Wegovy and Stomach Pain: What Users Say

• Anonymous
• Taken for less than 1 month
• January 22, 2022

For Weight Loss (Obesity/Overweight) "Worst experience of my life. After the second 0.25 dose, I was up all night vomiting and diarrhea. The next day, I had chest pain, shaking, brain fog, stomach pain, more diarrhea, and had to go to the ER. After they gave me Benadryl and morphine, I started to feel better. Still have burping, gas, and acid reflux terribly. WILL NEVER TRY THIS AGAIN! It is not worth it to me! Wish it would hurry up and get out of my system."

• Jed...
• Taken for 1 to 6 months
• December 15, 2021

For Weight Loss (Obesity/Overweight) "Halfway through the 1.7mg dose. Been on for about 4.5 months. Have lost a total of 35 pounds. My weight loss has slowed down since on the 1.7 dose. Still losing but not as quickly as in the beginning. Have no real interest in food anymore. Sometimes have to eat when not hungry due to low blood sugar (had this prior to Wegovy use). Been trying to lose weight for months. Wegovy is the only thing to work for my obesity due to medical issues. Have noticed off and on fatigue, dizziness, constipation, stomach pain, gas, belching, and hair loss. Can no longer eat fried, greasy food without feeling sick, which is good. Now I want healthy food instead."

• sou...
• Taken for 1 to 6 months
• March 23, 2023

For Weight Loss (Obesity/Overweight) "I am in my sixth week of Wegovy (4 weeks at 0.25 and now 2 at 0.5). I am a male in my early 50s, 5'9'' with a lot of weight to lose — about 120 pounds. In the first month, I experienced no side effects apart from reduced appetite and lost 10 pounds. I had just begun dieting when I started — nothing extreme, just eliminating the worst offenders: sugar, not eating after 6pm, and portion control. I have already lost 6 pounds this month. I have experienced some mild nausea this month on the 0.5 dose, nothing close to vomiting but definitely present, especially the two days after injection. Haven't had negative reactions to specific types of food like others have had until yesterday. Had some Korean BBQ and was burping garlic all night with some intestinal discomfort - so I guess that's a no go. I am considering holding at this dose before going up again. As long as the weight loss is happening at this rate, I am not keen to risk greater side effects."

• Shy...
• Taken for 1 to 6 months
• November 1, 2021

For Weight Loss (Obesity/Overweight) "Been on Wegovy for 7 weeks. Lost 14 pounds. 2nd week into 0.50 mg. It’s a little rough on my stomach. Taking prescription for nausea which happens the day of the injection. Feel tired and occasionally get severe abdominal pains. I can’t eat much and have to really watch the types of food. No greasy foods or spicy or heavy. The intestinal pains were very severe after eating wrong foods. I’m happy with the weight loss but the side effects are rough."

• Tom...
• Taken for 6 months to 1 year
• April 13, 2023

For Weight Loss (Obesity/Overweight) "Started Wegovy in March 2022 with a goal of losing 50-75 pounds. I ended up losing a total of 85 pounds in about 11 months. I felt great upon taking the Wegovy. Only had mild headaches and mild stomach discomfort. I was not tired, I actually felt energized. However, by December, the nausea had reared its ugly head. I took Zofran, and it helped. I was able to stick it out with the nausea until February, at which time I stopped taking it. I could no longer live with the nausea. Since I stopped taking it, I have continued to suffer nausea, vomiting, and stomach pain. My doctor and I are still trying to find the source of this continuing issue. I love the weight loss, and I love Wegovy!"

• GEF...
• Taken for 1 to 6 months
• January 9, 2022

For Weight Loss (Obesity/Overweight) "I’ve been using Wegovy for 12 weeks. I’m up to 0.50 and staying here. Tried 1.0 and it was too strong. Felt nauseous and experienced painful stomach cramps with 1.0. I have reached my goal weight. I lost 35 pounds and I’m very happy with the process and results. The only negative is, I’m on thyroid medication and noticed hot flashes and heart palpitations I didn’t experience before. I had my levels checked and they are way off! Consulting with my doctor. Not sure if I’ll continue Wegovy."

