM...
• Taken for 1 to 6 months
• December 22, 2022

For Weight Loss (Obesity/Overweight) "Wegovy has agonizing side effects. I had to quit after 2 months. Constant, uncontrollable vomiting, I vomited at work and while driving (which was horrific and dangerous). I essentially became bulimic and afraid to eat. I lost 20 pounds but put half of it back right away. Not worth the agony."

• MM...
• Taken for 1 to 6 months
• December 22, 2022

For Weight Loss (Obesity/Overweight) "Wegovy has agonizing side effects. I had to quit after 2 months. Constant, uncontrollable vomiting, I vomited at work and while driving (which was horrific and dangerous). I essentially became bulimic and afraid to eat. I lost 20 pounds but put half of it back right away. Not worth the agony."

• 188...
• Taken for 1 to 6 months
• May 17, 2023

For Weight Loss (Obesity/Overweight) "Started Wegovy 3 months ago using the gradual phase-up method. From 0.25 mg dose for 4 weeks to 0.50 mg dose for 4 weeks, then 1.0 mg dose for 4 weeks. During the initial phase, I experienced mild nausea and some stomach irritation. With each increase, the symptoms got worse until finally, at the full 1.0 mg dose, I was so sick I thought I had stomach flu for 2 weeks continuously. The belching was horrible. The nausea caused uncontrollable vomiting, and I had frequent diarrhea. After 3 months, I lost 12 pounds and felt horrible every day. I've now reduced the dose to 0.5 mg but still suffer from nausea and stomach upset. I might cut back again, but I'm thinking I will quit. The way I feel all the time is horrible! I'm thinking I lost weight because of all the vomiting. Not recommended."

• Abe...
• Taken for 1 to 6 months
• November 15, 2021

For Weight Loss (Obesity/Overweight) "Started out with .25 mg. I did that for four weeks and only felt slight nausea after the injection. Today, I bumped up to the .50 mg dose, and within five hours I was nauseous. I finally vomited, and I feel better, but have no appetite now. Nothing sounds good. I’m also sleepy. So far, the weight loss is only about five pounds. If I stay nauseated, it’ll probably increase drastically, but what a dumb way to live! I hope it’s temporary. I could be sick once a week and survive if I get decent weight loss. I am also fairly active, and I exercise 4-5 times a week. I don’t have a thyroid because of cancer nine years ago."

• Jan...
• Taken for less than 1 month
• January 9, 2023

For Weight Loss (Obesity/Overweight) "Took my first 0.25 mg Wegovy dose yesterday. I felt nauseous about an hour later, but within 2 hours, I started vomiting. For the next 16 hours, I dry heaved throughout the day and night. I couldn't even keep water down. It hasn’t been a full 24 hours yet since I took the shot and feel horrible, hoping that these side effects will stop soon. There is no way I’m taking another shot next week."

• Jan...
• Taken for less than 1 month
• January 9, 2023

For Weight Loss (Obesity/Overweight) "Took my first 0.25 mg Wegovy dose yesterday. I felt nauseous about an hour later, but within 2 hours, I started vomiting. For the next 16 hours, I dry heaved throughout the day and night. I couldn't even keep water down. It hasn’t been a full 24 hours yet since I took the shot and feel horrible, hoping that these side effects will stop soon. There is no way I’m taking another shot next week."

• Anonymous
• Taken for 1 to 6 months
• May 24, 2023

For Weight Loss (Obesity/Overweight) "Easy to administer, but during the first few weeks, had zero weight loss. Dose was increased. Woke in the middle of the night after the last dose with severe heartburn. Vomited every four hours for two days. Missed a day of work. Not able to keep anything down, including water. Put on anti-nausea medication. Have to sleep in a sitting position and take antacids and prescription meds to control heartburn enough to sleep. Cannot wait for the medication to get out of my system so I can function without vomiting or constant heartburn."

• Har...
• September 16, 2022

For Weight Loss (Obesity/Overweight) "Avoid this injection. I took my first dose a few weeks ago, and I have never been so sick. Constant vomiting after 4 hours, throwing up bile. Ended up in the hospital as I became dehydrated. A week later, still got on and off vomiting. The reflux is terrible and can't eat anything. It's better to be yourself than go through all this."

• Che...
• Taken for 1 to 2 years
• September 7, 2024

For Weight Loss (Obesity/Overweight) "I sat out on a journey to lose weight in January 2023. I am a heart patient, and I was weighing 220 lbs for the first time in my life. I started in the beginning, I had lots of nausea and vomiting as I went through the different doses. It wasn’t until I got to the highest dose that I really saw the change in my body weight. The weight just slid off. I lost a total of 100 lbs. I definitely changed my diet: high protein, grilled veggies, and fruit. I will say it changed my taste buds. Salty things were overwhelming to me while on Wegovy, and so was sugar. I can’t eat cheese at all without getting sick. But I feel better. My heart is doing well, and my lipids are finally in the normal range. This medication helped save my life, and I feel so blessed. Good luck on your new journey, and don’t be afraid to ask your doctor for nausea meds, it helps a lot."

