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Seroquel User Reviews & Ratings (Page 5)

Seroquel has an average rating of 7.0 out of 10 from a total of 695 reviews on Drugs.com. 60% of reviewers reported a positive experience, while 20% reported a negative experience.

Reviews for Seroquel

Commonly mentioned side effects
  • Suc...
  • Taken for 6 months to 1 year
  • March 16, 2024

"Seroquel saved me too. I am so glad to read on here some of the same stories as mine. I have been through all of the meds. They only made me more anxious. I am on Seroquel plus an antidepressant and am happy. Glad you posted your stories! It made me feel better."

10 / 10
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  • bip...
  • July 15, 2016

For Bipolar Disorder "This medication was a lifesaver after being admitted in the hospital for being manic and very agitated. Was titrated from 50 mg to 250 mg a day, and it has cured my agitation 75%, my mood 50%, and my depression. Since most antidepressants make me manic, I would recommend it to anyone who has tried multiple medicines. I can finally sleep, feel relaxed, and not stay angry for hours."

9 / 10
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49 Report
  • BiP...
  • Taken for 1 to 2 years
  • September 5, 2017

For Bipolar Disorder "I try to avoid going on these forums because they always give me anxiety about the new medication I am trying out. I have let this forum make me think that side effects were happening to me that really weren't in the past. Seroquel is amazing. I have bipolar, and Seroquel was not out when I was first diagnosed. I started on it in May of 2016, and I have had to increase my dose by 100 mg since then, and it has changed my life. Seroquel has given me the ability to start to live my life more the way I want to live it. I wanted to post that here to not discourage someone who is starting out on it. My psychiatrist heard about this from one of the top bipolar doctors in the world speak at Harvard. This drug is wonderful and so helpful."

10 / 10
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44 Report

Frequently asked questions

  • Pat...
  • Taken for 6 months to 1 year
  • August 12, 2013

For Bipolar Disorder "I suffer from mainly depression and anxiety. I have had a few bouts of hypomania. This was recommended to me to help with anxiety and mood swings. Within an hour of taking this medicine, I was always somewhat buzzed and not in a good way. It felt like you had to lie down and sleep, or you would become extremely irritable. The sleep was great on it, however, you wake up in a fog for hours, usually until dinner time for me. It really flattens you out, so you don't feel much, just emotionless and tired. I took anywhere from 50 to 200 mg, and the result was the same. I am off now and trying safer meds. Seroquel wasn't for me, but I'm glad it helps millions, though!"

5 / 10
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  • Han...
  • Taken for 1 to 6 months
  • May 5, 2012

For Depression "I have been suffering from severe anxiety and depression after developing panic attacks. I have always suffered from generalized anxiety but have not had panic attacks for over 12 years. I haven't taken any medication during that time. I was driving home one evening, and out of nowhere, a severe panic attack hit me and left me immobilized on a bridge where I just froze. Fatigue, anxiousness, guilt, and dread. While I am receiving help from a counselor and my GP, I have been taking Zoloft 100mg in the morning and 50mg of Seroquel. Seroquel has helped me considerably. I take Seroquel at 6 PM, which usually helps me fall asleep by 9:30 PM and wake around 7 AM. This reduces the hangover effect. I am feeling better since taking Seroquel."

9 / 10
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  • Wil...
  • April 28, 2017

For Bipolar Disorder "So vivid in detail, from some, but give this medication time. This drug had me feeling some wacked out, like on a boat sensation. Just lightheaded and motion sickness. I was told 'six weeks,' so instead of stopping it, which I dearly wanted to, I didn't. And to this day, approximately four years, I thank myself I didn't. Yes, it's heavy-handed. But now I have nearly no racing thoughts, which drove me to suicidal tendencies. My mind never stopped, it was like a TV on in the background. Next, sleep, sleep, peaceful sleep. I did crave sugar, BUT NO WEIGHT GAIN. This drug is just broadly so good. This drug and a couple of others balanced me. The racing thoughts, Seroquel number one, but Ritalin was also something I am grateful for."

10 / 10
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  • shu...
  • June 1, 2020

For Bipolar Disorder "This drug Seroquel made me feel like a zombie. Sure, it would make me feel 'normal,' but it would completely knock me out. I was with some friends, and I was going to give them a ride home from my house and accidentally took my medication too early, and I literally passed out, and they had to get a ride from a friend. I was only at a 50 mg dose. This medication was just not for me. I take Latuda now, which made me really drowsy when I first started taking it, but I have since gotten over it."

2 / 10
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More FAQ

  • Jen...
  • Taken for 1 to 6 months
  • November 9, 2020

For Bipolar Disorder "Seroquel is terrible. I felt completely disassociated. I knew words were coming out of my mouth but sometimes had no clue what I was saying. I was only on it for a few months, but I called my Dr. in a panic when I’d realized the weight I’d gained. I lost 100 lbs in my 20s and have been able to keep it off give or take 10 lbs. I’m now 40 years old, and I instantly put on belly/waist weight, a place where I have NEVER gained before. I know my body well, and this was pretty extreme. I went up a pant size in 2 months. I told my Dr., and he said it makes you crave carbs, but I KNOW it’s more than that. What type of meds makes you gain weight in a specific area? After losing the 10-15 lbs, I am stuck with saggy skin after 3 months! It’s not worth it. It created a whole new set of permanent problems like saggy skin and my confidence with undressing around my husband. Horrible!"