• A H...
• Taken for 1 to 6 months
• May 14, 2024

For Weight Loss (Obesity/Overweight) "First few weeks, appetite started to fall away. Lost 6 lb, then the sickness started - nausea, bloating, and stomach pain. Certain foods make this worse, and the nausea is daily now. On week 6 and down 9 lb, going to keep going unless this gets worse. It's like being pregnant again!"

• blh...
• Taken for less than 1 month
• May 31, 2024

For Weight Loss (Obesity/Overweight) "First dose 0.25mg, had slight stomach pain/discomfort. Later that same night, my appetite disappeared. Just seeing a fast-food commercial on TV made me feel nauseous. I thought if that's the worst of the side effects that affect me, then I'll be very happy with that. By the next day, stomach pain and nausea increased. By 4:00 am, BAM! Diarrhea, severe stomach pain, projectile vomiting, headache, chest pain, severe itching mainly on the palms of my hands and arms. I truly thought 'this must be what it feels like to be poisoned!' I was scared. It is now the next day and I feel fine. A little tired from lack of sleep from feeling so sick. I think I will do my second dose next week...but I'm quite nervous of a repeat of feeling like I was dying from the stomach pains and vomiting. Will I continue with this drug?...jury is still out! On the positive side, I've already lost 5 pounds; but of course, I can't & don't want to eat, too much nausea and vomiting."

• Anonymous
• Taken for 1 to 6 months
• May 3, 2023

For Weight Loss (Obesity/Overweight) "My experience so far is positive: 21 lbs down in 8 weeks. First, 4 weeks on .25 mg was great, no side effects. Weeks 5 and 6 were also good, slightly uncomfortable stomach but not bad, weeks 7 and 8, with 7 being not so bad. Then week 8, I had more stomach pain for a few days and didn’t have much of an appetite. Constipation is a real thing on this medication. Also, I am having a fast heart rate and seem to be a slight case of anxiety. Although I am experiencing some side effects, I am not giving up yet. I think for me, staying on a lower dose might be best. The .25 mg does work with fewer issues."

• big...
• Taken for 1 to 6 months
• May 27, 2024

For Weight Loss (Obesity/Overweight) "This is the first week at the 1mg dose, I lost 8 pounds last week. Before this, I was too scared to get on the scales, but I can feel I have lost significant weight. I have reduced appetite and cravings for sweet things that started almost immediately upon starting the drug. The only side effects I have had were, around week 3, constipation and trapped wind that caused waves of stomach pain for a few days. In the UK, you are supposed to be able to get this on the NHS if your BMI is over a certain level with associated health issues. However, no funding has been provided, so I am paying around £150-200 per month. This is offset by reduced food costs and alcohol costs that make it almost pay for itself."

• All...
• Taken for 1 to 6 months
• March 15, 2023

For Weight Loss (Obesity/Overweight) "I took 4 shots of .25 Wegovy. The first shot had no side effects and no problems. The second shot was a little different. Mild upset stomach starting about 24 hours afterward with some stomach pain. This subsided within the third day. My appetite was suppressed, felt fuller for longer. In the third shot, I had no appetite with stomach pain that lasted two days, and also felt as if I were going to pass out. I drank orange juice and ate saltine crackers with peanut butter, which helped. The last .25 shot of Wegovy… I had lost 12 pounds by this shot. But within a day, I was projectile vomiting, upset stomach, extreme pain in my abdomen, chills, and dizziness. I was taken to the emergency room. I was diagnosed with colitis that had gone to sepsis. The doctor explained a side effect from Wegovy may cause gastrointestinal problems. Wegovy attacked my colon and in turn, sepsis formed. I will not continue this shot. So many side effects go with it. It does curve your appetite, but I would be very cautious."

• Lis...
• Taken for 1 to 6 months
• January 29, 2022

For Weight Loss (Obesity/Overweight) "I started Wegovy 8 weeks ago. The coupon made it $25 a month. On the dose of 0.25, I had nausea and occasional diarrhea. On my 7th injection dose of 0.5, I got very sick: extreme nausea, diarrhea, and stomach pains. I skipped my next dose. I have been to the emergency room twice for fluids and anti-nausea medicine. The diarrhea is the worst of it-nonstop. I cannot keep anything down. I am down 23 pounds but feel miserable. I hope the medication wears off soon. I do not recommend the medication, it makes you feel so sick."