• Ang...
• Taken for 1 to 6 months
• July 22, 2024

For Weight Loss (Obesity/Overweight) "I started on 0.25 Wegovy. The injections are painless and easy to administer. For the 4 weeks, I took this dose, I felt fine with little side effects. I lost 3 lbs. I then moved onto 0.5 dose. I took the dose on a Friday and woke in the middle of the night with terrible sudden reflux and vomiting. This happened for 3 nights. I took my next 0.5 dose the following Friday and the same happened, along with dizziness, constant nausea, and very low mood. I have decided not to take the last 2 injections I have left as I just feel so poorly."

• Bob...
• Taken for less than 1 month
• July 23, 2022

For Weight Loss (Obesity/Overweight) "Horrible experience after taking just the first dose. I’m going on my third week of being out of work. I have never been this sick. Violently vomiting one hour after my first and only dose. Heartburn, no energy, brain fog, couldn’t even speak coherently for the first 48 hours after taking. This stuff is like poison. Do not take it."

• Kar...
• Taken for 1 to 6 months
• February 2, 2022

For Weight Loss (Obesity/Overweight) "It works amazingly well, but the actual and physical cost was too much for me to continue. Been on it since August, and I've lost 40 pounds. That's really easy to do when you're starving due to constant nausea and vomiting. Though I'm terrified of gaining the weight back, as others described, I had to stop taking it as I was so sick every day and exhausted. I'm fighting it, but my appetite has already returned with a vengeance. That's not surprising, considering I've been malnourished for months."

• Ddd...
• Taken for 1 to 6 months
• February 11, 2022

For Weight Loss (Obesity/Overweight) "I have been on this medication since August 2021. So far, I have lost 36 lbs. I have been on the max dose of 2.4 for going on 2 months now. Side effects I have experienced have been sulfur burps/gas, nausea, vomiting, diarrhea, and sensitivity on my back and scalp (sunburn-type feeling). Although I haven’t had the most pleasant side effects, I would still recommend this medication. Now that my body is used to it and I am up to the max dose, I haven’t had any of the side effects lately, besides occasional nausea. I have noticed the most weight loss on the 1.7 and 2.4 doses. Just this week alone, I have lost 5 lbs. I hope to keep losing at this rate. I am only 40 lbs away from my goal weight now. So far, I have not really changed much with my diet or exercise. I cook my meals at home, drink water, and walk a few miles a week, and that is it. If you can stick it out and get up to the maintenance dose, it gets better!"

• For...
• Taken for 6 months to 1 year
• May 17, 2022

For Weight Loss (Obesity/Overweight) "I started Wegovy in December 2021 at 281 lbs, and as of May 2022, I am weighing in at 246 lbs (35 lbs lost). I am on the full maintenance dose at 2.4 mg. I didn't notice many symptoms early on; however, as I got to the 1.7 & 2.4 mg, my side effect symptoms greatly increased - including vomiting, nausea, diarrhea, and a nasty burnt popcorn taste in my mouth. This medication will definitely cause you to lose weight as it completely takes away your appetite, but the combination of side effects, mostly the vomiting, makes me question if I will stay on this medication much longer. For reference, I take my medication on Saturday evening and suffer the side effects until about Thursday morning. From Sun-Wed, I find myself in/out of the bathroom throwing up when I attempt to eat the most basic of foods. I used to have a large passion for food, but I can't imagine eating some of my favorite things while these side effects take over. I would recommend for those suffering to lose weight with caution."

• blh...
• Taken for less than 1 month
• May 31, 2024

For Weight Loss (Obesity/Overweight) "First dose 0.25mg, had slight stomach pain/discomfort. Later that same night, my appetite disappeared. Just seeing a fast-food commercial on TV made me feel nauseous. I thought if that's the worst of the side effects that affect me, then I'll be very happy with that. By the next day, stomach pain and nausea increased. By 4:00 am, BAM! Diarrhea, severe stomach pain, projectile vomiting, headache, chest pain, severe itching mainly on the palms of my hands and arms. I truly thought 'this must be what it feels like to be poisoned!' I was scared. It is now the next day and I feel fine. A little tired from lack of sleep from feeling so sick. I think I will do my second dose next week...but I'm quite nervous of a repeat of feeling like I was dying from the stomach pains and vomiting. Will I continue with this drug?...jury is still out! On the positive side, I've already lost 5 pounds; but of course, I can't & don't want to eat, too much nausea and vomiting."