1 / 10
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  • Sta...
  • Taken for 5 to 10 years
  • July 8, 2019

For Bipolar Disorder "I have been taking Seroquel for over 10 years. By far the best stabilizer for me. Previously, I had tried several meds. At first, my dosage was low, but kept climbing. Dosage went to 800 mg. I changed my psych doc, and she slowly walked me down to 400 mg. We even went down to 200 mg. But that was too low. I'm now at a happy medium. I do take lithium as well and Zoloft. I have been diagnosed bipolar for 25 years, so you can imagine the med changes in the past."

9 / 10
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  • Rom...
  • Taken for 1 to 2 years
  • November 5, 2012

For Bipolar Disorder "After later years of my adolescence and early adulthood, I was finally diagnosed (bipolar) and prescribed Seroquel along with lithium. Not only did I finally feel a sense of peace within myself, but I found that I no longer engaged in the reckless activity that I seemed to have no control over. This behavior, which caused so much grief and upset, nearly caused the breakdown between my family and nearly destroyed myself. It does not get rid of my depression completely, but they are not as bad, and I find I can cope, whereas in the past, I couldn't. I find that it's best to take it before bed as it makes me very drowsy, which I find a good thing because, in the past, I found it very difficult to sleep. Hope this helps."

10 / 10
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  • Bab...
  • October 13, 2009

For Bipolar Disorder "I am 53 years old and was put on this drug just over a year ago. I was diagnosed with severe bipolar disorder 13 years ago. I knew something was wrong with me when I was 17, but bipolar was not really known back then. This drug is by far the best thing I have ever taken. Don't worry about the weight gain, after a year, it will go away. It is a small price to pay for sanity. Everyone will get the munchies from this. I eat grapes at night, they do the trick. Have some in a bowl by your bedside, this will help keep the weight gain down. Stay away from ice cream and eat yogurt with preserves in it, or just fruit when you get the munchies 1 hour after taking it. I also take temazepam at night, 100mg."

9 / 10
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  • din...
  • Taken for 1 to 6 months
  • June 26, 2019

For Bipolar Disorder "I suddenly became manic and would have been hospitalized if it weren't for this drug. They started me at a baby dose, but with my emotions on fire, they quickly upped the dose to 100 mg. I'm 58 years old, and following this crisis, I was diagnosed with Bipolar II. I'm still agitated and angry during the day and having terrifying dreams due to PTSD. Everything that was buried inside me is now coming to the surface through therapy. They just raised the Seroquel to 300 mg. Hopefully, I'll be able to sleep. I've lost 5 lbs, when I gave up Trazodone and they put me on Abilify, my appetite was cut in half. I also take Lamotrigine 200 mg and Elavil 20 mg for migraines and fibromyalgia. To me, Seroquel is a wonder drug. Good luck!"

8 / 10
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  • Rac...
  • January 22, 2010

For Depression "I was prescribed one Seroquel 25 mg tablet at night for manic depression and insomnia. I couldn't be happier, my anxiety and depression were significantly reduced. My energy and mood dramatically improved, and I get great sleep every night. I wake up refreshed and ready to start my day. Also, it gives me the most vivid, wonderful dreams of all time. Taking this along with therapy from a psychologist is highly recommended for a successful outcome."

10 / 10
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70 Report
  • kel...
  • September 16, 2013

For Bipolar Disorder "It worked well for sleep, but I could not remember eating peanut butter and jelly sandwiches. I woke up with it all over my pillow and cheeks, weird. I felt hungover in the morning. Also, I was taking Geodon and Effexor. I don't take anything now. It's been 3 years. I'm doing good."

10 / 10
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  • Mac...
  • January 8, 2014

For Bipolar Disorder "I take Seroquel for bipolar. I had side effects when first taking it, such as couldn't wake in the morning and sluggishness. It took me a couple of months to get used to it. Now I take it at about 10:30 PM, asleep within 20 minutes, and up at about 8:30 AM, well rested. It has been great for my mania, which can last weeks at a time. I feel so normal again. I take 100 mg a night with 600 mg of Tegretol, you just have to give it time to do its thing, the side effects go away. I have no weight gain at all on Tegretol, it's the opposite, I'm losing weight."

9 / 10
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54 Report
  • sto...
  • November 20, 2019

For Schizoaffective Disorder "I have schizoaffective disorder and manic episodes, and Seroquel has helped me so much. I'm more calm, I eat better, sleep better, the only downside is when I do have episodes, they are full-blown, but it's better than the everyday I was experiencing."