• Deb...
• Taken for less than 1 month
• December 12, 2024

For Weight Loss (Obesity/Overweight) "The first four days have been really rough. I’ve experienced nausea, vomiting, severe heartburn, and stomach pain. I really want this to work, so I’ll continue. The doctors have had to prescribe nausea and vomiting medicine. It helps. I’m taking Alka-Seltzer for the heartburn. I’m really hoping the side effects will stop."

• Mrs...
• Taken for 6 months to 1 year
• June 26, 2023

"I am on my 3rd week of the maintenance dose now and have hit a plateau. I've had no problems with us, though I will say that I've questioned if I've gotten the dose because the needle is so small you can't feel the injection, which, I guess, is actually a benefit. I've lost 21 lbs up until now. I've experienced horrid nausea and stomach pain. My appetite is definitely decreased - I only take a few bites of a meal and am completely full. I've many various health issues that keep me from traditional exercise, and I have just had knee surgery, so I am hoping to add an exercise routine in the coming weeks."

• Car...
• Taken for 1 to 6 months
• April 24, 2023

For Weight Loss (Obesity/Overweight) "I am on week 4 of Wegovy, the first 2 doses were 0.25 mg. The last 2 were 0.5 mg. I've had stomach pains and nausea to the point I'm in tears, it aches so much. My weight is going from 221 lbs to 215 lbs, I'm 5'9". I hardly eat for fear of worsening stomach issues. While my pharmacist says the side effects should go away by now, they haven't. I also have no energy, want to sleep, and have a hard time getting my blood sugar above 98, that's after a healthy meal with protein and a vegetable. Not sure this is worth it."

• Jen...
• Taken for 1 to 6 months
• April 7, 2023

For Weight Loss (Obesity/Overweight) "I have been on Wegovy for 8 weeks now (0.5 mg dose). I had occasional nausea, but this week I had diarrhea, vomiting, gas, nausea, and stomach pain. Thank goodness I was able to work from home, otherwise, I would have had to call out. I thought I had the stomach flu, but now I wonder if it's the medication. I am supposed to move up to the 1 mg in two days, but I am scared to. I took Ozempic for two months, and the only side effect I had was horrible heartburn, but it was very difficult to get, so I had to switch. I am contemplating not taking this anymore. I can handle some nausea, but to be so sick you can't function is a whole other thing. And I have not lost any weight."

• Aid...
• Taken for 6 months to 1 year
• March 7, 2025

For Weight Loss (Obesity/Overweight) "I’ve lost 30 lbs, and I’ve been on it for 7 months now. Currently on a maintenance dose. I experienced nausea, stomach pain, and constipation in the beginning, but no side effects now."

• Sic...
• Taken for less than 1 month
• June 11, 2022

For Weight Loss (Obesity/Overweight) "Doctor skipped to 1.7, and I’ve been sick going on 4 days now. Severe nausea and vomiting, stomach pain, and headache, dehydration."

• Dus...
• Taken for 1 to 6 months
• December 2, 2024

For Weight Loss (Obesity/Overweight) "Weight loss from the start, but severe constipation. Relieved by MiraLAX. Some stomach pain from time to time."

• Don...
• Taken for 1 to 6 months
• March 13, 2023

For Weight Loss (Obesity/Overweight) "I have had severe nausea and stomach pains, constipation, and back pain. Have had to stop taking it."

• Sco...
• Taken for less than 1 month
• December 28, 2024

For Cardiovascular Risk Reduction "So far, so good. I’ve been on it for 4 weeks now. I did have gas and stomach pain, nausea, and diarrhea, but that was in the beginning, and it’s lightened up a lot."

• bus...
• Taken for 1 to 6 months
• March 21, 2025

For Weight Loss (Obesity/Overweight) "I'm 58, 5'0", 161 lbs, postmenopausal. I've only lost 10 lbs in 5 months. Very disappointed I'm not losing more. Now having some eye pain and stomach pain."