8 / 10
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  • Blu...
  • Taken for 1 to 6 months
  • November 15, 2012

For Bipolar Disorder "Seroquel makes me feel like I'm on a level playing field again. I don't feel like my thinking's distorted, and I don't cry uncontrollably like I have all of my life. I have gained weight, but I'm fixing to start taking Topamax to counteract that. If the Topamax doesn't work, I will still continue to take Seroquel. I rather gain weight and be able to cope with life 100% better than I did before."

10 / 10
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  • Vik...
  • December 4, 2008

For Obsessive Compulsive Disorder "Seroquel has made a day-and-night difference in my life. I have huge anxiety issues and OCD. I've been taking 200 mg/night for a few years now. It's not for everybody with OCD, but it has been a lifesaver for me."

10 / 10
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  • Tan...
  • Taken for 2 to 5 years
  • December 8, 2024

For Schizoaffective Disorder "I am on 50 mg of Seroquel for sleep help because of anxiety, psychosis. I find it works like magic for sleep, calming me down, changing my perspective, turning off my head, inducing deep sleep with dreams, not nightmares. At the highest, I was prescribed for psychosis and schizophrenia, 600 mg. This caused my heart to race and feel like my heart would jump-start and be on a runaway train without stopping, which induced panic attacks so bad I had to call for emergency. My heart racing is one of the rarer side effects, I think. Also, at such a high dose, it really blocks the dopamine D2 receptor because it's trying to prevent schizophrenia, but it can dampen feelings, emotions, and interest levels in daily activities, I find. So I spoke to my psychiatrist, and she just prescribes me 50 mg for sleep help and another med for psychosis and schizophrenia problems."

10 / 10
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  • Blu...
  • Taken for less than 1 month
  • February 17, 2023

For Bipolar Disorder "This happened a really long time ago, in September 2008, when I was 14. I was recently diagnosed with bipolar and was always angry and crying, so I got prescribed this, but I only took it a few days because I fell down the stairs! Anyway, I had this intense, restless, cold feeling in both my legs, couldn’t stop moving, I couldn’t keep my eyes open, I gained 45 lbs, and I had no personality. My psychiatrist took me off when she found out what happened to me."

1 / 10
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  • Ano...
  • Taken for 1 to 6 months
  • April 11, 2016

For Schizoaffective Disorder "This drug worked perfectly. It controlled all my symptoms, paranoia, visual and auditory hallucinations, tactile hallucinations, and anxiety. Absolutely no weight gain. I lost 30 pounds on this medication and could not be happier that I tried the drug. It also works excellently for people with eating disorders, controlling their cravings and regulating their eating patterns. There were no sexual side effects. I never relapsed when I went off the medication with the help of my psychiatrist. Thank you, makers of Seroquel!"

10 / 10
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  • o_o...
  • Taken for 1 to 6 months
  • May 7, 2024

For Bipolar Disorder "I wanted to share my experience with this med because it has given me hope that recovery is possible. Before Seroquel, I was in and out of inpatient every 6 months for over 3 years, crippling SH problems, ED issues, MDD, severe verbal anger outbursts, and had max dosed a few different antidepressants and antipsychotics that never really did anything for me mentally (except causing weight gain, which contributed to my ED heavily). At my last inpatient stay, I was prescribed 200 mg Seroquel ER along with Prozac 40 mg after maxing out my Abilify (30 mg) and my Lexapro (20 mg) during the same stay. And within the following weeks (accompanied by group and individual therapy), I had made a visible change. Now, 5 months later, it feels like I have a lot of myself again, and I’m not cured, if that’s ever possible, but I don’t hate being alive. I don’t wake up wishing I hadn’t. It has only been a short amount of time, but it’s been helpful."

10 / 10
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  • Jax...
  • Taken for 1 to 6 months
  • February 1, 2016

For Bipolar Disorder "I was on this med in 2010 for a year. The dose went from 25 mg up to 400 mg. The first few weeks were very difficult. It knocked me out cold and I had such a blocked nose I could hardly breathe. I toughed it out and my depression lifted. I stopped taking it because of a really bad blocked nose. I have just had a major depressive episode (2015) with insomnia. I was prescribed 100 mg. It worked within 24 hours. I was able to sleep for 9 hours and feel refreshed and energized. The depression and anxiety have improved dramatically. This time I'll stay on Seroquel."

10 / 10
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  • Nui...
  • Taken for 5 to 10 years
  • March 21, 2017

For Bipolar Disorder "Very drowsy for the first week of taking it, but once your body gets used to it, it is a great mood stabilizer. I've been on it 6 years, and it calms the edginess and irritability with bipolar. Also makes you sleep like a rock. My weight only changed when lithium was added to my meds. No significant weight gain for me. If I go a few days without it, I notice I'm on edge constantly."

8 / 10
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  • Anonymous
  • February 12, 2010

For Post Traumatic Stress Disorder "The side effects that most complain about are what I love most about this medication. I am a 5'9" male in the Army that had lost weight all the way down to 128 lbs and was sleeping 3-4 hours a night on average. I have been on Seroquel for 4 months. I weigh 165 lbs now and sleep 8-9 hours a night."

10 / 10
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